Results 61 to 70 of about 67,679 (261)

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

open access: yesBMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang   +8 more
wiley   +1 more source

Exploring New Frontiers in Marine Radioisotope Tracing – Adapting to New Opportunities and Challenges

open access: yesFrontiers in Marine Science, 2020
Radioisotopes have been used in earth and environmental sciences for over 150 years and provide unique tools to study environmental processes in great detail from a cellular level through to an oceanic basin scale.
Tom Cresswell   +8 more
doaj   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Thermal‐induced fracture evolution and acoustic signature of Beishan granite: Insights into tensile strength of barrier system for high‐level radioactive waste disposal

open access: yesDeep Underground Science and Engineering, EarlyView.
The tensile strength of granite, a proposed host for nuclear waste, degrades severely above 400°C. We link this to specific microcracking patterns captured by acoustic emission, establishing a scientific basis for assessing repository safety under thermal load.
Wei Zeng   +7 more
wiley   +1 more source

137Cs content in European blueberry (Vaccinium Myrtillus L.) in forests of Ukrainian Polissia in different periods after the accident at ChNPP [PDF]

open access: yesЯдерна фізика та енергетика, 2018
It has been established that intensive penetration of 137Cs both into the above-ground part of phytomass and blueberry is continuing at present. The transition coefficients of 137Cs (m2kg-110-3) in the above-ground part of European blueberry (17 - 53 ...
V. P. Krasnov   +6 more
doaj  

Global Real‐World Outcomes of Olaparib in Metastatic Castration‐Resistant Prostate Cancer Patients With Homologous Recombination Repair Alterations

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Evidence to guide the treatment for patients with metastatic castration‐resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with tumor harboring HRR alterations, progressed on a prior androgen ...
Lorena Incorvaia   +35 more
wiley   +1 more source

Separation method for Pu, Am and Sr in large air filter sample sets

open access: yesMethodsX, 2020
A sequential separation method for Pu, Am, and Sr was applied for unusually large sample sets of air filters. The sample sets were combined weekly air filters covering sampling time from three months to five years, while in original method, the analyzed ...
Susanna Salminen-Paatero, Jussi Paatero
doaj   +1 more source

Optimising hypoxia PET imaging and its applications in guiding targeted radiation therapy for non‐small cell lung cancer: a scoping review

open access: yesJournal of Medical Radiation Sciences, Volume 72, Issue 1, Page 106-118, March 2025.
This review article reports that quantification of hypoxic volumes using PET in the pre‐radiation therapy setting is of prognostic value and indicative of treatment response in non‐small cell lung cancer. Abstract Introduction Non‐small cell lung cancer (NSCLC) is the leading cause of cancer‐related death. Definitive treatment includes chemotherapy and
Carol Marks, Michelle Leech
wiley   +1 more source

PECULIARITIES OF RADIOACTIVE CONTAMINATION OF THE FOREST ECOSYSTEM AFTER THE CHERNOBYL ACCIDENT

open access: yesРадиационная гигиена, 2017
Chernobyl accident has influenced greatly all spheres of life of the affected territories, changing the life-style of the local population. [1, 2]. Investigation of the radionuclides behavior in natural conditions becomes more and more important which is
K. V. Varfolomeeva
doaj  

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