Results 81 to 90 of about 1,796,626 (255)

Radionuclide Imaging

Journal of the American College of Cardiology, 2008
Despite primary and secondary prevention, serious cardiovascular events such as unstable angina or myocardial infarction still account for one-third of all deaths worldwide. Therefore, identifying individual patients with vulnerable plaques at high risk for plaque rupture is a central challenge in cardiovascular medicine. Several noninvasive techniques,
Langer, Harald F., Haubner, Roland, Pichler, Bernd J., Gawaz, Meinrad   +3 more
openaire   +2 more sources

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet, Klas Petersson, Marc C. Huisman, C. Willemien Menke‐van der Houven van Oordt, Iris H. C. Miedema, Andrea Thiele, Ghazal Montaseri, Alejandro Pérez‐Pitarch, David Busse   +8 more
wiley   +1 more source

RADIONUCLIDE QUANTITATIVE IN ASSESSMENT OF MYOCARDIAL BLOOD FLOW

Бюллетень сибирской медицины, 2013
The aim of this study were to develop a radionuclide method for quantitative estimation of the myocardial blood flow (MBF). Twelve patients with suspected coronary artery disease underwent both Tc-99mmethoxyisobutylisonitrile (MIBI) imaging and coronary ...
N. G. Krivonogov, S. M. Minin, A. L. Krylov, Yu. B. Lishmanov   +3 more
doaj   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

MODERN view On x-ray DIAGNOSIS OF CARDIOVASCULAR DISEASES (REVIEW)

Сибирский научный медицинский журнал, 2019
According to the forecasts of the World Health Organization, cardiovascular diseases will remain the main cause of death of the world population for several decades.
A. V. Anikina
doaj   +1 more source

Radionuclide Imaging of Heart-Brain Connections. [PDF]

Cardiol Clin, 2023
Abohashem S, Grewal SS, Tawakol A, Osborne MT.   +3 more
europepmc   +1 more source

Boron‐embedded multifunctional nanoplatform toward potential combined boron neutron capture therapy and immunomodulation in glioma

Smart Molecules, EarlyView.
A brain‐targeting multifunctional nanoplatform (DM&Ce6@COF‐Ang) was engineered by employing boron‐enriched APTES‐COF‐1 as both the therapeutic boron agent and the nanocarrier co‐delivery of DMXAA and Ce6. This nanoplatform achieved synergistic tumor‐specific boron delivery, real‐time pharmacokinetic monitoring, and immunomodulation.
Yiming Liu, Xuejian Wang, Bangjian Li, Kun Shao, Jianlong Su, Yang Wang, Lin Cheng, Zhihao Wu, JinRong Li, Guanyi Zhang, Xu Wang, Yuxuan Zhang, Yuanhao Liu, Guangzhe Li   +13 more
wiley   +1 more source

NIS-Centered Reporter Gene Imaging and Radionuclide-Integrated Nanoplatforms for Quantitative Tracking of Immune Cell Therapy in Oncology and Inflammatory Disease Models

Pharmaceuticals
Cell-based immunotherapies require noninvasive tools that can quantify the migration, biodistribution, and persistence of administered immune cells.
Sang Bong Lee
doaj   +1 more source

Current Status of Radionuclide Imaging of Transthyretin Cardiac Amyloidosis. [PDF]

Cardiol Clin, 2023
Waheed A, Dorbala S.
europepmc   +1 more source

Radionuclide Imaging of Cardiac Device Infection

, 2017
Purpose of Review: Accurate diagnosis of cardiac device infection is critical for clinical decision-making and represents a challenge for current diagnostic methods.
Gaudieri V., Assante R., Acampa W., Cantoni V., Zampella E., Nappi C., Green R.   +6 more
core   +1 more source