Results 131 to 140 of about 18,757 (301)

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

FracFusionNet: A Multi-Level Feature Fusion Convolutional Network for Bone Fracture Detection in Radiographic Images

Diagnostics
Background/Objectives: Bones are essential components of the human body, providing structural support, enabling mobility, storing minerals, and protecting internal organs. Bone fractures (BFs) are common injuries that result from excessive physical force
Sameh Abd El-Ghany, Mahmood A. Mahmood, A. A. Abd El-Aziz   +2 more
doaj   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Nucleoside‐Based Hydrogel Platform Synergizes with Photothermal Effects for Enhanced Biofilm Eradication Against Periodontitis

Advanced Science, EarlyView.
A synergistic antibiofilm hydrogel platform (ZBAg@FNP) is developed by encapsulating an organic small‐molecule photothermal agent (FNP) within a silver ion‐mediated supramolecular hydrogel (ZBAg), enabling photothermal disruption of biofilm integrity and controlled Ag⁺ ion release upon irradiation.
Yinghui Wen, Yunfei Li, Tiannan Liu, Chongkui Sun, Hang Zhao, Yao Yuan, Shiping Yang, Tingxing Zhao, Jiang Liu   +8 more
wiley   +1 more source

Radiographic evaluation of healing of critical size calvarial defect treated with silica-collagen-hydroxyapatite biocomposite graft and homologous platelet-rich plasma in rat model

Journal of Veterinary and Animal Sciences
Seventy two adult male Wistar rats were selected and randomly divided into three groups with 24 rats. Calvarium of each rat was subjected to creation of 4.0 mm critical sized defect under general anaesthesia.
Deny Jennes, Laiju M. Philip, Syam K. Venugopal, S. Anoop, S. S. Devi, Leena Chandrasekhar, Francis Boniface Fernandez   +6 more
doaj   +1 more source

On The Application Of Log Compression and Enhanced Denoising In Contrast Enhancement Of Digital Radiography Images [PDF]

, 2023
M S Asif, Mahesh Raveendranatha Panicker
openalex   +1 more source

Beyond Imperfect Match: Silicon/Graphite Hybrid Anodes for High‐Energy–Density Lithium‐Ion Batteries

Advanced Energy Materials, EarlyView.
Silicon/graphite (Si/Gr) hybrid anodes are limited by Si's large volume change and mismatch with Gr. This review offers mechanistic insights into imperfectly matched Si/Gr hybrid anodes, elucidating heterogeneous lithiation behavior and interfacial failure pathways, and thereby informing the design of durable, high‐energy–density lithium‐ion batteries.
Jing Li, Karol Viviana Mejía‐Centeno, Malik Dilshad Khan, Guifang Zeng, Lijie Ci, Andreu Cabot, Qing Sun   +6 more
wiley   +1 more source

The combination of an inflammatory peripheral blood gene expression and imaging biomarkers enhance prediction of radiographic progression in knee osteoarthritis [PDF]

, 2020
Mukundan Attur, Svetlana Krasnokutsky, Hua Zhou, Jonathan Samuels, Gregory Chang, Jenny T. Bencardino, Perry Rosenthal, Leon Rybak, Janet L. Huebner, Virginia B. Kraus, Steven B. Abramson   +10 more
openalex   +3 more sources

Novel metaheuristic optimized latent diffusion framework for automated oral disease detection in public health screening

Scientific Reports
Automated oral disease detection systems face significant challenges from degraded radiographic imaging quality and limited pathological training data, particularly for rare conditions in public health screening environments. We introduce DentoSMART-LDM,
Marwa Sabry, Mostafa Elbaz, Waleed Obaid Alzabni   +2 more
doaj   +1 more source

Nondestructive evaluation of ceramic and metal matrix composites for NASA's HITEMP and enabling propulsion materials programs [PDF]

In a preliminary study, ultrasonic, x-ray opaque, and fluorescent dye penetrants techniques were used to evaluate and characterize ceramic and metal matrix composites. Techniques are highlighted for identifying porosity, fiber alignment, fiber uniformity,
Generazio, Edward R.
core   +1 more source