Results 21 to 30 of about 26,593 (244)
Recent Innovations and Nano-Delivery of Actinium-225: A Narrative Review
Pharmaceutics, 2023 The actinium-225 (225Ac) radioisotope exhibits highly attractive nuclear properties for application in radionuclide therapy. However, the 225Ac radionuclide presents multiple daughter nuclides in its decay chain, which can escape the targeted site ...
Sipho Mdanda +4 more
doaj +1 more source
Advances in targeted Alpha therapy for prostate cancer [PDF]
, 2019 BACKGROUND: Amongst therapeutic radiopharmaceuticals, targeted alpha therapy (TαT) can deliver potent and local radiation selectively to cancer cells as well as the tumor microenvironment and thereby control cancer while minimizing toxicity.
De Vincentis, G +11 more
core +2 more sources
What is the role of the bystander response in radionuclide therapies?
Frontiers in Oncology, 2013 Radionuclide therapy for cancer is undergoing a renaissance, with a wide range of radionuclide and clinical delivery systems currently under investigation.
Darren eBrady +2 more
doaj +1 more source
Targeted radiotherapy of neuroblastoma: future directions [PDF]
, 2017 No abstract ...
Gaze, Mark N. +4 more
core +2 more sources
Targeted Radionuclide Therapy of Human Tumors [PDF]
International Journal of Molecular Sciences, 2015 Targeted radionuclide therapy is one of the most intensively developing directions of nuclear medicine. Unlike conventional external beam therapy, the targeted radionuclide therapy causes less collateral damage to normal tissues and allows targeted drug delivery to a clinically diagnosed neoplastic malformations, as well as metastasized cells and ...
Sergey Gudkov +3 more
openaire +2 more sources
Production of Sm-153 With Very High Specific Activity for Targeted Radionuclide Therapy
Frontiers in Medicine, 2021 Samarium-153 (153Sm) is a highly interesting radionuclide within the field of targeted radionuclide therapy because of its favorable decay characteristics.
Michiel Van de Voorde +15 more
doaj +1 more source
Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics [PDF]
, 2019 Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR ...
Beattie, Bradley J. +10 more
core +2 more sources
Targeted radionuclide therapies for pancreatic cancer [PDF]
Cancer Gene Therapy, 2015 Pancreatic malignancies, the fourth leading cause of cancer deaths, have an aggressive behavior with poor prognosis, resulting in a 5-year survival rate of only 4%. It is typically a silent malignancy until patients develop metastatic disease. Targeted radionuclide therapies of cancer such as radiolabeled peptides, which bind to the receptors ...
M, Shah +5 more
openaire +2 more sources
Frontiers in Chemistry, 2023 Copper has several clinically relevant radioisotopes and versatile coordination chemistry, allowing attachment of its radionuclides to biological molecules.
Mazhar Hussain +5 more
doaj +1 more source
Peptide-targeted radionuclide therapy for melanoma [PDF]
Critical Reviews in Oncology/Hematology, 2008 Melanocortin-1 receptor (MC1-R) and melanin are two attractive melanoma-specific targets for peptide-targeted radionuclide therapy for melanoma. Radiolabeled peptides targeting MC1-R/melanin can selectively and specifically target cytotoxic radiation generated from therapeutic radionuclides to melanoma cells for cell killing, while sparing the normal ...
Yubin, Miao, Thomas P, Quinn
openaire +2 more sources