Results 31 to 40 of about 54,960 (249)

PERSONALIZED APPROACH TO THYROTOXICOSIS TREATMENT: THE HISTORY OF DOSIMETRIC CONCEPTS DEVELOPMENT

open access: yesВестник рентгенологии и радиологии, 2017
In recent decade, nuclear medicine demonstrates a tendency towards improvement of dosimetry approaches to radionuclide therapy. Historically there were developed several methods for calculating effective therapeutic activity: prescription of standard ...
P. O. Rumyantsev   +2 more
doaj   +1 more source

Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma [PDF]

open access: yes, 2014
The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical ...
Babich, John   +5 more
core   +1 more source

Stem Cell Imaging: Tools to Improve Cell Delivery and Viability. [PDF]

open access: yes, 2016
Stem cell therapy (SCT) has shown very promising preclinical results in a variety of regenerative medicine applications. Nevertheless, the complete utility of this technology remains unrealized. Imaging is a potent tool used in multiple stages of SCT and
Jokerst, Jesse V, Wang, Junxin
core   +3 more sources

Preclinical animal research on therapy dosimetry with dual isotopes [PDF]

open access: yes, 2011
Preclinical research into radionuclide therapies based on radiation dosimetry will enable the use of any LET-equivalent radionuclide. Radiation dose and dose rate have significant influence on dose effects in the tumour depending on its radiation ...
Mark W. Konijnenberg, Marion de Jong
core   +4 more sources

Targeted radionuclide therapy [PDF]

open access: yesMedical Physics, 2008
Targeted radionuclide therapy (TRT) seeks molecular and functional targets within patient tumor sites. A number of agents have been constructed and labeled with beta, alpha, and Auger emitters. Radionuclide carriers spanning a broad range of sizes; e.g., antibodies, liposomes, and constructs such as nanoparticles have been used in these studies. Uptake,
Lawrence E. Williams   +2 more
openaire   +3 more sources

Potential application of lutetium-177-labeled prostate-specific membrane antigen-617 radioligand therapy for metastatic castration-resistant prostate cancer in a limited resource environment: Initial clinical experience after 2 years

open access: yesWorld Journal of Nuclear Medicine, 2020
In recent years, lutetium-177 (177Lu)-labeled prostate-specific membrane antigen (PSMA)-617 has become a promising new therapeutic agent in patients with metastatic castration-resistant prostate cancer (mCRPC).
Majid Assadi   +9 more
doaj   +1 more source

Evaluation of myocardial perfusion and function in patients with asymptomatic beta-thalassemia major using myocardial gated single-photon-emission computed tomography

open access: yesWorld Journal of Nuclear Medicine, 2021
This study was conducted to evaluate the cardiac perfusion and function of patients with beta-thalassemia major (TM) using 99mTc-MIBI cardiac gated single-photon-emission computed tomography (SPECT) and to compare the obtained indices with ...
Abdolmajid Omrani   +5 more
doaj   +1 more source

PEPTIDE BASED TARGETED RADIONUCLIDE THERAPIES; SCIENCE BEHIND THE SUCCESS.

open access: yesJournal of Cancer and Allied Specialties, 2016
The radionuclide therapies for solid and liquid malignancies are emerging field nowadays. The targeted radionuclide therapies have been in use since 1945.
Mohammed H Al Rowaily   +4 more
doaj   +1 more source

Radiolabeled nanomaterial for cancer diagnostics and therapeutics: principles and concepts

open access: yesCancer Nanotechnology, 2023
In the last three decades, radiopharmaceuticals have proven their effectiveness for cancer diagnosis and therapy. In parallel, the advances in nanotechnology have fueled a plethora of applications in biology and medicine.
Muskan Goel   +2 more
doaj   +1 more source

Continuing Nuclear Data Research for Production of Accelerator-Based Novel Radionuclides for Medical Use: A Mini-Review

open access: yesFrontiers in Physics, 2021
Nuclear data are important for production and medical application of a radionuclide. This brief review concentrates on nuclear reaction cross-section data.
Syed M. Qaim   +3 more
doaj   +1 more source

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