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MEDICINAL RADIOPHARMACEUTICAL CHEMISTRY OF METAL RADIOPHARMACEUTICALS
COSMOS, 2012Metal complexes have been used as medicinal compounds. Metals have advantageous features over organic compounds. Significant applications of metal complexes are in the field of nuclear medicine. Radiopharmaceuticals are drugs containing radioisotopes used for diagnostic and therapeutic purposes.The generalized targeting strategy for molecular imaging ...
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Quality Control of Radiopharmaceuticals [PDF]
, 1979 Since radiopharmaceuticals are intended for human administration, it is imperative that they undergo strict quality control measures. Basically, quality control involves several specific tests and measurements that ensure the purity, potency, product identity, biologic safety, and efficacy of radiopharmaceuticals.
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International Journal of Radiation Oncology*Biology*Physics, 2006
The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
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The term "naked" radiopharmaceuticals, more appropriately, "unbound" radiopharmaceuticals, refers to any radioisotope used for clinical research or clinical purposes that is not attached to a chemical or biological carrier, and that localizes in various tissues because of a physiologic or chemical propensity/affinity, or secondary to focal anatomic ...
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A New Radiopharmaceutical for Placentography
Radiology, 1964Radioisotopic placentography requires accurate localization of the maternal component of placental circulation by detection of a circulating radionuclide confined to the maternal intravascular space. Sodium-24 chloride was the tracer first employed in placentography (2) but its rapid extravascular diffusion was disadvantageous.
Elmer E. Stickley +2 more
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Drug interactions with radiopharmaceuticals
European Journal of Nuclear Medicine, 1994Considerable information on documented drug and radiopharmaceutical interactions has been assembled in a tabular form, classified by the type of nuclear medicine study. The aim is to provide a rapid reference for nuclear medicine staff to look for such interactions.
Stuart Hesslewood, Emmeline Leung
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2019
Copper (Cu) is a transition metal with atomic number 29, involved in several physiological processes, being cofactor for numerous enzymes, such as the “Cu/Zn superoxide dismutase,” “cytochrome-C-oxidase,” “tyrosinase,” “ceruloplasmin,” and other proteins.
Antonio Bagnato +6 more
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Copper (Cu) is a transition metal with atomic number 29, involved in several physiological processes, being cofactor for numerous enzymes, such as the “Cu/Zn superoxide dismutase,” “cytochrome-C-oxidase,” “tyrosinase,” “ceruloplasmin,” and other proteins.
Antonio Bagnato +6 more
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Radiochemistry and radiopharmaceuticals
Annual Reports Section "A" (Inorganic Chemistry), 2006Following last year’s precedent this section of Annual Reports will review not only recent progress in radiochemistry, including isotope production and environmental aspects, but also in the production of radiopharmaceuticals and their use in nuclear medicine for imaging.
David S. Urch, Michael J. Welch
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Anti-cancer radiopharmaceuticals
Anti-Cancer Drugs, 1991Therapeutic nuclear medicine is rapidly developing as an additional treatment modality in oncology. A great variety of specific tumor-seeking radiopharmaceuticals is applied both for diagnostic scintigraphy and treatment, using multiple routes and mechanisms to target radionuclides at tumors.
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Characteristics of Specific Radiopharmaceuticals
1979In Chapter 6 the general principles of labeling methods were discussed, particularly iodination and 99mTc-labeling, and kit preparation of 99mTc-radiopharmaceuticals was described. In this chapter the basic principles of preparation, labeling yield, stability, storage conditions, and other characteristics of several radiolabeled compounds most commonly
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