Results 101 to 110 of about 58,392 (301)

Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. [PDF]

, 2016
OBJECTIVE: The authors have conjugated chelating agents (DOTA and NODAGA) with a peptide (pituitary adenylate cyclase-activating peptide [PACAP] analogue) that has a high affinity for VPAC1 receptors expressed on cancer cells.
Chen, Chang-Po, Kumar, Pardeep, Mehta, Neil, Paudyal, Bishnuhari, Thakur, Mathew L., Tripathi, Sushil Kumar, Wickstrom, Eric   +6 more
core   +2 more sources

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Prostate Cancer Theranostics – Current Evidence and Future Considerations: a Brief Overview

Acta Clinica Croatica
Despite initial response to androgen inhibition, metastatic prostate cancer is invariably an incurable disease. New agents with different mechanisms of action are needed that are capable of producing clinical benefit and prolonging survival.
Antonela Njavro, Jure Murgić, Blanka Jakšić, Marin Prpić, Angela Prgomet Sečan, Dražen Huić, Dinko Franceschi, Ana Fröbe   +7 more
doaj   +1 more source

188Re(V) Nitrido Radiopharmaceuticals for Radionuclide Therapy

Pharmaceuticals, 2017
The favorable nuclear properties of rhenium-188 for therapeutic application are described, together with new methods for the preparation of high yield and stable 188Re radiopharmaceuticals characterized by the presence of the nitride rhenium core in ...
Alessandra Boschi, Petra Martini, Licia Uccelli   +2 more
doaj   +1 more source

Noninvasive PET Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering [PDF]

, 2016
Transplantation of human muscle precursor cells (hMPCs) is envisioned for the treatment of various muscle diseases. However, a feasible noninvasive tool to monitor cell survival, migration, and integration into the host tissue is still missing. METHODS:
Ametamey, Simon M., Betzel, Thomas, Dinulovic, Ivana, Eberli, Daniel, Handschin, Christoph, Haralampieva, Deana, Krämer, Stefanie D., Salemi, Souzan, Schibli, Roger, Stoelting, Meline, Sulser, Tullio   +10 more
core   +2 more sources

Update on radionuclide therapy in oncology.

Oncology letters, 2017
Unstable isotopes and their capacity to emit ionizing radiation have been employed in clinical practice not only for diagnostic, but also for therapeutic purposes, with significant contribution in several fields of medicine and primarily in the management of oncologic patients.
Nitipir, Cornelia, Niculae, Dana, Orlov, Cristina, Barbu, Maria Alexandra, Popescu, Bogdan, Popa, Ana Maria, Pantea, Anca Mihaela Stoian, Stanciu, Adina Elena, Galateanu, Bianca, Ginghina, Octav, Papadakis, Georgios Z., Izotov, Boris N., Spandidos, Demetrios A., Tsatsakis, Aristides M., Negrei, Carolina   +14 more
openaire   +2 more sources

A minimal physiologically‐based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti‐LAG‐3 monoclonal antibody

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 460-473, March 2025.
Abstract In oncology drug development, measuring drug concentrations at the tumor site and at the targeted receptor remains an ongoing challenge. Positron emission tomography (PET)‐imaging is a promising noninvasive method to quantify intratumor exposure of a radiolabeled drug (biodistribution data) and target saturation by treatment doses in vivo ...
Robin Michelet, Klas Petersson, Marc C. Huisman, C. Willemien Menke‐van der Houven van Oordt, Iris H. C. Miedema, Andrea Thiele, Ghazal Montaseri, Alejandro Pérez‐Pitarch, David Busse   +8 more
wiley   +1 more source

Early Diagnosis of Alzheimer's disease by NIRF Spectroscopy and Nuclear Medicine-v.4.0 [PDF]

, 2011
There is an urgent need for the early detection of diseases such as Alzheimer’s (AD) and Cancers in order to enable their successful treatment. Cancer is the second major cause of death after Heart Disease, and AD is the third major cause of death
I Baianu
core   +1 more source

Radiobiological Assessment of Targeted Radionuclide Therapy with [177Lu]Lu-PSMA-I&T in 2D vs. 3D Cell Culture Models [PDF]

, 2023
Julia Raitanen, Bernadette Barta, H. Fuchs, Marcus Hacker, Theresa Balber, Dietmar Georg, Markus Mitterhauser   +6 more
openalex   +1 more source

Narrow‐Diameter Tubular One‐Dimensional van der Waals Heterostructures

Small, EarlyView.
Narrow 1D van der Waals heterostructures are formed by template‐assisted growth of single‐layer lutetium halide nanotubes, down to ≈1 nm diameter, inside single‐walled carbon nanotubes. The role of the halide size on nanotube formation is elucidated by means of aberration‐corrected electron microscopy and image simulations, while the electronic ...
Elzbieta Pach, Magdalena Kierkowicz, Mert Kurttepeli, Carlos Frontera, Costanza Borghesi, Giacomo Giorgi, Riccardo Rurali, Sara Bals, Gustaaf Van Tendeloo, Gerard Tobías‐Rossell, Belén Ballesteros   +10 more
wiley   +1 more source