Results 111 to 120 of about 48,541 (237)

Strategies for Innovative Development of Tumor-targeted Theranostic Radiopharmaceuticals

Yuanzineng kexue jishu
Radiopharmaceutical is an essential component of nuclear medicine and have demonstrated significant potential in disease diagnosis and treatment. In recent years, several tumor-targeted theranostic radiopharmaceuticals have been approved for market ...
HUANG Xuhu1, 2, 3, CHEN Huan1, 2, 3, LI Kexin1, 2, 3, WANG Ning1, 2, 3, ZHUANG Jin1, 2, 3, LI Hongyu1, 2, 3, DU Jin2, 3, 4
doaj   +1 more source

Comparison of Morbidity Between Sentinel Lymph Node Biopsy and Elective Neck Dissection in Dogs With Head and Neck Malignancies

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Elective neck dissection (END) and sentinel lymph node biopsy (SLNB) are suggested for nodal staging of canine head and neck malignancies (HNM). This study aims to compare the morbidity of END to SLNB. Seventy‐six client‐owned dogs with HNM that underwent END (n = 28) or SLNB (n = 48) in two institutions were retrospectively enrolled ...
Lavinia Elena Chiti, Dominique Leu, Roberta Ferrari, Ester Luconi, Patrizia Boracchi, Elisa Maria Gariboldi, Damiano Stefanello, Mirja Christine Nolff   +7 more
wiley   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, Volume 73, Issue 5, May 2026.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Staging lung cancer: total-body PET/CT or whole-body PET/CT?

EJNMMI Research
Background Total Body PET/CT is increasingly used in clinical practice, but its benefits for lung cancer staging are not fully established. This study aimed to evaluate the impact of Total Body PET/CT on lung cancer staging compared to traditional Whole ...
Xiaoxiang Zhang, Jiahao Xie, Yuzhao Zheng, Ying Tian, Xiaohui Chen, Li Chen, Kemin Zhou, Penghui Sun, Wenlan Zhou, Hubing Wu   +9 more
doaj   +1 more source

Integrating polygenic and transcriptional risk scores for detecting Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Early detection of Alzheimer's disease (AD) is essential, yet existing biomarkers are invasive or costly. Polygenic risk scores (PRS) and transcriptional risk scores (TRS) may offer accessible alternatives, but their combined predictive performance remains understudied.
Jiyun Hwang, Jung‐Min Pyun, Joo‐Yeon Lee, Jeong Su Park, Paula J. Bice, Andrew J. Saykin, Joohon Sung, SangYun Kim, Young Ho Park, Kwangsik Nho, for the Alzheimer's Disease Neuroimaging Initiative   +10 more
wiley   +1 more source

Radiopharmaceuticals for myocardial perfusion imaging: SPECT & PET [PDF]

, 2015
Myocardial perfusion imaging (MPI) is used on a daily basis to access coronary blood flow in patients that are suspected or have known Coronary Artery Disease (CAD). A Single Photon Emission Computed Tomography (SPECT) or and Positron Emission Tomography
Adães, Rui, Fernandes, Marco, Pereira, Edgar, Sousa, Eva   +3 more
core  

Usage and positivity rates of Alzheimer's disease biomarkers in a memory clinic

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Usage of biomarker tests for Alzheimer's disease pathology and rates of positivity were assessed at the Washington University Memory Diagnostic Center. METHODS Patients who underwent at least one biomarker test for clinical purposes between June 2021 and March 2025 were included (n = 1136). Data were retrospectively extracted from
Anna Hofmann, Benjamin Saef, William J. B. Powell, Madeline Paczynski, Maria R. Ponisio, Clara Vila‐Castelar, Zachary Posey, Inez Y. Oh, Mackenzie R. Hofford, Melissa Aldinger, Randall J. Bateman, Cyrus A. Raji, Tammie L. S. Benzinger, Carlos Cruchaga, Alan Dow, Rachel Buckley, Chengjie Xiong, John C. Morris, B. Joy Snider, Aditi Gupta, Suzanne E. Schindler   +20 more
wiley   +1 more source

Optimization of Reaction Conditions in the Production of Gadolinium Diethylenetriamine Pentaacetate-Folate [PDF]

, 2015
A previous study has performed the laboratory-scale synthesis and characterization of Gadolinium Diethylenetriaminepentaacetate-Folate. Some parameters associated with the synthesis have been defined.
Anggraeni, A., Fauzia, R. P., Gunawan, A. H., Mutalib, A.   +3 more
core  

When Does Alzheimer's Disease Start? Plasma Aβ42/40 Assays Show Steep Changes at Aβ‐PET Centiloid 15, Mean Age of 66 Years

Annals of Neurology, Volume 99, Issue 5, Page 1327-1342, May 2026.
Objective Sporadic late‐onset Alzheimer's disease (AD) is characterized by a long pre‐clinical phase where amyloid‐beta (Aβ) and tau begin to accumulate in the brain. The primary objective was to determine the age at which AD starts by finding the average population age when both positron emission tomography (PET) Aβ (Aβ‐PET) and plasma Aβ42/40 become ...
Rodrigo Cánovas, Timothy Cox, Vincent Doré, Pierrick Bourgeat, Jurgen Fripp, Azadeh Feizpour, Rosita Shishegar, Christopher J. Fowler, Simon M. Laws, Tenielle Porter, Stephanie Rainey‐Smith, Leslie M. Shaw, Randall J. Bateman, Yan Li, Ovod Vitaliy, Michael W. Weiner, John C. Morris, Tammie L.S. Benzinger, Suzanne E. Schindler, Akinori Nakamura, Takeshi Iwatsubo, Takeshi Ikeuchi, Takashi Kato, Paul Maruff, Hamid R. Sohrabi, Christopher C. Rowe, Ralph N. Martins, Colin L. Masters, James D. Doecke, for the Alzheimer's Disease Neuroimaging Initiative   +29 more
wiley   +1 more source

Positron Emission Tomography Imaging of Bacterial Infections With an Enterobactin Analog to Monitor Treatment Efficacy With a Catechol Antibiotic

Angewandte Chemie, Volume 138, Issue 17, 20 April 2026.
Synopsis. The [68Ga]GaIII‐TREN‐CAM radiochelate selectively accumulates in Gram‐negative sites of infection and noninvasively monitors treatment response a siderophore antibiotic. ABSTRACT Positron emission tomography (PET) is an emerging tool under clinical investigation for the detection of bacterial infections.
M. Andrey Joaqui‐Joaqui, Phuong Nguyen Tran, Axia Marlin, Fiona Armstrong‐Pavlik, Minhua Cao, Valérie C. Pierre, Eszter Boros   +6 more
wiley   +2 more sources