Results 91 to 100 of about 9,985 (291)

YAP1‐Driven Pathogenic Fibro‐Adipogenic Progenitors Secrete IL‐6 and FGF21 to Mediate Muscle‐Bone Crosstalk and Promote Bone Loss

Advanced Science, EarlyView.
Fibro‐adipogenic progenitors (FAPs) in atrophic muscle undergo YAP1‐driven pathogenic activation, secreting IL‐6 and FGF21 as bone‐catabolic myokines that mediate muscle‐bone crosstalk and promote bone loss. Genetic or pharmacological targeting of this YAP1‐FAP‐myokine axis rescues skeletal deterioration, identifying FAP‐derived myokines as therapeutic
Xiaoyu Cai, Tao Xu, Rui Ma, Weikun Meng, Shutao Gao, Yakefu Abulizi, Alafate Kahaer, Chuanhui Xun, Maierdan Maimaiti, Rui Cao, Weidong Liang, Polati Maimaiti, Qiang Deng, Jun Sheng, Ting Wang, Mingchong Liu, Weibin Sheng   +16 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

Advanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li, Zhongguo Ren, Yiliang Lin, Xianfeng Xia, Tianlong Li, Kai Fung Chan, Philip Wai Yan Chiu, Wei Peng Yong, Mengmeng Sun   +8 more
wiley   +1 more source

Evaluation of radiographers’ mammography screen‐reading accuracy in Australia

Journal of Medical Radiation Sciences, 2015
Introduction This study aimed to evaluate the accuracy of radiographers’ screen‐reading mammograms. Currently, radiologist workforce shortages may be compromising the BreastScreen Australia screening program goal to detect early breast cancer.
Josephine C. Debono, Ann E. Poulos, Nehmat Houssami, Robin M. Turner, John Boyages   +4 more
doaj   +1 more source

Agreement in neonatal x-ray interpretation: a comparison between consultant paediatric radiologists and a reporting radiographer

, 2014
X-rays are frequently used by clinicians to aid in patient diagnosis and management; infants which require specialised neonatal care are no exception.
Aladangady, N., Iliadis, K., Prakash, R., Piper, K., Woznitza, N., Santos, R.   +5 more
core  

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Matrix Stiffness Enhances Odontogenic Differentiation of DPSCs through Membrane Curvature Protein Baiap2‐Modulated Exosome Release

Advanced Science, EarlyView.
Matrix stiffness softening is identified as a previously underappreciated feature in deep caries. Higher stiffness drives exosome release in dental pulp stem cells through a coordinated mechanism involving PI3K–AKT‐regulated Baiap2 and kinesin‐1, thereby promoting odontogenic differentiation.
Bilun Jin, Shaojie Dong, Yue Jia, Zhao Xu, Peiqi Liu, Zhaojing Ding, Yuxin Liao, Rui Zou, Jinsong Hu, Bo Cheng, Lin Niu   +10 more
wiley   +1 more source

In Situ Programmable Modulation of Hydrogel Stiffness for Stage‐Adaptive Bone Regeneration

Advanced Science, EarlyView.
Near‐infrared (NIR) irradiation triggers Ca2+ release from thermoresponsive nanocarriers, enabling in situ stiffening of an adaptive hydrogel from a soft to a stiff state, thereby sequentially supporting mesenchymal stromal cell stemness and osteogenic differentiation for stage‐adaptive bone regeneration.
Yuxin Yang, Fan Yang, Lu Wang, Zongtai Li, Weichang Li, Xinchun Zhang   +5 more
wiley   +1 more source

Veterinary nurse to medical diagnostic radiographer

, 2017
Nicholas Taylor is senior diagnostic radiographer at the Great Western Hospital, Swindon, having initially qualified as a veterinary nurse. It was a college lecture that initially sparked his interest in radiography – little did he know where it would ...
Nicholas Taylor
core   +1 more source

Further Evidences for the Sulfur Spillover on Carbon: Thermodynamic Aspects and Effects on Li‐S Solid‐State Batteries

Advanced Science, EarlyView.
ABSTRACT This study investigates sulfur spillover, the spontaneous and rapid spread of sulfur over carbon surfaces at ambient temperature. The process is studied by small‐angle X‐ray scattering (SAXS), X‐ray radiography, and microcalorimetry from which a number of physicochemical properties are derived.
Francesco Piccolo, Anka Berger, Sebastian Risse, Román Healy Corominas, Wilhelm Erth, Florian Fuchs, Jesus Andrade, Jörg Schuster, Marc Armbrüster, Philipp Adelhelm   +9 more
wiley   +1 more source

Investigating Factors Influencing Fatigue and Medical Imaging Technologist Performance on Night Shift: An Initiative to Improve Healthcare Delivery

Journal of Medical Radiation Sciences
Introduction It is widely recognised that night shifts can cause fatigue, negatively impact cognitive performance and increase the risk of accidents.
Trevor Gillbard, Dane Thompson, Nicole Emma Andrews   +2 more
doaj   +1 more source