Results 21 to 30 of about 30,778 (256)

Analysis of lncRNA and mRNA Transcriptomes Expression in Thyroid Cancer Tissues Among Patients With Exposure of Medical Occupational Radiation

Dose-Response, 2019
Background: Occupational exposure of radiation among medical radiation workers contributes to the subsequent increased risk of thyroid cancer. Long noncoding RNAs (lncRNAs) are emerging as important regulators of cancer biology.
Feng Shi, Ying Liu, Min Li, Peng Wen, Qiu Qin Qian, Yibin Fan, Ruixue Huang   +6 more
doaj   +1 more source

Peptide Receptor Radionuclide Therapy

The Journal of Clinical Endocrinology & Metabolism, 2022
Abstract The concept of using a targeting molecule labeled with a diagnostic radionuclide for using positron emission tomography or single photon emission computed tomography imaging with the potential to demonstrate that tumoricidal radiation can be delivered to tumoral sites by administration of the same or a similar targeting molecule
Johannes Hofland, Tessa Brabander, Frederik A Verburg, Richard A Feelders, Wouter W de Herder   +4 more
openaire   +3 more sources

Nephrotoxicity after radionuclide therapies

Translational Oncology, 2022
Radioligand therapies have opened new treatment avenues for cancer patients. They offer precise tumor targeting with a favorable efficacy-to-toxicity profile. Specifically, the kidneys, once regarded as the critical organ for radiation toxicity, also show excellent tolerance to radiation doses as high as 50-60 Gy in selected cases.
Ashwin Singh Parihar, Sejal Chopra, Vikas Prasad   +2 more
openaire   +3 more sources

PERSONALIZED APPROACH TO THYROTOXICOSIS TREATMENT: THE HISTORY OF DOSIMETRIC CONCEPTS DEVELOPMENT

Вестник рентгенологии и радиологии, 2017
In recent decade, nuclear medicine demonstrates a tendency towards improvement of dosimetry approaches to radionuclide therapy. Historically there were developed several methods for calculating effective therapeutic activity: prescription of standard ...
P. O. Rumyantsev, A. A. Trukhin, M. V. Degtyarev   +2 more
doaj   +1 more source

Potential application of lutetium-177-labeled prostate-specific membrane antigen-617 radioligand therapy for metastatic castration-resistant prostate cancer in a limited resource environment: Initial clinical experience after 2 years

World Journal of Nuclear Medicine, 2020
In recent years, lutetium-177 (177Lu)-labeled prostate-specific membrane antigen (PSMA)-617 has become a promising new therapeutic agent in patients with metastatic castration-resistant prostate cancer (mCRPC).
Majid Assadi, Samira Rezaei, Esmail Jafari, Seyed Javad Rekabpour, Mohammad Ravanbod, Farshad Zohrabi, AbdulLatif Amini, Saeid Keshmiri, Habibollah Dadgar, Hojjat Ahmadzadehfar   +9 more
doaj   +1 more source

Targeted radionuclide therapy [PDF]

Medical Physics, 2008
Targeted radionuclide therapy (TRT) seeks molecular and functional targets within patient tumor sites. A number of agents have been constructed and labeled with beta, alpha, and Auger emitters. Radionuclide carriers spanning a broad range of sizes; e.g., antibodies, liposomes, and constructs such as nanoparticles have been used in these studies. Uptake,
Lawrence E. Williams, Gerald L. DeNardo, Ruby F. Meredith   +2 more
openaire   +3 more sources

Evaluation of myocardial perfusion and function in patients with asymptomatic beta-thalassemia major using myocardial gated single-photon-emission computed tomography

World Journal of Nuclear Medicine, 2021
This study was conducted to evaluate the cardiac perfusion and function of patients with beta-thalassemia major (TM) using 99mTc-MIBI cardiac gated single-photon-emission computed tomography (SPECT) and to compare the obtained indices with ...
Abdolmajid Omrani, Parivash Rahimzadeh, Ali Aba, Esmail Jafari, Abdullatif Amini, Majid Assadi   +5 more
doaj   +1 more source

Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions

Angewandte Chemie, EarlyView.
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan, Parrish Evers, Elexa Scott, John Paul Pezacki   +3 more
wiley   +2 more sources

Tumor microenvironment-responsive precise delivery nanocarrier potentiating synchronous radionuclide therapy and chemotherapy against cancer. [PDF]

J Nanobiotechnology
An J, Zhou Q, Chu K, Chen S, Niu C, Zhang W, Gao J, Li M, Cao J, Lv J, Zhang D, Wu Z, Li S, Wei H.   +13 more
europepmc   +3 more sources

Radiolabeled nanomaterial for cancer diagnostics and therapeutics: principles and concepts

Cancer Nanotechnology, 2023
In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora of applications in biology and medicine.
Muskan Goel, Yuri Mackeyev, Sunil Krishnan   +2 more
doaj   +1 more source