Results 151 to 160 of about 57,593 (318)

Focal Spot, Winter 1975 [PDF]

open access: yes, 1975
https://digitalcommons.wustl.edu/focal_spot_archives/1013/thumbnail ...

core   +1 more source

Three‐Year Follow‐Up of Neoadjuvant Tislelizumab with Chemotherapy in Locally Advanced Gastric and Gastroesophageal Junction Adenocarcinoma: Revealing Cancer‐Associated Fibroblast Heterogeneity Corresponding to PD‐1 Blockade Efficacy

open access: yesAdvanced Science, EarlyView.
Heterogeneous cancer‐associated fibroblasts orchestrate dual immune microenvironments in LAGC. Abstract The potential for immunotherapy in patients with locally advanced gastric cancer (LAGC) is recently confirmed. To report the 3‐year follow‐up data are aimed from a novel clinical trial. This is a prospective single‐arm phase II trial.
Yao Lin   +14 more
wiley   +1 more source

Exploring Interventional Radiology: A Multicentre Study on Saudi Medical and Radiology Technology Students’ Perspectives

open access: yesAdvances in Medical Education and Practice
Shrooq Aldahery,1 Renad Qwader,1 Raghad Talal Asiri,1 Afnan Al-Alfy,1 Lubna Bushara,1 Abdulaziz Qurashi,2 Fahad H Alhazmi,2 Awadia Gareeballah,2 Adnan AS Alahmadi,3 Mohamed Yousef,4 Hanady Osman,4 Walaa Alsharif,2 Khalid M Alshamrani5– 7 1Department of ...
Aldahery S   +12 more
doaj  

Focal Spot, Summer 1997 [PDF]

open access: yes, 1997
https://digitalcommons.wustl.edu/focal_spot_archives/1076/thumbnail ...

core   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han   +10 more
wiley   +1 more source

Focal Spot, Fall 1976 [PDF]

open access: yes, 1976
https://digitalcommons.wustl.edu/focal_spot_archives/1015/thumbnail ...

core   +1 more source

Dysregulation of CircZNF79(5) Modulates YBX1 Stability and Selective Autophagy to Drive Hepatocellular Carcinoma Progression

open access: yesAdvanced Science, EarlyView.
In HCC, circZNF79(5) binds to YBX1 and functions as an oncogene, recruits BRCC36 to remove K63‐linked ubiquitin chains to stabilize YBX1 protein, and promotes HCC progression via the HIF‐1 signaling pathway. Conversely, circZNF79(5) silencing activates the AMPK/mTOR pathway, inducing p62‐mediated selective autophagic degradation of YBX1.
Xueqiang Guo   +20 more
wiley   +1 more source

Foundation Model‐Enabled Multimodal Deep Learning for Prognostic Prediction in Colorectal Cancer with Incomplete Modalities: A Multi‐Institutional Retrospective Study

open access: yesAdvanced Science, EarlyView.
FLARE, a multimodal AI framework, combines pathology slides, radiology scans, and clinical reports to predict colorectal cancer outcomes, even when some tests are missing. Evaluated retrospectively in 1679 patients from four medical centers, it consistently achieved the best prognostic accuracy and clearly separated high‐ and low‐risk groups.
Linhao Qu   +6 more
wiley   +1 more source

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