Results 141 to 150 of about 73,957 (300)
Trajectories of Pontine Volume in Patients with Multiple System Atrophy
Movement Disorders, Volume 40, Issue 7, Page 1369-1378, July 2025.Abstract Objectives
To investigate trajectories of regional brain volume changes in multiple system atrophy (MSA) and their potential utility as surrogate markers of disease progression in the cerebellar subtype (MSA‐C). Background
Reliable biomarkers for tracking disease progression in MSA are urgently needed.Kazuya Kawabata, Florian Krismer, Mizuki Ito, Kazuhiro Hara, Epifanio Bagarinao, Vincent Beliveau, Patrice Péran, Germain Arribarat, Anne Pavy‐Le Traon, Wassilios G. Meissner, Alexandra Foubert‐Samier, Margherita Fabbri, Mark Forrest Gordon, Aya Ogura, Masahisa Katsuno, Olivier Rascol, Christoph Scherfler, Klaus Seppi, Hirohisa Watanabe, Werner Poewe +19 morewiley +1 more sourceTranscutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Parkinson's Disease: Results from a Phase II Randomized Control Trial (STRIPE)
Movement Disorders, Volume 40, Issue 7, Page 1291-1296, July 2025.Abstract Background
Lower urinary tract symptoms (LUTS) are common Parkinson's disease (PD), causing great impact. Objective
The goal was to undertake a phase II randomized control trial of transcutaneous tibial nerve stimulation (TTNS) delivered by Geko device for LUTS related to overactive bladder (OAB) in PD, an easy to use of the shelf solution ...Matthew D. Smith, Gabriella E. Portlock, Anisha Cullen, Anahita Nodehi, Marcus J. Drake, Yoav Ben‐Shlomo, Emily J. Henderson +6 morewiley +1 more sourceTreatment Selection and Prioritization for the EJS ACT‐PD MAMS Trial Platform
Movement Disorders, Volume 40, Issue 7, Page 1307-1317, July 2025.Abstract Background
There are currently no disease‐modifying therapies (DMTs) registered for Parkinson's disease (PD). The Edmond J. Safra Accelerating Clinical Trials in Parkinson Disease (EJS ACT‐PD) initiative will expedite clinical assessment of putative DMTs through a multi‐arm multistage (MAMS) trial, testing several treatments against a common ...Cristina Gonzalez‐Robles, Dilan Athauda, Thomas R. Barber, Roger A. Barker, David T. Dexter, Susan Duty, Romy Ellis‐Doyle, Sonia Gandhi, Joel Handley, Edwin Jabbari, Keith Martin, Kevin McFarthing, Georgia Mills, Heather Mortiboys, Stephen Mullin, Rebecca Petty, Esther Sammler, Paula Scurfield, Simon R.W. Stott, George K. Tofaris, Li Wei, Caroline H. Williams‐Gray, Alan Wong, Marie‐Louise Zeissler, Richard K. Wyse, Camille B. Carroll, Thomas Foltynie, Oliver Bandmann, Anthony H.V. Schapira, on behalf of the EJS ACT‐PD Consortium, Thomas Foltynie, Camille B Carroll, Roger Barker, James Carpenter, Yoav Ben‐Shlomo, Mark Edwards, Alan Whone, Carl Counsell, Caroline S Clarke, Matthew Burnell, Kate Hockey, Anna Jewell, Priti Gros, Tom Barber, Anette Schrag, Rimona S Weil, Caroline H Williams‐Gray, Michele T Hu, Lynn Rochester, Paola Piccini, Henrik Zetterberg, Alastair Noyce, Michael Lawton, Ashwani Jha, Brook Huxford, Shlomi Haar Millo, K. Ray Chaudhuri, Carroll Siu, Michèle Bartlett, Kuhan Pushparatnam, Daniel van Wamelen, Anthony HV Schapira, Oliver Bandmann, Simon Stott, George Tofaris, Esther Sammler, Heather Mortiboys, Li Wei, Alan Wong, Susan Duty, David Dexter, Edwin