Results 31 to 40 of about 3,528,989 (183)

First communication on the efficacy of combined 177Lutetium-PSMA with immunotherapy outside prostate cancer

Journal for ImmunoTherapy of Cancer, 2022
Prostate-specific membrane antigen (PSMA)-targeted radioligand therapy is a validated treatment option for patients with advanced prostate cancer. Although PSMA expression is not limited to prostate tissue, little is known about its relevance to other ...
John Prior, Solange Peters, Krisztian Homicsko, Sarah Boughdad, Niklaus Schaefer, Antonia Digklia, Clarisse Dromain, Mounir Trimech, Ana Dolcan   +8 more
doaj   +1 more source

Copper radionuclides for theranostic applications: towards standardisation of their nuclear data. A mini-review

Frontiers in Chemistry, 2023
Copper has several clinically relevant radioisotopes and versatile coordination chemistry, allowing attachment of its radionuclides to biological molecules.
Mazhar Hussain, Mazhar Hussain, Syed M. Qaim, Ingo Spahn, M. Naveed Aslam, Bernd Neumaier   +5 more
doaj   +1 more source

Immune Checkpoint Inhibitor-Mediated Cancer Theranostics with Radiolabeled Anti-Granzyme B Peptide

Pharmaceutics, 2022
Although immune checkpoint inhibitors (ICI) have revolutionized cancer management, patient response can be heterogeneous, and the development of ICI resistance is increasingly reported.
Carolina de Aguiar Ferreira, Pedram Heidari, Bahar Ataeinia, Nicoleta Sinevici, Alyssa Granito, Hritik Mahajan Kumar, Eric Wehrenberg-Klee, Umar Mahmood   +7 more
doaj   +1 more source

Continuing Nuclear Data Research for Production of Accelerator-Based Novel Radionuclides for Medical Use: A Mini-Review

Frontiers in Physics, 2021
Nuclear data are important for production and medical application of a radionuclide. This brief review concentrates on nuclear reaction cross-section data.
Syed M. Qaim, Mazhar Hussain, Ingo Spahn, Bernd Neumaier   +3 more
doaj   +1 more source

Radiological Technology for Targeted Radionuclide Therapy

Japanese Journal of Radiological Technology, 2020
Targeted radioisotope therapy (TRT) is a radiotherapy using radioisotope or drug incorporating it and has been used as a treatment for selectively irradiating cancer cells. In recent years, interest in TRT has increased due to improvements in radionuclide production technology, development of new drugs and imaging modalities, and improvements in ...
Kohei, Hanaoka, Noriaki, Miyaji, Hiroto, Yoneyama, Matsuyoshi, Ogawa, Takamasa, Maeda, Kenta, Sakaguchi, Takashi, Iimori, Hiroyuki, Tsushima   +7 more
openaire   +3 more sources

Optimizing the Safety and Efficacy of Bio-Radiopharmaceuticals for Cancer Therapy

Pharmaceutics, 2023
The precise delivery of cytotoxic radiation to cancer cells through the combination of a specific targeting vector with a radionuclide for targeted radionuclide therapy (TRT) has proven valuable for cancer care.
Cyprine Neba Funeh, Jessica Bridoux, Thomas Ertveldt, Timo W. M. De Groof, Dora Mugoli Chigoho, Parinaz Asiabi, Peter Covens, Matthias D’Huyvetter, Nick Devoogdt   +8 more
doaj   +1 more source

PEPTIDE BASED TARGETED RADIONUCLIDE THERAPIES; SCIENCE BEHIND THE SUCCESS.

Journal of Cancer and Allied Specialties, 2016
The radionuclide therapies for solid and liquid malignancies are emerging field nowadays. The targeted radionuclide therapies have been in use since 1945.
Mohammed H Al Rowaily, Daniele Dondi, Marco Chinol, Iqbal Munir, Muaadh AlAsbahi   +4 more
doaj   +1 more source

Radiopharmaceuticals: From Molecular Imaging to Targeted Radionuclide Therapy

CHIMIA, 2004
The research and development of smart radiodrugs is the goal of the Center of Radiopharmaceutical Science of ETH, PSI, and USZ. Positron Emission Tomography (PET) allows the non-invasive visualization of biochemical processes within the body ...
P. August Schubiger, Jürgen Grünberg, Simon Mensah Ametamey, Michael Honer, Elisa Garcia-Garayoa, Peter Bläuenstein, Robert Waibel, Ilse Novak-Hofer, Roger Schibli   +8 more
doaj   +1 more source

A High Separation Factor for ¹⁶⁵Er from Ho for Targeted Radionuclide Therapy

Molecules, 2021
Background: Radionuclides emitting Auger electrons (AEs) with low (0.02–50 keV) energy, short (0.0007–40 µm) range, and high (1–10 keV/µm) linear energy transfer may have an important role in the targeted radionuclide therapy of metastatic and ...
Isidro Da Silva, Taylor R. Johnson, Jason C. Mixdorf, Eduardo Aluicio-Sarduy, Todd E. Barnhart, R. Jerome Nickles, Jonathan W. Engle, Paul A. Ellison   +7 more
doaj   +1 more source

Targeted alpha-particle therapy in neuroendocrine neoplasms: A systematic review

World Journal of Nuclear Medicine, 2021
Neuroendocrine neoplasms (NENs) are a very diverse group of tumors with a worldwide rise in incidence. Systemic therapy remains the mainstay treatment for unresectable and/or metastatic NENs.
Thuan Koh, Eva Bezak, David Chan, Gabrielle Cehic   +3 more
doaj   +1 more source