Results 61 to 70 of about 29,053 (244)

Adjuvant capecitabine in combination with docetaxel and cyclophosphamide versus anthracycline plus docetaxel and cyclophosphamide regimen in women with high‐risk, HER2‐negative breast cancer: An open‐label, randomized controlled trial

Cancer Communications, EarlyView.
Abstract Background The standard adjuvant chemotherapy for early‐stage, high‐risk breast cancer includes anthracyclines and taxanes. While anthracycline‐based regimens have proven effective in human epidermal growth factor receptor 2 (HER2)‐positive breast cancer, their efficacy may be reduced in HER2‐negative patients due to the lack of co ...
Yu Song, Yingjiao Wang, Xi Cao, Ying Xu, Yidong Zhou, Qiang Sun, Songjie Shen   +6 more
wiley   +1 more source

Approach to radionuclide therapy dosimetry planning

Nuclear Energy and Technology, 2016
Control of radiation dose absorbed in pathological volume represents one of the challenging issues in the implementation of radionuclide therapy (RNT). This paper presents new approach based on estimation of radiopharmaceutical (RP) accumulated activity ...
Yu.V. Lysak, V.M. Dyomin, V.A. Klimanov, B.Ya. Narkevich, V.L. Romodanov   +4 more
doaj   +1 more source

Frontiers of Synchrotron Methods for Actinide Science

Chemistry–Methods, EarlyView.
This article explores the application of synchrotron radiation techniques ‐ XAS, XES, HERFD, RIXS, and XRD ‐ to investigate actinide materials. It provides insights into electronic structures, oxidation states, and phase transitions, emphasizing the transformative role of these techniques in advancing nuclear materials research, environmental safety ...
Damien Prieur, Lucia Amidani, Elena F. Bazarkina, Christoph Hennig, Eleanor Lawrence Bright, Andre Rossberg, Clara L. Silva, Kristina O. Kvashnina   +7 more
wiley   +1 more source

A Novel Venom-Derived Peptide for Brachytherapy of Glioblastoma: Preclinical Studies in Mice

Molecules, 2018
We developed a bacterial expression system to produce a recombinant disintegrin, vicrostatin (VCN), whose structure is based on a natural disintegrin isolated from southern copperhead snake venom.
Steve Swenson, Radu O. Minea, Cao Duc Tuan, Thu-Zan Thein, Thomas C. Chen, Francis S. Markland   +5 more
doaj   +1 more source

Dilated cardiomyopathy evaluation with Imagenomics: combining multimodal cardiovascular imaging and genetics

ESC Heart Failure, EarlyView.
Systematic approach to dilated cardiomyopathy diagnosis. Dilated cardiomyopathy is a clinical diagnosis characterized by the presence of left ventricular dilatation and systolic disfunction unexplained by abnormal loading conditions or coronary artery disease.
Kristian Galanti, Ghaith Sharaf Dabbagh, Fabrizio Ricci, Sabina Gallina, Roberta Giansante, Ron Jacob, Edmond Obeng‐Gyimah, Leslie T. Cooper Jr, Sanjay K. Prasad, David H. Birnie, Andrew P. Landstrom, Selma F. Mohammed, Saidi Mohiddin, Mohammed Y. Khanji, Anwar A. Chahal   +14 more
wiley   +1 more source

A promising frontier of circulating messenger RNA in liquid biopsy: From mechanisms to clinical applications

International Journal of Cancer, EarlyView.
Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li, Yijin Yu, Guangyue Liu, Shunhong Zhang, Chenchen Luo, Saidi Hu, Siran Wan, Linyong Zhao   +7 more
wiley   +1 more source

The Development and Challenges of PET/MRI Dual‐Modality Imaging Probes—An Update

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT The integration of Positron emission tomography (PET) with Magnetic resonance imaging (MRI) combines the functional imaging capabilities of PET with the high‐resolution anatomical detail of MRI, creating a synergistic platform for advanced diagnostic imaging and image‐guided therapies. Central to the success of this dual‐modality system is the
Maryam Sabbaghan, Saumya Nigam, Isabella Kasabasic, Medha Manepalli, Ping Wang, Jinda Fan   +5 more
wiley   +1 more source

188Re(V) Nitrido Radiopharmaceuticals for Radionuclide Therapy

Pharmaceuticals, 2017
The favorable nuclear properties of rhenium-188 for therapeutic application are described, together with new methods for the preparation of high yield and stable 188Re radiopharmaceuticals characterized by the presence of the nitride rhenium core in ...
Alessandra Boschi, Petra Martini, Licia Uccelli   +2 more
doaj   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

Radionuclide-labelled nanoparticles for cancer combination therapy: a review

Journal of Nanobiotechnology
Radionuclide therapy (RT) is widely used to advanced local cancers. However, its therapeutic efficacy is limited to the radiation resistance of cancer cells.
Na Sun, Tao Wang, Song Zhang
doaj   +1 more source