Prostate-specific membrane antigen (PSMA)-targeted radioligand therapy is a validated treatment option for patients with advanced prostate cancer. Although PSMA expression is not limited to prostate tissue, little is known about its relevance to other ...
John Prior +8 more
doaj +1 more source
Evaluation of melanin-targeted radiotherapy in combination with radiosensitizing drugs for the treatment of melanoma [PDF]
The incidence of malignant melanoma is rising faster than that of any other cancer in the United States. An [131I]-labeled benzamide - [131I]MIP-1145 - selectively targets melanin, reduces melanoma tumor burden and increases survival in preclinical ...
Babich, John +5 more
core +1 more source
Immune Checkpoint Inhibitor-Mediated Cancer Theranostics with Radiolabeled Anti-Granzyme B Peptide
Although immune checkpoint inhibitors (ICI) have revolutionized cancer management, patient response can be heterogeneous, and the development of ICI resistance is increasingly reported.
Carolina de Aguiar Ferreira +7 more
doaj +1 more source
Therapeutic sequences in patients with grade 1−2 neuroendocrine tumors (NET): an observational multicenter study from the ELIOS group [PDF]
Purpose: Many different treatments are suggested by guidelines to treat grade 1−2 (G1−G2) neuroendocrine tumors (NET). However, a precise therapeutic algorithm has not yet been established.
Badalamenti, G. +17 more
core +1 more source
New developments in the experimental data for charged particle production of medical radioisotopes [PDF]
The goal of the present work is to give a review of developments achieved experimentally in the field of nuclear data for medically important radioisotopes in the last three years.
Ditrói, F. +3 more
core +2 more sources
Nuclear data are important for production and medical application of a radionuclide. This brief review concentrates on nuclear reaction cross-section data.
Syed M. Qaim +3 more
doaj +1 more source
Stem Cell Imaging: Tools to Improve Cell Delivery and Viability. [PDF]
Stem cell therapy (SCT) has shown very promising preclinical results in a variety of regenerative medicine applications. Nevertheless, the complete utility of this technology remains unrealized. Imaging is a potent tool used in multiple stages of SCT and
Jokerst, Jesse V, Wang, Junxin
core +3 more sources
Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy
The precise delivery of cytotoxic radiation to cancer cells through the combination of a specific targeting vector with a radionuclide for targeted radionuclide therapy (TRT) has proven valuable for cancer care.
Cyprine Neba Funeh +8 more
doaj +1 more source
Quantitative imaging for targeted radionuclide therapy dosimetry : technical review [PDF]
Targeted radionuclide therapy (TRT) is a promising technique for cancer therapy. However, in order to deliver the required dose to the tumor, minimize potential toxicity in normal organs, as well as monitor therapeutic effects, it is important to assess ...
Ao, Edwin CI +5 more
core +2 more sources
PEPTIDE BASED TARGETED RADIONUCLIDE THERAPIES; SCIENCE BEHIND THE SUCCESS.
The radionuclide therapies for solid and liquid malignancies are emerging field nowadays. The targeted radionuclide therapies have been in use since 1945.
Mohammed H Al Rowaily +4 more
doaj +1 more source

