Results 1 to 10 of about 2,844 (146)
Hybrid (2D/3D) Dosimetry of Radiolabeled Gold Nanoparticles for Sentinel Lymph Node Detection in Patients with Breast Cancer. [PDF]
Contrast Media Mol Imaging, 2020 Previously, we reported the preparation and preclinical studies of 99mTc‐labeled gold nanoparticles‐mannose (99mTc‐AuNP‐mannose) with potential for sentinel lymph node (SLN) detection by using nuclear medicine procedures. This study aimed to evaluate the biokinetics and hybrid (2D/3D) dosimetry of 99mTc‐AuNP‐mannose in five patients with breast cancer ...
Ramírez-Nava G +7 more
europepmc +2 more sources
99mTc-CXCR4-L for Imaging of the Chemokine-4 Receptor Associated with Brain Tumor Invasiveness: Biokinetics, Radiation Dosimetry, and Proof of Concept in Humans. [PDF]
Contrast Media Mol Imaging, 2020 Overexpression of the chemokine‐4 receptor (CXCR4) in brain tumors is associated with high cancer cell invasiveness. Recently, we reported the preclinical evaluation of 99mTc‐CXCR4‐L (cyclo‐D‐Tyr‐D‐[NMe]Orn[EDDA‐99mTc‐6‐hydrazinylnicotinyl]‐Arg‐NaI‐Gly) as a SPECT radioligand capable of specifically detecting the CXCR4 protein.
Vallejo-Armenta P +10 more
europepmc +2 more sources
Development of 177Lu-scFvD2B as a Potential Immunotheranostic Agent for Tumors Overexpressing the Prostate Specific Membrane Antigen [PDF]
Scientific Reports, 2020 The clinical translation of theranostic 177Lu-radiopharmaceuticals based on inhibitors of the prostate-specific membrane antigen (PSMA) has demonstrated positive clinical responses in patients with advanced prostate cancer (PCa).
Debora Carpanese +10 more
doaj +2 more sources
177Lu-DOTA-HYNIC-Lys(Nal)-Urea-Glu: Biokinetics, Dosimetry, and Evaluation in Patients with Advanced Prostate Cancer. [PDF]
Contrast Media Mol Imaging, 2018 SPECT/CT images in patients have demonstrated the ability of [99mTc]Tc‐EDDA/HYNIC‐Lys(Nal)‐Urea‐Glu ([99mTc]Tc‐iPSMA) to detect tumors and metastases of prostate cancer. Considering that theranostics combines the potential of therapeutic and diagnostic radionuclides in the same molecular probe, the aim of this research was to estimate the biokinetics ...
Santos-Cuevas C +9 more
europepmc +2 more sources
Brazilian Journal of Radiation Sciences, 2020 O objetivo deste trabalho foi realizar uma revisão narrativa do cenário mundial dos radiofármacos para diagnóstico e estadiamento de câncer de próstata (CaP).
Heber Simões Videira +9 more
doaj +1 more source
Brazilian Journal of Radiation Sciences, 2019 Fludeoxyglucose F 18 ([18F]FDG) is the most used radiopharmaceutical for positron emission tomography, especially on oncology. Organic solvents such as ether, ethanol and acetonitrile might be used in the synthesis of [18F]FDG; however, they might not be
Flávia Mesquita Costa +3 more
doaj +1 more source
Avaliação do Controle de Qualidade de Radiofármacos em Serviço de Medicina Nuclear
Brazilian Journal of Radiation Sciences, 2015 Os radiofármacos são um tipo de preparação farmacêutica associada à radionuclídeos com finalidade diagnóstica e terapêutica. Serviços de Medicina Nuclear (SMN) devem realizar controle de qualidade dos radiofármacos conforme recomendações dos fabricantes ...
Tavares Lopes Almeida +2 more
doaj +1 more source
Um método proativo para gerenciamento da segurança em instalações nucleares [PDF]
, 2015 Em razão da abordagem moderna para tratar a segurança em instalações nucleares que destaca que estas organizações devem ser capazes de avaliar e gerenciar de forma proativa suas atividades torna-se cada vez mais importante a necessidade de instrumentos ...
CARVALHO, Paulo Victor Rodrigues de +2 more
core +1 more source
Radiopharmaceuticals drug interactions: a critical review
Anais da Academia Brasileira de Ciências, 2008 Radiopharmaceuticals play a critical role in modern medicine primarily for diagnostic purposes, but also for monitoring disease progression and response to treatment.
Ralph Santos-Oliveira +2 more
doaj +1 more source
Brazilian Journal of Pharmaceutical Sciences, 2014 Radiopharmaceuticals are compounds that have a radionuclide and may be gamma-radiation emitter (γ) or positrons emitter (β+), linked to a molecule with specific diagnostic and therapeutic purposes.
Maryelle Moreira Lima Gamboa +4 more
doaj +1 more source