Results 21 to 30 of about 54,960 (249)

Preclinical efficacy of hK2 targeted [177Lu]hu11B6 for prostate cancer theranostics [PDF]

, 2019
Androgen ablating drugs increase life expectancy in men with metastatic prostate cancer, but resistance inevitably develops. In a majority of these recurrent tumors, the androgen axis is reactivated in the form of increased androgen receptor (AR ...
Beattie, Bradley J., Beattie, Kai A., Elgqvist, Jörgen, Eriksson, Sophie E., Larsson, Erik, Strand, Sven-Erik, Thorek, Daniel L. J., Timmermand, Oskar Vilhelmsson, Tran, Thuy A., Ulmert, David, Örbom, Anders   +10 more
core   +2 more sources

Combination Therapy, a Promising Approach to Enhance the Efficacy of Radionuclide and Targeted Radionuclide Therapy of Prostate and Breast Cancer

Pharmaceutics, 2021
In recent years, radionuclide therapy (RT) and targeted radionuclide therapy (TRT) have gained great interest in cancer treatment. This is due to promising results obtained in both preclinical and clinical studies.
Tyrillshall S. T. Damiana, Simone U. Dalm   +1 more
doaj   +1 more source

Bismuth-213 for Targeted Radionuclide Therapy: From Atom to Bedside

Pharmaceutics, 2021
In contrast to external high energy photon or proton therapy, targeted radionuclide therapy (TRNT) is a systemic cancer treatment allowing targeted irradiation of a primary tumor and all its metastases, resulting in less collateral damage to normal ...
Stephen Ahenkorah, Irwin Cassells, Christophe M. Deroose, Thomas Cardinaels, Andrew R. Burgoyne, Guy Bormans, Maarten Ooms, Frederik Cleeren   +7 more
doaj   +1 more source

Accuracy of computerized tomography in determining hepatic tumor size in patients receiving liver transplantation or resection [PDF]

, 1984
Computerized tomography (CT) of liver is used in oncologic practice for staging tumors, evaluating response to treatment, and screening patients for hepatic resection.
Bron, K, Dekker, A, Iwatsuki, S, Kowal, C, Mittal, R, Schade, R, Starzl, T, Straub, W, Van Thiel, D   +8 more
core   +1 more source

Targeted radiotherapy of neuroblastoma: future directions [PDF]

, 2017
No abstract ...
Gaze, Mark N., Mairs, Robert, Nile, Donna L., Rae, Colin, Tesson, Mathias   +4 more
core   +2 more sources

Analysis of lncRNA and mRNA Transcriptomes Expression in Thyroid Cancer Tissues Among Patients With Exposure of Medical Occupational Radiation

Dose-Response, 2019
Background: Occupational exposure of radiation among medical radiation workers contributes to the subsequent increased risk of thyroid cancer. Long noncoding RNAs (lncRNAs) are emerging as important regulators of cancer biology.
Feng Shi, Ying Liu, Min Li, Peng Wen, Qiu Qin Qian, Yibin Fan, Ruixue Huang   +6 more
doaj   +1 more source

Treatment of a mixed acinar-endocrine carcinoma with uptake on 68Gallium-DOTATOC positron emission tomography-computed tomography : a case report [PDF]

, 2017
The case of a 35-year old female patient with a diagnosis of metastatic mixed acinar-endocrine carcinoma (MAEC) is investigated in the present study.
De Both, Anneleen, De Man, Marc, Geboes, Karen, Hoorens, Anne, Troisi, Roberto, Van Vlierberghe, Hans   +5 more
core   +2 more sources

Peptide Receptor Radionuclide Therapy

The Journal of Clinical Endocrinology & Metabolism, 2022
Abstract The concept of using a targeting molecule labeled with a diagnostic radionuclide for using positron emission tomography or single photon emission computed tomography imaging with the potential to demonstrate that tumoricidal radiation can be delivered to tumoral sites by administration of the same or a similar targeting molecule
Johannes Hofland, Tessa Brabander, Frederik A Verburg, Richard A Feelders, Wouter W de Herder   +4 more
openaire   +3 more sources

Therapeutic sequences in patients with grade 1−2 neuroendocrine tumors (NET): an observational multicenter study from the ELIOS group [PDF]

, 2019
Purpose: Many different treatments are suggested by guidelines to treat grade 1−2 (G1−G2) neuroendocrine tumors (NET). However, a precise therapeutic algorithm has not yet been established.
Badalamenti, G., Bianco, A., Colao, A., De Divitiis, C., Di Maio, S., Di Sarno, A., Dolce, P., Faggiano, A., Guarnotta, V., Leo, S., Mocerino, C., Modica, R., Ottaviano, M., Palmieri, G., Puliafito, I., Riccardi, F., Tafuto, S., Tozzi, L.   +17 more
core   +1 more source

Nephrotoxicity after radionuclide therapies

Translational Oncology, 2022
Radioligand therapies have opened new treatment avenues for cancer patients. They offer precise tumor targeting with a favorable efficacy-to-toxicity profile. Specifically, the kidneys, once regarded as the critical organ for radiation toxicity, also show excellent tolerance to radiation doses as high as 50-60 Gy in selected cases.
Ashwin Singh Parihar, Sejal Chopra, Vikas Prasad   +2 more
openaire   +3 more sources