Results 121 to 130 of about 34,871 (236)
Diffusion MRI and α‐Synuclein Seed Amplification Status in Parkinson's Disease
Annals of Neurology, Volume 100, Issue 2, Page 295-304, August 2026.Objective Positive α‐synuclein seed amplification assay (SAA) is a biomarker found in most people with Parkinson's disease (PD). We explored if free‐water (FW) imaging detects microstructural differences in the brains of patients with early PD with SAA+ or SAA– status.
Shannon Y. Chiu +145 more
wiley +1 more source
Applications of Artificial Intelligence in Cancer Diagnosis and Treatment
Cancer Medicine, Volume 15, Issue 8, August 2026.This review explores how AI and multimodal data fusion transform oncology through enhanced screening, precision diagnosis, and personalized therapy. By dissecting core challenges—including data bias and explainability—it provides a strategic framework for the digital transformation and ethical implementation of AI in clinical cancer care.
Yifeng Xie +6 more
wiley +1 more source
Glia, Volume 74, Issue 8, August 2026.Using [18F]‐SMBT‐1 PET, we longitudinally tracked MAO‐B–expressing reactive astrocytes during orofacial neuropathic pain development in rats, revealing region‐ and time‐specific astrocyte activation during pain chronification. ABSTRACT Chronic neuropathic pain represents a significant global health burden and is hypothesized to be maintained by an ...
Lewis S. Crawford +14 more
wiley +1 more source
Medical Physics, Volume 53, Issue 8, August 2026.Abstract Background Autoradiography provides microscale mapping of radionuclide distributions, offering a promising approach to complement nuclear medicine imaging for small‐scale radiopharmaceutical therapy (RPT) research. However, while quantitative protocols for α‐emitters are well‐established, comparable methods for β‐emitters, such as the widely ...
Ohyun Kwon +12 more
wiley +1 more source
High pressure liquid chromatographic assay of technetium in solutions of sodium pertechnetate produced at the AAEC Research Establishment. [PDF]
, 1985 High pressure liquid chromatography (HPLC) is used for the assay of nanogram quantities of technetium and to determine technetium in decayed pharmaceutical products derived from three methods of manufacture.
Farrington, KJ
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CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 8, August 2026.ABSTRACT The accelerated development of innovative anticancer therapies has led to the early approval of an increasing number of drugs. However, clinical evidence available at the time of approval is often limited, necessitating additional post‐marketing studies to supplement safety and efficacy data.
Aina Tsuno, Hiroe Kitagaki, Hideki Maeda
wiley +1 more source
Brain Serotonin Transporter Is Elevated in Obesity: Bayesian and Frequentist Meta‐Analyses
Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 6919-6926, August 2026.ABSTRACT Aims The brain plays a critical role in controlling energy balance. Previous studies have mainly focused on dopaminergic mechanisms, whereas much less attention has been paid to serotonin during the emergence of overweight and obesity. Therefore, this study investigated the association between serotonin transporter (SERT) availability and ...
Kyoungjune Pak
wiley +1 more source
International Journal of Urology, Volume 33, Issue 8, August 2026.ABSTRACT Background Radium‐223 dichloride (Ra‐223) is an effective treatment for metastatic castration‐resistant prostate cancer (mCRPC) with bone metastases. However, predictive factors associated with treatment efficacy remain unclear. This study evaluated prognostic factors associated with the efficacy of Ra‐223 and investigated outcomes according ...
Kodai Abe +14 more
wiley +1 more source
RADIOPHARMACEUTICALS PACKAGE MONITORING SYSTEM [PDF]
, 2011 Os radiofármacos são usados no campo da medicina nuclear como marcadores no diagnóstico e no tratamentode muitas doenças. A produção de um radiofármaco envolve dois processos principais: a produção do radionuclídeo em que farmacêutica baseia-se, e a ...
AGHINA, Mauricio Alves da Cunha e +4 more
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