Results 121 to 130 of about 27,469 (292)

RTA‐408 Enhances Radiosensitivity and Inhibited Tumor Progression via JNK Pathway in Glioblastoma

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Glioblastoma (GBM) is an aggressive brain tumor with poor prognosis owing to its high invasiveness and resistance to therapy. RTA‐408, a synthetic triterpenoid and nuclear factor erythroid 2‐related factor 2 activator, exhibits anti‐inflammatory and anti‐cancer properties; however, its effects on GBM remain unclear. This study investigated the
Hung‐Pei Tsai   +6 more
wiley   +1 more source

Talazoparib Is a Potent Radiosensitizer in Small Cell Lung Cancer Cell Lines and Xenografts

open access: yesClinical Cancer Research, 2018
Purpose: Small cell lung cancer (SCLC) is an aggressive malignancy with a critical need for novel therapies. Our goal was to determine whether PARP inhibition could sensitize SCLC cells to ionizing radiation (IR) and if so, to determine the contribution ...
J. Laird   +6 more
semanticscholar   +1 more source

Harnessing Phytochemicals for Brain Cancer Therapy: Insights Into Medulloblastoma and Glioblastoma Treatment

open access: yesPhytochemical Analysis, EarlyView.
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek   +3 more
wiley   +1 more source

A review of preoperative chemoradiotherapy for lower rectal cancer

open access: yesJournal of the Anus, Rectum and Colon, 2017
In Western countries, rectal cancer has been treated by chemoradiotherapy (CRT) for several decades now, and good local control has been reported. However, Japanese guidelines did not strongly recommend CRT, because CRT is only useful for achieving local
Naohito Beppu   +2 more
doaj   +1 more source

Radiosensitization of noradrenaline transporter-expressing tumour cells by proteasome inhibitors and the role of reactive oxygen species [PDF]

open access: yes, 2013
Background The radiopharmaceutical 131I-metaiodobenzylguanidine (131I-MIBG) is used for the targeted radiotherapy of noradrenaline transporter (NAT)-expressing neuroblastoma.
Babich, J.W.   +4 more
core   +3 more sources

A new perspective on cancer treatment: the interaction and application prospect between ICIs and radiotherapy

open access: yesPrecision Radiation Oncology, EarlyView.
The combination of immune checkpoint inhibitors (ICIs) and radiotherapy synergistically enhances efficacy through an “antigen release‐immune activation” closed‐loop mechanism, significantly improving outcomes in solid tumors (e.g., lung cancer, melanoma).
Guiling Song   +5 more
wiley   +1 more source

Comparison of vinorelbine with cisplatin in concomitant chemoradiotherapy in head and neck carcinoma

open access: yesIndian Journal of Medical and Paediatric Oncology, 2010
Aim: Head and neck cancer is one of the most commonly occurring malignancies in the world. In India, the most commonly occurring head and neck cancers are those of the oral cavity and the pharynx.
Devleena   +3 more
doaj  

Impact of dietary ingredients on radioprotection and radiosensitization: a comprehensive review

open access: yesAnnals of Medicine
Radiation exposure poses significant health risks, particularly in radiotherapy and nuclear accidents. Certain dietary ingredients offer potential radioprotection and radiosensitization.
Md. Monirul Islam   +5 more
doaj   +1 more source

Autotaxin inhibition with PF8380 enhances the radiosensitivity of human and murine glioblastoma cell lines

open access: yesFrontiers in Oncology, 2013
Purpose: Glioblastoma multiforme (GBM) is an aggressive primary brain tumor that is radio-resistant and recurs despite aggressive surgery, chemo and radiotherapy.
Sandeep R Bhave   +16 more
doaj   +1 more source

Radiotherapy for cancer using X-ray fluorescence emitted from iodine [PDF]

open access: yes, 2017
Radiation treatment is popular and the apparatus is already available in many hospitals. Conventional radiation treatment by itself is not sufficient to achieve complete cure.
Ito Hiromu   +3 more
core   +1 more source

Home - About - Disclaimer - Privacy