Results 61 to 70 of about 111,141 (252)

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

Resolving and Controlling Silicoaluminophosphate Zeolite Intergrowths and Mixtures

Advanced Science, EarlyView.
Low‐dose electron microscopy enables atomic‐resolution imaging of beam‐sensitive SAPO‐34/18 intergrowths, revealing their stacking sequences and spatial distributions under controlled Si content and SDA ratio. This work establishes a methodology linking controllable synthesis with atomic‐resolution microscopy to investigate structure–property ...
Yuxin Ke, Jiale Feng, Lei Wang, Xiao Chen, Mengmeng Ma, Jiabin Cui, Juan Diwu, Yuman Liu, Fei Wei, Boyuan Shen, Bin Song   +10 more
wiley   +1 more source

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

Digital Twins in Radiology

, 2022
A digital twin is a virtual model developed to accurately reflect a physical thing or a system. In radiology, a digital twin of a radiological device enables developers to test its characteristics, make alterations to the design or materials, and test ...
Filippo Pesapane, Penco, Silvia, Enrico Cassano, Pesapane, Filippo, Cassano, Enrico, Silvia Penco, Nicosia, Luca, Luca Nicosia, Rotili, Anna, Anna Rotili, Cassano E., Pesapane F, Rotili A, Penco S, Nicosia L   +14 more
core   +1 more source

Multitask Deep Learning Model for Predicting Lymph Node Metastasis and Disease‐Free Survival From Cytology Images in Bladder Cancer: A Multicenter Study With Pan‐Cytology Validation

Advanced Science, EarlyView.
Through self‐supervised pretraining and supervised fine‐tuning on large‐scale cytology image datasets, CytoNet predicts lymph node metastasis and survival. Across independent cohorts, this multitask framework demonstrates robust performance, improves risk stratification beyond radiological assessment, and provides interpretable evidence to support ...
Guibin Hong, Fan Jiang, Ye Xie, Xiaowei Huang, Runnan Shen, Yun Wang, Mengyi Zhu, Haoxuan Wang, Hongkun Yang, Yanxiao Nie, Zhen Lin, Rui Chen, Nengtai Ouyang, Tianxin Lin, Shaoxu Wu   +14 more
wiley   +1 more source

Potentials and practical challenges of terbium-161 labeled radiopharmaceuticals

EJNMMI Radiopharmacy and Chemistry
Background Due to promising preclinical studies and clinical case reports, Tb-161 labeled radiopharmaceuticals for targeted radionuclide therapy (TRT) have gained interest.
Carolline M. Ntihabose, Maryana Handula, Amber Piet, Savanne Beekman, Louise van Dalen, Negin Eskandari, Asude Aydogan, Debra Stuurman, Corrina de Ridder, Mark Konijnenberg, Yann Seimbille, Erik de Blois   +11 more
doaj   +1 more source

ESR paper on structured reporting in radiology [PDF]

, 2018
: Structured reporting is emerging as a key element of optimising radiology’s contribution to patient outcomes and ensuring the value of radiologists’ work. It is being developed and supported by many national and international radiology societies, based
Pyatigorskaya, Nadya, Goldberg, S. Nahum, Brady, Adrian P., Gibaud, Bernard, Visser, Jacob J., Neri, Emanuele, Visser, Jacob J.; id_orcid   +6 more
core   +2 more sources

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Liver Imaging Reporting and Data System: an expert consensus statement

Journal of Hepatocellular Carcinoma, 2017
Khaled M Elsayes,1 Ania Z Kielar,2 Michelle M Agrons,3 Janio Szklaruk,1 An Tang,4 Mustafa R Bashir,5 Donald G Mitchell,6 Richard K Do,7 Kathryn J Fowler,8 Victoria Chernyak,9 Claude B Sirlin10 1Department of Diagnostic Radiology, The University of Texas ...
Elsayes KM, Kielar AZ, Agrons MM, Szklaruk J, Tang A, Bashir MR, Mitchell DG, Do RK, Fowler KJ, Chernyak V, Sirlin CB   +10 more
doaj  

BraMARS: An Interpretable Histopathology‐Driven Deep Learning Model for Brain Metastasis Risk Stratification in Surgically Resected Limited‐Stage SCLC

Advanced Science, EarlyView.
This study presents BraMARS, an explainable deep learning model that estimates future brain metastasis risk in surgically resected limited‐stage small‐cell lung cancer using routine H&E‐stained whole‐slide images. By linking model‐attributed spatial histopathology with clinical outcomes and proteomic programs, BraMARS provides a biologically ...
Zijian Yang, Taolue Wang, Shilong Liu, Zicheng Zhang, Yibo Zhang, Fan Yang, Bo Yu, Shuaishuai Gao, Yu Chen, Lin Yang, Meng Zhou   +10 more
wiley   +1 more source