Results 141 to 150 of about 34,696 (251)

A Modular, Accessible, and Low‐Cost Photoreactor with Precision Light and Temperature Control for Small‐Scale Reactions

open access: yesChemistry–Methods, Volume 6, Issue 6, June 2026.
This modular, low‐cost, light‐emitting diode (LED)‐based photoreactor facilitates modulation of light intensity, choice of wavelength, and thermal equilibration for photochemical reactions at a small scale with the potential to normalize research outputs across different laboratories.
Irma G. Vermeijlen   +5 more
wiley   +1 more source

Lifespan Trajectories of Asymmetry in White Matter Tracts

open access: yesHuman Brain Mapping, Volume 47, Issue 8, June 1, 2026.
(A) Large‐scale lifespan modeling of white matter asymmetry. Diffusion MRI data from 35,000+ individuals (0‐100 years) across 50 cohorts were used to generate normative lifespan trajectories of white matter asymmetry. Thirty bilateral tracts were segmented, and microstructural (FA, MD, AD, RD) and macrostructural (volume, length) features were ...
Sam Bogdanov   +72 more
wiley   +1 more source

Synthesis and Evaluation of 99mTc Essential Analogue of DUPA PSMA Inhibitor for Its Potential Use in Prostate Cancer Imaging

open access: yesChemistrySelect, Volume 11, Issue 21, 4 June 2026.
ABSTRACT DUPA (2‐[3‐(1,3‐dicarboxy propyl) ureido] pentanedioic acid) is a known small molecule prostate‐specific membrane antigen (PSMA) enzyme inhibitor that targets the PSMA receptor found overexpressed on prostate cancer. The present work synthesizes and evaluates a 99mTc (technetium) “metal essential” glutamate complex, which mimics the DUPA ...
Navin Sakhare   +11 more
wiley   +1 more source

Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions

open access: yesSmall Methods, Volume 10, Issue 12, 23 June 2026.
This review outlines the rational design, synthesis, and standardized characterization of organic afterglow nanoparticles for biomedical imaging and therapy. Mechanistic insights into chemically initiated electron exchange luminescence and reactive oxygen species‐mediated processes are connected to molecular engineering and nanoparticle fabrication ...
Asma Harun   +6 more
wiley   +1 more source

Checkpoint inhibitors, obinutuzumab plus PET‐adapted ultra‐low dose nodal radiotherapy yield high efficacy in treatment‐naïve follicular lymphoma: Results from the phase II ‘FLUORO’ study

open access: yesBritish Journal of Haematology, Volume 208, Issue 6, Page 2026-2035, June 2026.
Summary Follicular lymphoma (FL) first‐line chemoimmunotherapy yields high efficacy but serious toxicity in 65% of patients. In high tumour burden treatment‐naïve FL, we aimed to exploit known immunostimulatory and cytotoxic properties of combination checkpoint inhibition (atezolizumab) and obinutuzumab (6 cycles) with positron emission tomography (PET)
Arina Martynchyk   +15 more
wiley   +1 more source

RADIOPHARMACEUTICALS PACKAGE MONITORING SYSTEM

open access: yes, 2011
Os radiofármacos são usados no campo da medicina nuclear como marcadores no diagnóstico e no tratamentode muitas doenças. A produção de um radiofármaco envolve dois processos principais: a produção do radionuclídeo em que farmacêutica baseia-se, e a ...
AGHINA, Mauricio Alves da Cunha e   +4 more
core  

25 Years of "Loop" Radiochemistry for PET Imaging. [PDF]

open access: yesJ Labelled Comp Radiopharm
Murrell E, Khan S, Vasdev N.
europepmc   +1 more source

Human Absorption, Metabolism, and Excretion (hAME) Mass Balance Studies in Patients With Cancer

open access: yesClinical and Translational Science, Volume 19, Issue 6, June 2026.
ABSTRACT Radiolabeled mass balance human studies are a critical component of clinical pharmacology programs supporting the development of new investigational drugs. These studies provide information about absorption, metabolism, and excretion (AME) of the parent drug and metabolite(s) in the human body and are normally conducted in healthy volunteers ...
Begoña de las Heras   +9 more
wiley   +1 more source

Neuroendocrine tumours through an epigenetic lens: Emerging insights for diagnosis and treatment

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Neuroendocrine tumours (NETs) are well‐differentiated epithelial neuroendocrine neoplasms that frequently develop in the small intestine, pancreas, and lungs. NETs originate from neuroendocrine cells specialized in hormone secretion implicated in a number of physiological processes.
Victoria Jacquot   +4 more
wiley   +1 more source

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