Results 41 to 50 of about 5,062,336 (201)

Current concepts of 131I therapy in oncology: Indications, methods and follow up [PDF]

Archive of Oncology, 2006
Radioiodine in various forms (as sodium iodide and as the iodinated compounds MIBG, LIPIODOL, et al.) has been used as a therapeutic agent in oncology. Differentiated thyroid carcinoma (DTC) has been successfully treated by 131I therapy.
Mihailović Jasna
doaj   +1 more source

In Silico Screening and Validation of PDGFRA Inhibitors Enhancing Radioiodine Sensitivity in Thyroid Cancer

Frontiers in Pharmacology, 2022
Aberrant activation of platelet-derived growth factor receptor α (PDGFRA) has been implicated in tumorigenesis and radioiodine resistance of thyroid cancer, indicating its therapeutic potential.
Xuefei Yu, Xuhang Zhu, Lizhuo Zhang, Jiang-Jiang Qin, Chunlai Feng, Qinglin Li   +5 more
doaj   +1 more source

Prognostic factor analysis in 325 patients with Graves’ disease treated with radioiodine therapy

Nuclear medicine communications, 2017
Introduction 131I therapy is a choice for Graves’ hyperthyroidism. Several factors that affect the success of 131I treatment in Graves’ disease (GD) patients have been put forward.
Danrong Yang, Jianjun Xue, Wenxia Ma, Furong Liu, Yameng Fan, Jie Rong, Aimin Yang, Yan Yu   +7 more
semanticscholar   +1 more source

Managing the adverse events associated with lenvatinib therapy in radioiodine-refractory differentiated thyroid cancer.

Seminars in Oncology, 2019
Lenvatinib is a multikinase inhibitor of vascular endothelial growth factor (VEGF) receptors 1-3, fibroblast growth factor receptors 1-4, RET, KIT, and platelet-derived growth factor receptor-α.
M. Cabanillas, S. Takahashi
semanticscholar   +1 more source

Restaging of differentiated thyroid carcinoma with SPECT/CT after radioiodine therapy

Клиническая и экспериментальная тиреоидология, 2015
Purpose. The purpose of the study was to assess the diagnostic value of SPECT/CT data after radioiodine therapy in comparison with the data of soft tissue neck ultrasonography (US) and computed tomography (CT) in patients with differentiated thyroid ...
Mariya Alekseevna Karalkina, Elena Igorevna Vasilenko, Dmitriy Kirillovich Fomin, Dmitriy Anatol'evich Galushko   +3 more
doaj   +1 more source

Impact of different approaches to calculation of treatment activities on achieved doses in radioiodine therapy of benign thyroid diseases

EJNMMI Physics, 2018
Purpose Radioiodine has been used for the treatment of benign thyroid diseases for over 70 years. However, internationally, there is no common standard for pretherapeutic dosimetry to optimally define the individual therapy activity. Here, we analyze how
Jochen Hammes, Lutz van Heek, Melanie Hohberg, Manuel Reifegerst, Simone Stockter, Markus Dietlein, Markus Wild, Alexander Drzezga, Matthias Schmidt, Carsten Kobe   +9 more
doaj   +1 more source

Silicon-photomultiplier-based PET/CT reduces the minimum detectable activity of iodine-124

Scientific Reports, 2021
The radioiodine isotope pair 124I/131I is used in a theranostic approach for patient-specific treatment of differentiated thyroid cancer. Lesion detectability is notably higher for 124I PET (positron emission tomography) than for 131I gamma camera ...
David Kersting, Walter Jentzen, Pedro Fragoso Costa, Miriam Sraieb, Patrick Sandach, Lale Umutlu, Maurizio Conti, Fadi Zarrad, Christoph Rischpler, Wolfgang Peter Fendler, Ken Herrmann, Manuel Weber   +11 more
doaj   +1 more source

Thyroid and renal function in cats following low-dose radioiodine (111Mbq) therapy.

Journal of Small Animal Practice, 2019
OBJECTIVES To describe the effect of low-dose (111MBq) radioiodine therapy on thyroid and renal function in hyperthyroid cats over a 12-month follow-up period.
N. Finch, J. Stallwood, S. Tasker, A. Hibbert   +3 more
semanticscholar   +1 more source

The role of multikinase inhibitors target therapy in radioiodine-resistant differentiated thyroid cancer

Клиническая и экспериментальная тиреоидология, 2015
About 5-15% of patients with differentiated thyroid cancer (DTC) primary or within follow-up have had distant metastases or inoperable tumor mass that are resistant to radioiodine therapy as well as dramatically deteriorate survival prognosis.
P O Rumyantsev
doaj   +1 more source

Recombinant human thyrotropin in radioiodine diagnostics and radioiodine ablation of patients with well-differentiated thyroid cancer: the first experience in Russia

Эндокринная хирургия, 2018
Background. Traditional endogenous stimulation of thyroid-stimulating hormone (TSH) by means of long-term withdrawal of thyroid hormones for radioiodine diagnostics and radioiodine therapy causes severe hypothyroidism, which worsens patients general well-
Ivan I. Dedov, Pavel O. Rumyantsev, Ksenia S. Nizhegorodova, Konstantin Y. Slashchuk, Valentina S. Yasyuchenya, Marina S. Sheremeta, Michail V. Degtyarev, Larisa V. Nikankina, Galina A. Melnichenko   +8 more
doaj   +1 more source