Results 241 to 250 of about 1,094,433 (306)

NIPAL1 Drives a Metabolic‐Epigenetic Feedback Loop to Promote Lactate‐Mediated Immune Evasion in Esophageal Cancer

Advanced Science, EarlyView.
The study identifies a NIPAL1‐driven metabolic‐epigenetic circuit in esophageal squamous cell carcinoma that promotes glycolysis, lactate accumulation, and H3K18 histone lactylation, forming a self‐sustaining loop that suppresses CD8+ T cell immunity.
Ri‐Xin Chen, Xiao‐Dan Ma, Shui‐Dan Xu, Ao‐Tian Mo, Min‐Hua Deng, Jun‐Han Wu, Wei‐Tao Zhuang, Jin‐Ling Duan, Shu‐Huan Xie, Jin‐Long Lin, Peng Lin, Ji‐Ming Tang, Hai‐Yu Zhou, Xiao‐Song Ben, Gui‐Bin Qiao, Dan Xie   +15 more
wiley   +1 more source

PVNCRF Neurons Regulate Migraine‐Like Allodynia by Activating CRFR2 on Spinal Trigeminal Caudalis Glutamatergic Neurons

Advanced Science, EarlyView.
Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian, Xiao‐Long Wang, Li Yin, Wei Wei, Xue Li, Yao Ge, Zhao‐Xia Xiang, Na Tian, Li‐Juan Chen, Ming‐Wei Ma, Xia Zhang, Xu Jing, Mei‐Yun Wang, Xu‐Feng Xu   +13 more
wiley   +1 more source

Correction: A meta-learning-based robust federated learning for diagnosing lung adenocarcinoma and tuberculosis granulomas. [PDF]

Front Oncol
Chen Y, Liu L, Feng B, Chen Y, Xu J, Lin H, Li K, Chen X, Ke Y, Zhou H, Hu Q, Jin Q, Long W, Li Q, Chen X.   +14 more
europepmc   +1 more source

Legumain Restrains Granuloma Formation by Inhibiting mTORC1/STAT1‐Mediated M1 Macrophage Polarization in Sarcoidosis

Advanced Science, EarlyView.
Legumain (LGMN) is upregulated in macrophages during sarcoid‑like granuloma formation. Macrophage‑derived LGMN binds to integrin αvβ3 and suppresses mTORC1/STAT1 signaling to restrain M1 macrophage polarization. Intratracheal delivery of lipid nanoparticles carrying Lgmn plasmid DNA (pDNA) elevates LGMN expression and effectively attenuates pulmonary ...
Mengyuan Liu, Yueyin Han, Bingbing Xie, Lili Zhu, Wenxiu Xu, Yinzhen Han, Yue Liao, Shuwei Gao, Dingyuan Jiang, Jing Geng, Zhen Li, Yinan Hu, Huaping Dai   +12 more
wiley   +1 more source

Randomized comparison of gamified mobile app-based training versus conventional learning for pneumothorax detection in chest radiographs. [PDF]

BMC Med Educ
Hassan JJ, Boschenriedter C, Amin AT, Wermelskirchen S, Hempel G, Denecke T, Meyer HJ.   +6 more
europepmc   +1 more source

Expert consensus on imaging diagnosis of human infection with avian influenza. [PDF]

Quant Imaging Med Surg
Wang FR, Huang H, Zheng QT, Deng YY, Zheng GP, Liu JZ, Bao XH, Feng F, Huang XP, He YL, Hou WZ, Li X, Liu Q, Liu XY, Lyu SX, Lyu YB, Lin JF, Le XH, Lu YB, Ma W, Luo SH, Peng Y, Shi YX, Song FX, Tang GX, Tong J, Wu JP, Xu CJ, Wang FX, Ji W, Wu LM, Xie RM, Xie ZH, Yan XS, Yang GL, Yang YX, Yuan J, Zhang LG, Zhang QQ, Zhang N, Zhan Y, Zhu ZQ, Li HJ, Lu PX.   +43 more
europepmc   +1 more source

A narrative review of global inequities in access to uterine artery embolisation. [PDF]

CVIR Endovasc
Lojo-Lendoiro S, Heymann G, Moriarty HK, Wojno M, Kashef E, Plotnik A, Kassamali R, Mahnken AH, Fornazari VA, Clements W.   +9 more
europepmc   +1 more source

Context-Aware Sentence Classification of Radiology Reports Using Synthetic Data: Development and Validation Study.

J Med Internet Res
Kikuchi T, Yamagishi Y, Yamamoto K, Akashi T, Mori H, Makimoto H, Kohro T.   +6 more
europepmc   +1 more source

Comparison of stationary digital chest tomosynthesis to portable chest radiographs: A patient study. [PDF]

PLoS One
Wing C, Gunnell ET, Billingsley A, Ahmed U, Inscoe C, Sakthivel M, Hoag B, Pamuklar E, Benefield T, Lu J, Wang X, Zhou O, Lee YZ.   +12 more
europepmc   +1 more source

Proposing Incidental-Reporting and Data System: A classification system for incidental findings in radiology. [PDF]

World J Radiol
Arkoudis NA, Moschovaki-Zeiger O, Koutserimpas C, Lama N, Velonakis G, Filippiadis D, Spiliopoulos S, Kelekis N.   +7 more
europepmc   +1 more source