Results 81 to 90 of about 48,541 (237)

Computer Vision Analysis for Objective Motor Assessment in Parkinson's Disease: A Retrospective Study

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background The Movement Disorder Society‐Unified Parkinson's Disease Rating Scale‐Part III (MDS‐UPDRS‐III) is subjective and insensitive to subtle changes in patients with Parkinson's disease (PD). Computer vision (CV) can extract objective kinematics from routine outpatient videos, potentially augmenting the accuracy of the motor assessment ...
Pasquale Maria Pecoraro   +12 more
wiley   +1 more source

SINTESIS DAN KARAKTERISASI NUKLEOTIDA BERTANDA [α-32P]ATP

open access: yesJurnal Riset Kimia, 2019
The utilization of nuclear technology in health sector with molecular techniques is increasingly developed today, especially in Indonesia.  One of which is nucleotide compound marked with [α-32P]ATP, this compound has been used as tracer for ...
Wira Yusril Rahman   +6 more
doaj   +1 more source

Alzheimer's Biomarkers and Visuospatial Cognition in Parkinson's Disease: Modification by α‐Synuclein and Mediation of Age Effects

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Visuospatial deficits in Parkinson's disease (PD) often precede dementia and complicate daily functioning. Alzheimer's disease (AD) pathology and α‐synuclein aggregation frequently co‐occur in PD, but their combined impact on cognition is unclear.
David Ledingham   +8 more
wiley   +1 more source

Effect of Time-of-Flight and Regularized Reconstructions on Quantitative Measurements and Qualitative Assessments in Newly Diagnosed Prostate Cancer With 18F-Fluorocholine Dual Time Point PET/MRI. [PDF]

open access: yes, 2017
Recent technical advances in positron emission tomography/magnetic resonance imaging (PET/MRI) technology allow much improved time-of-flight (TOF) and regularized iterative PET reconstruction regularized iterative reconstruction (RIR) algorithms.
Behr, Spencer C   +5 more
core   +1 more source

Are radiopharmaceuticals safe? the case of FDG-18 [PDF]

open access: yes, 2012
5 p.Too many false-positive and adverse reactions related to radiopharmaceuticals take place every day in hospitals routine, but many are not reported or even sensed.
FLEMING, Brandon, SANTOS-OLIVEIRA, Ralph
core   +1 more source

Clinical Progression in Alpha‐Synuclein Positive LRRK2‐PD and Sporadic Parkinson's Disease: A Longitudinal Analysis

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background LRRK2‐Parkinson's disease (LRRK2‐PD) is biologically heterogeneous with approximately 30% lacking aggregated alpha synuclein (αSyn) in cerebrospinal fluid by seed amplification assay (SAA). Prior work has suggested slower progression in LRRK2‐PD compared to sporadic PD (sPD).
Lucy A. Morse   +224 more
wiley   +1 more source

Recent Advances and Strategies in the Development of Therapeutic Radiopharmaceuticals

open access: yesJournal of Isotopes
Therapeutic radiopharmaceuticals can be employed in the treatment of various tumor diseases,and their global market share is likely to witness an explosive growth in the recent decade.
Mianxue LIU   +8 more
doaj   +1 more source

Discordance of Dopaminergic Dysfunction and Subcortical Atrophy by α‐Synuclein Status in Sporadic and Genetic Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is characterized by predominantly neuronal α‐synuclein pathology and dopaminergic dysfunction. Cerebrospinal fluid (CSF) seeding amplification assays (SAA) detect α‐synuclein aggregates in vivo, but not all patients with PD have a positive SAA.
Michael Tran Duong   +186 more
wiley   +1 more source

Non-clinical Studies of Radiopharmaceuticals: Analysis of National and International Regulatory Practice (Review)

open access: yesРегуляторные исследования и экспертиза лекарственных средств
INTRODUCTION. Currently in the Russian Federation and the Eurasian Economic Union (EAEU), the conduct of non-clinical studies of radiopharmaceuticals is regulated by general guidelines on non-clinical studies, which are applicable to multiple groups of ...
O. E. Klementyeva   +5 more
doaj   +1 more source

The Study of {99}mTc-Aluminum Oxide Using for Sentinel Lymph Nodes Detection in Experiment [PDF]

open access: yes, 2016
We have established a multiple higher accumulation of {99}mTc-Al[2]O[3] in SLM in comparison with import analogue. Considering this fact the clinical use of new domestic radiopharmaceutical will facilitate intraoperative identification of such ...
Bragina, Olga Dmitrievna   +8 more
core   +1 more source

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