Results 71 to 80 of about 12,416 (242)

First-in-Human PET Imaging of [18F]SDM-4MP3: A Cautionary Tale

Molecular Imaging, 2023
[18F]SynVesT-1 is a PET radiopharmaceutical that binds to the synaptic vesicle protein 2A (SV2A) and serves as a biomarker of synaptic density with widespread clinical research applications in psychiatry and neurodegeneration.
Kimberly L. Desmond, Anton Lindberg, Armando Garcia, Junchao Tong, Michael B. Harkness, Elena Dobrota, Kelly Smart, Carme Uribe, Jeffrey H. Meyer, Sylvain Houle, Antonio P. Strafella, Songye Li, Yiyun Huang, Neil Vasdev   +13 more
doaj   +1 more source

Phosphorus‐Structured Gel Electrolytes Enable Dual Protection for Thermal Runaway‐Resistant Lithium Metal Batteries

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The PD‐VI GPE synthesized via in situ γ‐ray polymerization facilitates formation of a dense F/P‐rich SEI layer, enabling stable Li deposition while suppressing interfacial side reactions. The phosphorus‐containing framework enhances separator thermal stability and effectively mitigates O2 release from cathodes, demonstrating improved safety under the ...
Zeyu Zhang, Fan Jiang, Xibang Chen, Mingshu Xie, Sontong Zhang, Pengchen Zhao, Xiayu Zhu, Jintao Li, Jing Peng, Weibo Hua, Wenqi Huang, Jiuqiang Li, Xue Yang, Bin Liao, Le Yu, Maolin Zhai, Jingyi Qiu   +16 more
wiley   +1 more source

Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain

Pharmaceuticals, 2022
The degree of acetylation of lysine residues on histones influences the accessibility of DNA and, furthermore, the gene expression. Histone deacetylases (HDACs) are overexpressed in various tumour diseases, resulting in the interest in HDAC inhibitors ...
Oliver Clauß, Linda Schäker-Hübner, Barbara Wenzel, Magali Toussaint, Winnie Deuther-Conrad, Daniel Gündel, Rodrigo Teodoro, Sladjana Dukić-Stefanović, Friedrich-Alexander Ludwig, Klaus Kopka, Peter Brust, Finn K. Hansen, Matthias Scheunemann   +12 more
doaj   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Recent Developments in Carbon-11 Chemistry and Applications for First-In-Human PET Studies

Molecules, 2023
Positron emission tomography (PET) is a molecular imaging technique that makes use of radiolabelled molecules for in vivo evaluation. Carbon-11 is a frequently used radionuclide for the labelling of small molecule PET tracers and can be incorporated into
Anna Pees, Melissa Chassé, Anton Lindberg, Neil Vasdev   +3 more
doaj   +1 more source

The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan, Saumya Nigam, Isabella Kasabasic, Medha Manepalli, Ping Wang, Jinda Fan   +5 more
wiley   +1 more source

THE RADIOCHEMISTRY OF IRIDIUM [PDF]

, 1961
The general and analytical chemistry of Ir are reviewed and applications to the radiochemistry of Ir are discussed. Topics covered include dissolution of samples containing Ir, counting techniques for radioactive Ir isotopes, radiochemical procedures for Ir radionuclides, and safety practices. A list is included of the radioactive nuclides of Ir.
openaire   +3 more sources

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

Medicinal Research Reviews, EarlyView.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller, Nadia Bom Pedersen, Vladimir Shalgunov, Andreas Ingemann Jensen, Umberto Maria Battisti, Matthias Manfred Herth   +5 more
wiley   +1 more source

On the adsorption and reactivity of element 114, flerovium

Frontiers in Chemistry, 2022
Flerovium (Fl, element 114) is the heaviest element chemically studied so far. To date, its interaction with gold was investigated in two gas-solid chromatography experiments, which reported two different types of interaction, however, each based on the ...
A. Yakushev, A. Yakushev, L. Lens, L. Lens, Ch. E. Düllmann, Ch. E. Düllmann, Ch. E. Düllmann, J. Khuyagbaatar, J. Khuyagbaatar, E. Jäger, J. Krier, J. Runke, J. Runke, H. M. Albers, M. Asai, M. Block, M. Block, M. Block, J. Despotopulos, A. Di Nitto, A. Di Nitto, K. Eberhardt, U. Forsberg, P. Golubev, M. Götz, M. Götz, M. Götz, S. Götz, S. Götz, S. Götz, H. Haba, L. Harkness-Brennan, R.-D. Herzberg, F. P. Heßberger, F. P. Heßberger, D. Hinde, A. Hübner, D. Judson, B. Kindler, Y. Komori, J. Konki, J.V. Kratz, N. Kurz, M. Laatiaoui, M. Laatiaoui, M. Laatiaoui, S. Lahiri, B. Lommel, M. Maiti, A. K. Mistry, A. K. Mistry, Ch. Mokry, Ch. Mokry, K. J. Moody, Y. Nagame, J. P. Omtvedt, P. Papadakis, V. Pershina, D. Rudolph, L.G. Samiento, T.K. Sato, M. Schädel, P. Scharrer, P. Scharrer, P. Scharrer, B. Schausten, D. A. Shaughnessy, J. Steiner, P. Thörle-Pospiech, P. Thörle-Pospiech, A. Toyoshima, N. Trautmann, K. Tsukada, J. Uusitalo, K.-O. Voss, A. Ward, M. Wegrzecki, N. Wiehl, N. Wiehl, E. Williams, V. Yakusheva, V. Yakusheva   +81 more
doaj   +1 more source

Unleashing the Potential of Defect Engineered Persistent Pr3+‐Activated Phosphors for Multi‐Dimensional Anti‐Counterfeiting and X‐Ray Imaging Applications

Small, EarlyView.
Enhanced multicolor persistent luminescence with optimized trap depths (≈0.73 eV) in Ca3Ga2Ge3O12:Pr3+ phosphors enable advanced anti‐counterfeiting, optical storage, and high‐resolution X‐ray imaging (4 lp mm−1), surpassing commercial screens.
Annu Balhara, Santosh K. Gupta, Partha Sarathi Ghosh, Malini Abraham, Mohit Tyagi, Ashok Kumar Yadav, Subrata Das, Kathi Sudarshan, P. S. Sarkar   +8 more
wiley   +1 more source