Results 161 to 170 of about 1,796,626 (255)

Transcriptional Profiling of Growth Hormone–Secreting Pituitary Adenoma Stem‐Like Cells: Unveiling the Significant Role of CXCR4 in Tumorigenesis and Clinical Applications

open access: yesMedComm, Volume 7, Issue 9, September 2026.
Growth hormone–secreting pituitary adenomas harbor hPASCs (human pituitary adenoma stem‐like cells). Genetic profiling of hPASCs identified CXCR4 as a significant gene orchestrating a regulatory network in the self‐renewal and differentiation of hPASCs, as well as the modulation of tumor cells and the microenvironment.
LinHao Yuan   +11 more
wiley   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

open access: yesMedicinal Research Reviews, Volume 46, Issue 5, Page 1362-1389, September 2026.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg   +2 more
wiley   +1 more source

Prostate Cancer Development, Progression, and Therapy

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin   +9 more
wiley   +1 more source

Dose modeling of superficial brachytherapy applicator geometries using multiple radioisotopes

open access: yesMedical Physics, Volume 53, Issue 9, September 2026.
Abstract Background Superficial brachytherapy enables localized dose delivery for superficial cutaneous lesions, but conventional applicators may be limited in treating extended, irregular, or curved surfaces. Geometric constraints, gaps or overlaps between adjacent applicators, and placement‐related uncertainties can reduce dose uniformity ...
Jin Jegal   +5 more
wiley   +1 more source

Experimental activation assessment of open‐type yoke in a PET cyclotron by non‐destructive/destructive γ‐ray measurement approaches

open access: yesMedical Physics, Volume 53, Issue 9, September 2026.
Abstract Background During decommissioning of positron emission tomography (PET) cyclotron facilities, metallic components—including the iron yoke—are typically classified as radioactive waste, incurring substantial disposal costs. In contrast to concrete, standardized decommissioning procedures for metallic components have not yet been established ...
Go Yoshida   +14 more
wiley   +1 more source

Roadmap for the implementation of particle minibeam therapy

open access: yesMedical Physics, Volume 53, Issue 9, September 2026.
Abstract Particle minibeam therapy (PMBT) has emerged as an advanced modality within spatially fractionated radiation therapy, using the physical properties of protons, ions, and electrons to achieve superior normal tissue sparing whilst preserving spatial dose distribution at depths that are unachievable in conventional kV or MV X‐rays.
Reem Ahmad   +32 more
wiley   +1 more source

Home - About - Disclaimer - Privacy