Results 101 to 110 of about 34,696 (251)
Movement Disorders, EarlyView.Abstract Background Serum neurofilament light chain (NfL) levels, a marker of axonal damage, are generally elevated in neurodegenerative conditions, but results in idiopathic Parkinson's disease (iPD) have been inconsistent. The p.A53T SNCA mutation usually leads to a severe form of PD.
Nikolaos Papagiannakis +213 more
wiley +1 more source
, 2013 Tato bakalářská práce si klade za úkol zpracovat dostupné informace o používaných radiofarmacích. Zaměřuje se na jejich výrobu a použití. Radiofarmaka patří do oboru nukleární medicíny, která hraje velmi významnou roli při diagnostice onemocnění a ...
Nedomová, Eva
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Pitfalls and limitations of SPECT, PET, and therapeutic radiopharmaceuticals
, 2015 Radiopharmaceuticals are widely accepted to be a very safe class of drugs, with very few adverse reactions and unexpected biodistributions. However, problems can arise because of technical issues in manufacture or reconstitution, patient preparation, or ...
Ballinger, James R.
core +1 more source
Movement Disorders, EarlyView.Abstract Background Differentiating progressive supranuclear palsy (PSP) from Parkinson's disease (PD) can be clinically challenging. In the neuroimaging field, radiomics has emerged as a promising approach to capture subtle microstructural and textural image alterations, improving differential diagnoses.
Chiara Camastra +8 more
wiley +1 more source
Hydrazine Derivatives as a Platform for Site-Specific Labelling of Peptides for in vivo Molecular Imaging of Disease [PDF]
The 6-hydrazinonicotinyl group, known as HYNIC, is an attractive bifunctional coupling agent for preparing 99mTc-labeled peptides and proteins for medical imaging.
Holland, Charlotte
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Adverse Events of Diagnostic Radiopharmaceuticals: A Systematic Review [PDF]
, 2019 Diagnostic radiopharmaceuticals used in nuclear medicine can cause adverse events. Information on these adverse events is available in case reports and databases but may not be readily accessible to healthcare professionals.
Jager, Pieter L. +7 more
core +1 more source
Long‐Duration Response to Levodopa in the PPMI‐Cohort
Movement Disorders, EarlyView.Abstract Background Treatment of Parkinson's disease (PD) with levodopa results in a sustained reduction of symptoms. Although the plasma half‐life of levodopa is short, it elicits a lasting effect, the long‐duration levodopa response (LDR). A decrease in LDR as PD progresses has been linked to motor complications, but long‐term data on the LDR and its
Nils Schnalke +3 more
wiley +1 more source
2D van der Waals System Integrated with Targeting Radio‐Diagnostic and Imaging Functions
Small, EarlyView.Layered double hydroxide (LDH) nanoplates were engineered for tumor‐targeted imaging and therapy. By exploiting folate receptor (FR) expression levels, the system achieves selective tumor accumulation and high‐resolution dual PET/fluorescence (PET/FL) imaging.
Sairan Eom +6 more
wiley +1 more source
Assessment of cell damage produced by 161Tb-/177Lu-somatostatin analog radiopharmaceuticals
, 2023 The use of 161Tb has been proposed for targeted radionuclide therapy (TRT) because its decay properties are quite similar to those of 177Lu, which is currently the most used radionuclide in TRT.
Guillermina Ferro-Flores +5 more
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Journal of Medical Imaging and Radiation Oncology, EarlyView.ABSTRACT Introduction Accurate preoperative physiological assessment is critical for high‐risk patients undergoing lung resection to predict postoperative lung function. This study compared quantitative dual‐energy CT (DECT) perfusion with SPECT/CT for lobar perfusion mapping in an at‐risk oncological cohort.
Jack Edward Liu +6 more
wiley +1 more source