Two dicarbadodecaborane(12)‐based dual cyclooxygenase‐2/5‐lipoxygenase (COX‐2/5‐LO) inhibitors were 123I‐labeled. Refinement of labeling and formulation conditions and extensive in vitro characterization are presented. Cell uptake studies in COX‐2‐ and 5‐LO‐overexpressing cell lines showed COX‐2‐independent and partly 5‐LO‐dependent uptake.
Jonas Schädlich +11 more
wiley +1 more source
A proposed method for regeneration of neutron producing targets, within an accelerator, by ion sputtering techniques [PDF]
Sputtering electrode system design for regeneration of targets within ...
Alger, D. L., Steinberg, R.
core +1 more source
CXCR4 functions as a potential cancer stem cell‐associated marker linked to chemoresistance in ovarian cancer, and an inhibitor of CXCR4, AMD3100, can enhance the cytotoxic response to cisplatin. Based on these findings, [68Ga]Ga‐Pentixafor positron emission tomography enables selective visualization of CXCR4‐high ovarian cancer, while AMD3100 combined
Lixia Feng +12 more
wiley +1 more source
Aquatic live animal radiotracing studies for ecotoxicological applications : addressing fundamental methodological deficiencies [PDF]
The use of live animal gamma radioisotope tracer techniques in the field of ecotoxicology allows laboratory studies to accurately monitor contaminant biokinetics in real time for an individual organism.
Alquezar +36 more
core +1 more source
Kinetics of sulfate‐ and iron‐dependent anaerobic methane oxidation in freshwater lake sediment
Abstract Anaerobic oxidation of methane (AOM) is a potentially important sink for methane in freshwater sediments. Assessing the contribution of AOM to methane budgets requires an understanding of AOM process kinetics, yet such information remains scarce.
Alina Mostovaya +2 more
wiley +1 more source
Upper Ocean Cycling of Iron South of the Polar Front: Biological Patterns and Processes
Abstract Samples from the upper 300 m along the 52°S band, south of the Antarctic Polar Front in the Atlantic sector of the Southern Ocean, including a 3‐week monitoring of a persistent bloom, were analyzed to advance our understanding of iron cycling and supply to recurrent phytoplankton blooms.
Luis M. Laglera +4 more
wiley +1 more source
Development and Evaluation of an Impedance Cardiographic System to Measure Cardiac Output and Other Cardiac Parameters, 1 July 1968 - 30 June 1969 [PDF]
Impedance cardiographic system to measure cardiac output and cardiovascular ...
Fromm, A. H. L. +3 more
core +1 more source
Serum vitamin B12 from 6 sheep fed a diet containing 0.06 mg cobalt per kg dry matter (DM) was analysed by a radioisotope dilution (RID) technique. The results were compared with values obtained by a microbiological method (Lactobacillus leichmannii - ATCC 7830) specific for "true" vitamin B12.
Mohammed, R., Lamand, M.
openaire +2 more sources
A study of the possible preventive effects of muscular exercises and intermittent venous occlusion on the cardiovascular deconditioning observed after 10 days bed recumbency - Experimental design [PDF]
Experiment designed to study preventive effects of muscular exercises on intermittent venous occlusion on cardiovascular deconditioning observed after 10 days bed ...
Beasley, W. C., Cardus, D., Vogt, F. B.
core +1 more source

