Results 1 to 10 of about 3,528,989 (183)

212Pb in targeted radionuclide therapy: a review [PDF]

open access: yesEJNMMI Radiopharmacy and Chemistry
Background The selective delivery of α-emitting radionuclides is emerging as a highly effective form of cancer therapy. With a short range and high cytotoxicity, α-particles can selectively kill cancerous cells whilst minimising harm to surrounding ...
Jarred Michael Scaffidi-Muta   +1 more
doaj   +4 more sources

Radionuclides for Targeted Therapy: Physical Properties

open access: yesMolecules, 2022
A search in PubMed revealed that 72 radionuclides have been considered for molecular or functional targeted radionuclide therapy. As radionuclide therapies increase in number and variations, it is important to understand the role of the radionuclide and ...
Caroline Stokke   +2 more
doaj   +7 more sources

Introduction to radiobiology of targeted radionuclide therapy [PDF]

open access: yesFrontiers in Medicine, 2015
During the last decades, new radionuclide-based targeted therapies have emerged as efficient tools for cancer treatment. Targeted radionuclide therapies (TRT) are based on a multidisciplinary approach that involves the cooperation of specialists in ...
Jean-Pierre ePOUGET   +6 more
doaj   +6 more sources

Clinical Advances and Perspectives in Targeted Radionuclide Therapy [PDF]

open access: yesPharmaceutics, 2023
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine subspecialty. For many decades, treatment with radionuclides has been mainly restricted to the use of iodine-131 in thyroid disorders.
Nicolas Lepareur   +3 more
doaj   +6 more sources

Bismuth-213 for Targeted Radionuclide Therapy: From Atom to Bedside

open access: yesPharmaceutics, 2021
In contrast to external high energy photon or proton therapy, targeted radionuclide therapy (TRNT) is a systemic cancer treatment allowing targeted irradiation of a primary tumor and all its metastases, resulting in less collateral damage to normal ...
Stephen Ahenkorah   +7 more
doaj   +3 more sources

Combination Therapy, a Promising Approach to Enhance the Efficacy of Radionuclide and Targeted Radionuclide Therapy of Prostate and Breast Cancer

open access: yesPharmaceutics, 2021
In recent years, radionuclide therapy (RT) and targeted radionuclide therapy (TRT) have gained great interest in cancer treatment. This is due to promising results obtained in both preclinical and clinical studies.
Tyrillshall S. T. Damiana   +1 more
doaj   +3 more sources

A brief overview of targeted radionuclide therapy trials in 2022 [PDF]

open access: yesFrontiers in Nuclear Medicine, 2023
There is a growing use of radionuclide therapy for the medical care of oncology patients, where radioactive pharmaceuticals are used to target and treat various cancer types.
Aidan Healy   +3 more
doaj   +2 more sources

FAP-Targeted Radionuclide Therapy: Mechanisms, Clinical Applications, and Combination Strategies [PDF]

open access: yesBiomedicines
The fibroblast activation protein (FAP) has emerged as a compelling theranostic target because it is highly expressed in the tumour microenvironment of many solid malignancies, predominantly on cancer-associated fibroblasts and, in selected tumour types,
Ayça Arçay Öztürk   +3 more
doaj   +2 more sources

Targeted Radionuclide Therapy Activates Prodrugs for Treating Metastasis [PDF]

open access: yesACS Central Science
Zhibin Guo   +8 more
doaj   +2 more sources

Radiometals in Imaging and Therapy: Highlighting Two Decades of Research

open access: yesPharmaceuticals, 2023
The present article highlights the important progress made in the last two decades in the fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based positron emission tomography, single photon emission computerized tomography,
Shalini Sharma, Mukesh K. Pandey
doaj   +1 more source

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