Results 111 to 120 of about 58,087 (312)
188Re(V) Nitrido Radiopharmaceuticals for Radionuclide Therapy
Pharmaceuticals, 2017 The favorable nuclear properties of rhenium-188 for therapeutic application are described, together with new methods for the preparation of high yield and stable 188Re radiopharmaceuticals characterized by the presence of the nitride rhenium core in ...
Alessandra Boschi +2 more
doaj +1 more source
Corrin Ring Modification in Peptide Drug Development – a Brief History of “Corrination”
ChemMedChem, EarlyView.This review highlights the applications of vitamin B12 conjugation (“corrination”) to peptides in the field of peptide‐based therapeutics, focusing on improved physio‐chemical properties, targeted/localized drug delivery, and enhanced oral bioavailability.
Nancy Cham, Robert P. Doyle
wiley +1 more source
Quantitative imaging for targeted radionuclide therapy dosimetry : technical review [PDF]
, 2017 Targeted radionuclide therapy (TRT) is a promising technique for cancer therapy. However, in order to deliver the required dose to the tumor, minimize potential toxicity in normal organs, as well as monitor therapeutic effects, it is important to assess ...
Ao, Edwin CI +5 more
core +2 more sources
Radionuclide-labelled nanoparticles for cancer combination therapy: a review
Journal of NanobiotechnologyRadionuclide therapy (RT) is widely used to advanced local cancers. However, its therapeutic efficacy is limited to the radiation resistance of cancer cells.
Na Sun, Tao Wang, Song Zhang
doaj +1 more source
Prostate Cancer Theranostics – Current Evidence and Future Considerations: a Brief Overview
Acta Clinica CroaticaDespite initial response to androgen inhibition, metastatic prostate cancer is invariably an incurable disease. New agents with different mechanisms of action are needed that are capable of producing clinical benefit and prolonging survival.
Antonela Njavro +7 more
doaj +1 more source
An Efficient Solid‐Phase Synthetic Approach to Prepare TACN‐Functionalized Peptides
Chemistry–Methods, EarlyView.By recruiting fluorescent dye NBD as a protecting group, Bis‐NBD‐NO1A is developed as a universal building block to functionalize peptides with TACN derivatives via SPPS. The protection of TACN with NBD becomes the first example to functionalize TACN in a controllable manner. The colour‐guided deprotection of NBD enables further elaborations of TACN as
Yik‐Hoi Yeung +8 more
wiley +1 more source
Frontiers of Synchrotron Methods for Actinide Science
Chemistry–Methods, EarlyView.This article explores the application of synchrotron radiation techniques ‐ XAS, XES, HERFD, RIXS, and XRD ‐ to investigate actinide materials. It provides insights into electronic structures, oxidation states, and phase transitions, emphasizing the transformative role of these techniques in advancing nuclear materials research, environmental safety ...
Damien Prieur +7 more
wiley +1 more source
[177Lu-DOTA0,Tyr3]octreotate for somatostatin receptor-targeted radionuclide therapy [PDF]
, 2001 Marion de Jong +10 more
openalex +2 more sources
How to explain the sensitivity of DNA double-strand breaks yield to 125I position? [PDF]
International Journal of Radiation Biology, 2022, 99 (1),
pp.103-108Purpose: Auger emitters exhibit interesting features due to their emission of a cascade of short-range Auger electrons. Maximum DNA breakage efficacy is achieved when decays occur near DNA. Studies of double-strand breaks (DSBs) yields in plasmids revealed cutoff distances from DNA axis of 10.5-12 {\AA}, beyond which the mechanism of DSBs moves from ...
arxiv +1 more source