Non-invasive radionuclide imaging of trace metal trafficking in health and disease: "PET metallomics". [PDF]
RSC Chem Biol, 2022 Firth G +8 more
europepmc +1 more source
Medical Physics, EarlyView.Abstract Background Intensity‐modulated proton therapy (IMPT) holds promise for improving outcomes in head‐and‐neck cancer (HNC) patients by enhancing organ‐at‐risk (OAR) sparing. A key challenge in IMPT is ensuring an accurate dose delivery at the distal edge of the tumor, where the steep dose gradients make treatment precision highly sensitive to ...
Brian Zapien‐Campos +5 more
wiley +1 more source
Semi-Supervised Learning for Dose Prediction in Targeted Radionuclide: A Synthetic Data Study [PDF]
arXivTargeted Radionuclide Therapy (TRT) is a modern strategy in radiation oncology that aims to administer a potent radiation dose specifically to cancer cells using cancer-targeting radiopharmaceuticals. Accurate radiation dose estimation tailored to individual patients is crucial.
arxiv
Medical Physics, EarlyView.Abstract Purpose This work provides the first two clinical test cases for commissioning electronic brachytherapy (eBT) model‐based dose calculation algorithms (MBDCAs) for skin irradiation using surface applicators. Acquisition and Validation Methods The test cases utilize the INTRABEAM 30 mm surface applicator.
Iymad R. Mansour +12 more
wiley +1 more source
David versus Goliath: Radiotheranostic nanomedicine as a weapon against melanoma
Cancer Treatment and Research Communications, 2021 Malignant melanoma (MM), especially when diagnosed at an advanced stage, still represents a challenge for physicians. In recent years, immune check point inhibitors (ICI) have thoroughly changed MM landscape, although only 20–40% of MM patients respond ...
Luca Filippi +2 more
doaj
Development of a high-resolution and high efficiency Single Photon detector for studying cardiovascular diseases in mice [PDF]
arXiv, 2019 SPECT systems using pinhole apertures permit radiolabeled molecular distributions to be imaged in vivo in small animals. Nevertheless studying cardiovascular diseases by means of small animal models is very challenging. Specifically, submillimeter spatial resolution, good energy resolution and high sensitivity are required. We designed what we consider
arxiv
Generation of Digital Brain Phantom for Machine Learning Application of Dopamine Transporter Radionuclide Imaging. [PDF]
Diagnostics (Basel), 2022 Shao W +5 more
europepmc +1 more source
The 10% Rule in Sentinel Node Biopsy: Is Removal of All Threshold Nodes Necessary?
Otolaryngology–Head and Neck Surgery, EarlyView.Abstract Objective Sentinel lymph node biopsy (SLNB) procedures have been guided by the “10% rule,” which stipulates that any lymph node (LN) with gamma probe activity (GPA) measured at 10% of the most radioactive sentinel lymph nodes (SLNs) should be excised.
Jake Langlie +5 more
wiley +1 more source
ChemistryOpen, EarlyView.Several new N,O‐ligands containing the 1,2,4‐triazine‐3‐carboxamide chelating group were synthesized and evaluated as actinide selective extracting agents for reprocessing spent nuclear fuels. The likely complexes formed with lanthanides were investigated by 1H NMR titrations and DFT calculations.
Andrey V. Zaytsev +6 more
wiley +1 more source
The role of 99mTc-Ubiquicidin (UBI) and 99mTc-IgG scintigraphies in diagnosis of acute appendicitis: A preliminary result [PDF]
, 2014 Introduction: Appendicitis is one of the most common surgical emergencies. In spite of the relatively high rate of negative appendectomy, as a result of miss diagnosis, uncertainty of diagnosis still continues to challenge physicians.
Assadi, M. +6 more
core