Results 11 to 20 of about 3,528,989 (183)
Targeted Radionuclide Therapy of Cancer and Infections. [PDF]
Int J Mol Sci, 2023 Targeted radionuclide therapy (TRT) has been burgeoning worldwide, with several radiopharmaceuticals for the treatment of metastatic cancers being approved for clinical use [...
van der Wal BCH, Dadachova E.
europepmc +4 more sources
Prospects in folate receptor-targeted radionuclide therapy [PDF]
Frontiers in Oncology, 2013 Targeted radionuclide therapy is based on systemic application of particle-emitting radiopharmaceuticals which are directed towards a specific tumor-associated target. Accumulation of the radiopharmaceutical in targeted cancer cells results in high doses
Cristina eMüller +2 more
doaj +5 more sources
Targeted radionuclide therapy of human tumors [PDF]
International Journal of Molecular Sciences, 2015 Targeted radionuclide therapy is one of the most intensively developing directions of nuclear medicine. Unlike conventional external beam therapy, the targeted radionuclide therapy causes less collateral damage to normal tissues and allows targeted drug ...
Vodeneev, Vladimir A +7 more
core +3 more sources
Immunomodulatory effects of targeted radionuclide therapy
, 2023 International audienceIt is now clear that conventional radiation therapy can reinstate cell death immunogenicity. Recent preclinical data indicate that targeted radionuclide therapy that irradiate tumors at continuous low dose rate also can elicit ...
Deshayes, E. +5 more
core +3 more sources
EGFR-family expression and implications for targeted radionuclide therapy
, 2008 Summary High expression in the primary tumor of receptors in the EGFR-family is most often also accompanied by a similar high expression in corresponding metastases.
Carlsson, Jörgen,
core +9 more sources
Developmental trends in targeted radionuclide therapy : Biological aspects
, 2008 Targeted radionuclide therapy of hematopoietic malignancies in the clinical setting has been achieved and similar successes with solid tumors and cells disseminated from them are likely within reach.
Carlsson, Jörgen,
core +9 more sources
Introduction to radionuclide therapy
, 2008 This introductory chapter is written for those who are new to the field and desire a short overview of the present status of clinical and preclinical radionuclide therapy. In particular, this chapter provides an overview of the radiophysical concepts and
Carlsson, Jörgen,
core +9 more sources
Targeted radionuclide therapy [PDF]
Medical Physics, 2008 Targeted radionuclide therapy (TRT) seeks molecular and functional targets within patient tumor sites. A number of agents have been constructed and labeled with beta, alpha, and Auger emitters. Radionuclide carriers spanning a broad range of sizes; e.g., antibodies, liposomes, and constructs such as nanoparticles have been used in these studies. Uptake,
Lawrence E, Williams +2 more
openaire +2 more sources
Pharmaceutics, 2023 The widespread use of peptide receptor radionuclide therapy (PRRT) represents a major therapeutic breakthrough in nuclear medicine, particularly since the introduction of 177Lu-radiolabeled somatostatin analogs. These radiopharmaceuticals have especially
Léa Rubira +4 more
doaj +1 more source
Targeted radionuclide therapy frontiers in theranostics [PDF]
Frontiers in Bioscience, 2017 The concept of targeted radionuclide therapy (TRT) relies on the use of injected nuclear medicine as treating agents, targeted at the cellular or molecular level. The growth of the interest in TRT was stimulated by the advances in radionuclide production and labeling as well as by the improvement in the knowledge of appropriate and specific molecular ...
Francesca Gallivanone 1 +7 more
openaire +4 more sources