Results 121 to 130 of about 111,141 (252)

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

open access: yesAdvanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang   +9 more
wiley   +1 more source

Managing Radiology Requests to Support Effective Triage.

open access: yes, 2023
The article discusses how to appropriately manage radiology request in the radiology department to support effective triage. Also cited are the key role played by the lead radiologic technologist or radiology manager in ensuring correct examination ...
Molvin, Lior   +2 more
core  

Transformer‐Based Multitask Framework Integrating Habitat and Deep Learning for Predicting Early Disease Control and Survival in Immunotherapy‐Treated Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
This study developed ECOS‐Net, a transformer‐based multitask framework integrating CT‐derived habitat and 2.5D deep learning features to simultaneously predict early disease control and overall survival in hepatocellular carcinoma patients treated with immune checkpoint inhibitors.
Xiaona Fu   +23 more
wiley   +1 more source

Get The Message : The Utilization and Issues With Abbreviations in Nuclear Medicine

open access: yes, 2022
Introduction: -Abbreviations are commonly used in the nuclear medicine and radiology workplace. They are convenient, time saving and can help the misspelling of words.-Abbreviations can result in miscommunication of findings due to incorrect ...
Meshekow, Jared   +6 more
core  

Transformer‐Based PET/CT Fusion Enables Preoperative Prediction and Prognostic Stratification of Spread Through Air Spaces in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
An eight‐stream 2.5D Transformer integrates complementary PET metabolic and CT morphologic information to estimate spread‐through‐air‐spaces risk before surgery in lung adenocarcinoma. The model generalizes across independent centers, while its continuous risk score independently stratifies progression‐free survival, supporting further prospective ...
Xin‐Yu Zhu   +7 more
wiley   +1 more source

Evolving role of nuclear medicine modalities in the evaluation of renal diseases [PDF]

open access: yes, 2018
Department of Radiology and Imaging, Nicolae Testemitanu State University of Medicine and Pharmacy Chisinau, the Republic of Moldova, The IVth Congress of Radiology and Medical Imaging of the Republic of Moldova with international participation ...
Neelankavil Joel, George
core   +1 more source

Ac-225 radiochemistry through the lens of [225Ac]Ac-DOTA-TATE

open access: yesEJNMMI Radiopharmacy and Chemistry
Background Targeted alpha therapy with Ac-225 showed to be effective in treating metastatic cancers. However, the complex decay chain requires optimized radiolabeling and quality control.
Eline L. Hooijman   +8 more
doaj   +1 more source

Tumor‐Intrinsic HEXB Drives Endothelial‐To‐Mesenchymal Transition and Confers Resistance to Anti‐Angiogenic Therapy in Glioblastoma

open access: yesAdvanced Science, EarlyView.
This study elucidates how glioblastoma tumors develop resistance to anti‐VEGF therapy through endothelial‐to‐mesenchymal transition (Endo‐MT). The researchers identify a novel signaling pathway where tumor‐derived HEXB stabilizes HSP60 to drive this vascular reprogramming.
Tianqi Liu   +13 more
wiley   +1 more source

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