Results 171 to 180 of about 29,971 (224)

Radioprotection by metals: Selenium

Advances in Space Research, 1992
The need exists for compounds that will protect individuals from high-dose acute radiation exposure in space and the agents that might be less protective but less toxic and longer acting. Metals and metal derivatives provide a small degree of radioprotection (dose reduction factor < or = 1.2 for animal survival after whole-body irradiation). Emphasis
J F, Weiss, V, Srinivasan, K S, Kumar, M R, Landauer   +3 more
openaire   +2 more sources

Radioprotection of DNA by Polyamines

International Journal of Radiation Biology, 1995
Putrescine, spermidine and spermine are natural polyamines bearing at neutral pH the net electrical charges +2, +3 and +4 respectively. We report here the radioprotective effect of these polyamines on the radiolysis of pBR322 plasmid DNA. We observe a very efficient protection against fast neutron-induced single and double-strand breakage in the ...
M, Spotheim-Maurizot, S, Ruiz, R, Sabattier, M, Charlier   +3 more
openaire   +2 more sources

Radioprotective Action of Methoxamine

Nature, 1959
SEVERAL vasoconstrictor compounds have been shown to protect animals against lethal doses of X-radiation. A review of this field has recently been prepared by Pihl and Eldjarn1. Methoxamine, β-hydroxy, β-(2,5-dimethoxyphenyl)-iso-propylamine, is a compound with pronounced vasoconstrictor properties2 which does not appear to have been previously tested ...
A D, SMITH, M J, ASHWOOD-SMITH, D, LOWMAN   +2 more
openaire   +2 more sources

Antioxidant Effects in Radioprotection

1990
Reactive Oxygen Intermediates and Oxygen Metabolism. Reactive Oxygen intermediates such as O 2 - , H2O2 and OH might not be generated only during the initial radiolytic phase of radia tion injury, but also in a later metabolic phase, involving oxygen.
P, Bienvenu, F, Herodin, M, Fatome, J F, Kergonou   +3 more
openaire   +2 more sources

Radioprotection and recovery by dithiothreitol

Experientia, 1970
Le DTT reduit et oxyde, administre a des sourris irradiees par des doses mortelles de rayons X, provoque une survie notable; le meilleur effect est obtenu avec le DTT oxyde, administre indifferemment avant ou apres l'irradiation.
C, Falconi, P, Scotto, P, De Franciscis
openaire   +2 more sources

Radioprotective reverse orchidopexy

Journal of Pediatric Surgery, 2002
With the improvement in long-term outcome from childhood malignancy, the expected quality of life is important. This study was to assess the value of reverse orchidopexy in patients requiring radiotherapy to the groin or pelvic area.The details of 6 boys (age 2 to 13 years) who had malignancy necessitating groin or pelvic radiotherapy were reviewed ...
B O, Okoye, D, Spooner, J F, Townley, P, Gornall   +3 more
openaire   +2 more sources

Radioprotective Gene Therapy

Current Gene Therapy, 2003
Control of cancer by irradiation therapy alone or in conjunction with combination chemotherapy is often limited by organ specific toxicity. Ionizing irradiation toxicity is initiated by damage to normal tissue near the tumor target and within the transit volume of radiotherapy beams. Irradiation-induced cellular, tissue, and organ damage is mediated by
J S, Greenberger, M W, Epperly, J, Gretton, M, Jefferson, S, Nie, M, Bernarding, V, Kagan, H L, Guo   +7 more
openaire   +2 more sources

Radioprotective gene therapy

Expert Opinion on Biological Therapy, 2011
Radiation-induced myelosuppression or mucositis can limit the effectiveness of radiotherapy by requiring dose reduction or delaying treatment of tumour patients. The transfer of a radioprotective gene into normal tissue cells would provide the opportunity to reduce the risks associated with haematopoietic or intestinal toxicity after irradiation ...
Patrick, Maier, Marlon R, Veldwijk, Frederik, Wenz   +2 more
openaire   +2 more sources

Radioprotective Potency of Nanoceria

Current Radiopharmaceuticals
Abstract: Cancer presents a significant medical challenge that requires effective management. Current cancer treatment options, such as chemotherapy, targeted therapy, radiotherapy, and immunotherapy, have limitations in terms of their efficacy and the potential harm they can cause to normal tissues.
Maryam, Alvandi, Zahra, Shaghaghi, Soghra, Farzipour, Zeynab, Marzhoseyni   +3 more
openaire   +2 more sources

The radioprotective effect of solcoseryl

Experientia, 1974
Solcoseryl® ruft bei Mausen 1 h vor Bestrahlung mit letalen Dosen von γ-Strahlen, i.p. oder p.o. appliziert, ein fast durchwegs 100%iges Uberleben im Zeitraum von 30 Tagen hervor.
D, Bauer, A, Locker
openaire   +2 more sources