Toward Personalized Theranostics: A Modular PET Platform for Antibody‐Based Imaging and Therapy
This modular, site‐specific antibody platform enables customizable conjugates for PET imaging and therapy. Interchangeable payloads – including radiometals, cytotoxics, and fluorophores – support adaptable, multimodal applications with limited off‐target effects. In vivo, the DFO/DOTAGA bischelate immunoconjugate provided clear tumor delineation in PET/
Delphine Vivier +16 more
wiley +1 more source
Simpler and More Accurate: Weighing the Mercury in Electrolytic Cells by Radiotracer Dilution Method [PDF]
Weight of mercury in electrolytic cell of soda industry is usually measured gravimetrically, which is typical labor work in character. Error sources of the gravimetric method might have come from the fact that some mercury's are usually trapped in the ...
Santoso, S. B. (S) +2 more
core +4 more sources
Abstract Accurate measurements of phytoplankton net primary production (NPP) and calcification are essential for quantifying marine carbon cycling, yet in situ calcification rates remain poorly constrained. We compared 13C‐ and 14C‐based tracer methods for NPP in laboratory cultures of the diatom Chaetoceros tenuissimus and the coccolithophore ...
Chloe L. Smith +4 more
wiley +1 more source
Light dilution via diffusers:enhancing algal productivity [PDF]
Microalgae are promising feedstock for biofuels. The productivity of these microorganisms greatly exceeds that of oil containing agricultural crops, without competing for arable land.
Badby, Luke
core
A novel simple hemoglobin dilution technique to measure hemodialysis vascular access flow [PDF]
Measurement of the vascular access flow rate (Qa) is a widely accepted method for surveillance and predicting access failure. Among current practical methods, the ultrasound dilution technique is standard, but this requires a costly device available in ...
Leelahavanichkul, A. +8 more
core +1 more source
ABSTRACT Gram‐negative (G−) bacterial infections, fueled by intrinsic antibiotic resistance stemming from their unique outer membrane architecture, pose a critical global clinical challenge. This study introduces a pioneering dual‐enzyme‐mimetic nanotherapy based on NaYbF4 nanoparticles (NaYbF4 NPs) that achieves synergistic antibacterial and anti ...
Yuxiang Zhang +6 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Allometric association between in vivo estimation of body composition during growth using deuterium dilution technique and chemical analysis of serial slaughtered pigs [PDF]
The objective of this study was to develop accurate mathematical-statistical functions to estimate body composition of live pigs between 20 and 140 kg weight from total body water (TBWA) determined by the deuterium dilution technique.
Kalm, E. +6 more
core +1 more source
Brine Pool Microbes Enrich Metalliferous Sediments in Salt Giant Basins
Abstract We report the discovery of an extinct deep‐sea brine pool in the Red Sea's Hume Deep, providing evidence that rift‐shoulder pools are ephemeral on millennial timescales, and that the microbially‐enriched metalliferous deposits produced during the pool's active phase persist into the stratigraphic record.
Morgan I. Chakraborty +11 more
wiley +1 more source
Experimental Measurement of Turbulent Diffusion, Initial Dilution and T90
The final disposal of sewage using submarine outfalls has become an actual solution for coastal cities all over the world. In order to get the best results it is necessary to carry out specific studies for the proper design of the outfall.
Edmundo Garcia Agudo +1 more
core +1 more source

