212Pb in targeted radionuclide therapy: a review [PDF]
EJNMMI Radiopharmacy and ChemistryBackground The selective delivery of α-emitting radionuclides is emerging as a highly effective form of cancer therapy. With a short range and high cytotoxicity, α-particles can selectively kill cancerous cells whilst minimising harm to surrounding ...
Jarred Michael Scaffidi-Muta +1 more
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Clinical Advances and Perspectives in Targeted Radionuclide Therapy [PDF]
Pharmaceutics, 2023 Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine subspecialty. For many decades, treatment with radionuclides has been mainly restricted to the use of iodine-131 in thyroid disorders.
Nicolas Lepareur +3 more
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Radionuclides for Targeted Therapy: Physical Properties
Molecules, 2022 A search in PubMed revealed that 72 radionuclides have been considered for molecular or functional targeted radionuclide therapy. As radionuclide therapies increase in number and variations, it is important to understand the role of the radionuclide and ...
Caroline Stokke +2 more
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Introduction to radiobiology of targeted radionuclide therapy [PDF]
Frontiers in Medicine, 2015 During the last decades, new radionuclide-based targeted therapies have emerged as efficient tools for cancer treatment. Targeted radionuclide therapies (TRT) are based on a multidisciplinary approach that involves the cooperation of specialists in ...
Jean-Pierre ePOUGET +6 more
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Prospects in folate receptor-targeted radionuclide therapy [PDF]
Frontiers in Oncology, 2013 Targeted radionuclide therapy is based on systemic application of particle-emitting radiopharmaceuticals which are directed towards a specific tumor-associated target. Accumulation of the radiopharmaceutical in targeted cancer cells results in high doses
Cristina eMüller +2 more
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A brief overview of targeted radionuclide therapy trials in 2022 [PDF]
Frontiers in Nuclear Medicine, 2023 There is a growing use of radionuclide therapy for the medical care of oncology patients, where radioactive pharmaceuticals are used to target and treat various cancer types.
Aidan Healy +3 more
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Targeted Radionuclide Therapy of Cancer and Infections. [PDF]
Int J Mol Sci, 2023 Targeted radionuclide therapy (TRT) has been burgeoning worldwide, with several radiopharmaceuticals for the treatment of metastatic cancers being approved for clinical use [...]
van der Wal BCH, Dadachova E.
europepmc +4 more sources
Targeted radionuclide therapy in endocrine-related cancers: advances in the last decade [PDF]
Frontiers in Endocrinology, 2023 Targeted radionuclide therapy plays an increasingly important role in managing endocrine-related tumors and significantly advances the therapeutic landscape for patients with these diseases.
Taymeyah Al-Toubah +4 more
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DNA Repair Inhibitors: Potential Targets and Partners for Targeted Radionuclide Therapy [PDF]
Pharmaceutics, 2023 The present review aims to explore the potential targets/partners for future targeted radionuclide therapy (TRT) strategies, wherein cancer cells often are not killed effectively, despite receiving a high average tumor radiation dose.
Honoka Obata +2 more
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Editorial for the Special Issue “Molecular Biology in Targeted Radionuclide Therapy Radiopharmaceutical Design” [PDF]
Current Issues in Molecular BiologyTargeted radionuclide therapy (TRT) is gaining wide and rapid acceptance in clinical practice as it can deliver alpha or beta irradiation to a tumor-associated target which may be present in the tumor cell itself or in the microenvironment [...]
Carlo Aprile +3 more
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