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Adverse reactions to radiopharmaceuticals: liver radiopharmaceuticals
Nuclear Medicine Communications, 2021Radiopharmaceuticals are radioactive compounds used in nuclear medicine, consisting of a radioactive moiety and a pharmaceutical part. Radiopharmaceuticals are used for diagnosis (predominantly) and therapy (to a lesser extent). Adverse drug reactions are undesirable, unexpected, often harmful drug responses that occur when the drug is administered in ...
Humeyra, Battal, Asuman Yekta, Ozer
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Pitfalls With Radiopharmaceuticals
The American Journal of the Medical Sciences, 2011There is a considerable body of evidence describing that the pharmacokinetics and pharmacodynamics of radiopharmaceuticals may be changed by a variety of drugs, disease states and in some cases, surgical procedures.: To systematically search the medical literature and review the published evidence on adverse reactions to radiopharmaceuticals.MEDLINE ...
Ralph, Santos-Oliveira, Márcio, Machado
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International Journal of Radiation Oncology*Biology*Physics, 2006
The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
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The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
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2023
Radiopharmaceuticals (RPs) have revolutionized the fields of nuclear medicine, diagnostic imaging, and targeted therapy. The chapter begins by elucidating the brief explanation of production and design of RPs. This chapter focuses on newly produced diagnostic & therapeutic radiopharmaceuticals that are being employed in normal clinical settings as ...
Vipasha Sharma +4 more
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Radiopharmaceuticals (RPs) have revolutionized the fields of nuclear medicine, diagnostic imaging, and targeted therapy. The chapter begins by elucidating the brief explanation of production and design of RPs. This chapter focuses on newly produced diagnostic & therapeutic radiopharmaceuticals that are being employed in normal clinical settings as ...
Vipasha Sharma +4 more
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Bispidines for radiopharmaceuticals
Dalton Transactions, 2018Radiometal based radiopharmaceuticals for imaging and therapy require selective ligands (bifunctional chelators, BFCs) that form metal complexes, which are inert against trans -chelation under physiological conditions, linked to a biological vector, directing them to the targeted tissue ...
Peter Comba +3 more
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The Regulation of Radiopharmaceuticals
JAMA: The Journal of the American Medical Association, 1985To the Editor.— The recent editorial on the Food and Drug Administration's (FDA) role in the drug approval process is appropriate. 1 In our opinion, the FDA has shown concern about infringement upon the practice of medicine. 2 Such may not be said for the Nuclear Regulatory Commission (NRC), in its interpretation of its statutory authority to regulate
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SPECT Radiopharmaceuticals for Dementia
Current Radiopharmaceuticals, 2014Over the last decade the interest towards functional neuroimaging has gradually increased, especially in the field of neurodegenerative diseases. At present, diagnosis of dementia is mostly clinical. Numerous modalities of neuroimaging are today available, each of them allowing a different aspect of neurodegeneration to be investigated. Although during
Guidotti, Claudio +6 more
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