Jabbari, Stephen Mullin, Huw Morris, David Breen, Christian Lambert, Prasad Korlipara, Monty Silverdale, Kailash Bhatia, Alison Yarnall, Raj Khengar, Helen Collins, Fleur Hudson, Rebecca Croucher, Sandra Bartolomeu‐Pires, Veena Agarwal, Jennifer Allison, Jodie Forbes, Alex Edwards, Sheila Wonnacott, Dilan Athauda, Joy Duffen, Sonia Gandhi, Emily Henderson, Jen Black, Karen Matthews, Vince Greaves, Eric Deeson, Laurel Miller, Joel Handley, Helen Matthews, Kevin McFarthing, Amit Batla, Nikul Bakshi, Miriam Parry, Natasha Ratcliffe, Cheney Drew, Naveena Kapur, Anaya Navangul, Shafaq Ali, Katherine Fletcher, Claire Bale, Cristina Gonzalez‐Robles, Marie‐Louise Zeissler, Georgia Mills, Romy Ellis‐Doyle, Sally Collins, Rebecca Petty +117 morewiley +1 more sourceNeuronal α‐Synuclein Disease Stage Progression over 5 Years
Movement Disorders, Volume 40, Issue 7, Page 1318-1330, July 2025.Abstract Background
Neuronal α‐synuclein disease (NSD) is defined by the presence of an in vivo biomarker of neuronal alpha‐synuclein (n‐asyn) pathology. The NSD integrated staging system (NSD‐ISS) for research describes progression across the disease continuum as stages 0 to 6.Tanya Simuni, Caroline Gochanour, Anuprita R. Nair, Michael C. Brumm, Christopher Coffey, Kathleen L. Poston, Lana M. Chahine, Daniel Weintraub, Caroline M. Tanner, Paulina Gonzalez‐Latapi, Catherine M. Kopil, Yuge Xiao, Sohini Chowdhury, Tien Dam, Gennaro Pagano, Diane Stephenson, Andrew Siderowf, Billy Dunn, Kenneth Marek, on behalf of the NSD Working Group the Parkinson's Progression Markers Initiative, Kenneth Marek, Caroline Tanner, Tanya Simuni, Andrew Siderowf, Douglas Galasko, Lana Chahine, Christopher Coffey, Kalpana Merchant, Kathleen Poston, Roseanne Dobkin, Tatiana Foroud, Brit Mollenhauer, Dan Weintraub, Ethan Brown, Karl Kieburtz, Mark Frasier, Todd Sherer, Sohini Chowdhury, Roy Alcalay, Aleksandar Videnovic, Duygu Tosun‐Turgut, Werner Poewe, Susan Bressman, Jan Hammer, Raymond James, Ekemini Riley, John Seibyl, Leslie Shaw, David Standaert, Sneha Mantri, Nabila Dahodwala, Michael Schwarzschild, Connie Marras, Hubert Fernandez, Ira Shoulson, Helen Rowbotham, Paola Casalin, Claudia Trenkwalder, Todd Sherer, Sohini Chowdhury, Mark Frasier, Jamie Eberling, Katie Kopil, Alyssa O'Grady, Maggie McGuire Kuhl, Leslie Kirsch, Tawny Willson, Emily Flagg, Tanya Simuni, Bridget McMahon, Craig Stanley, Kim Fabrizio, Dixie Ecklund, Trevis Huff, Tatiana Foroud, Laura Heathers, Christopher Hobbick, Gena Antonopoulos, John Seibyl, Kathleen Poston, Christopher Coffey, Chelsea Caspell‐Garcia, Michael Brumm, Brit Mollenhauer, Doug Galasko, Kalpana Merchant, Andrew Singleton, Tatiana Foroud, Thomas Montine, Caroline Tanner, Carlie Tanner, Ethan Brown, Lana Chahine, Roseann Dobkin, Monica Korell, Charles Adler, Roy Alcalay, Amy Amara, Paolo Barone, Bastiaan Bloem Susan Bressman, Kathrin Brockmann, Norbert Brüggemann, Lana Chahine, Kelvin Chou, Nabila Dahodwala, Alberto Espay, Stewart Factor, Hubert Fernandez, Michelle Fullard, Douglas Galasko, Robert Hauser, Penelope Hogarth, Shu‐Ching Hu, Michele Hu, Stuart Isaacson, Christine Klein, Rejko Krueger, Mark Lew, Zoltan Mari, Connie Marras, Maria Jose Martí, Nikolaus McFarland, Tiago Mestre, Brit Mollenhauer, Emile Moukheiber, Alastair Noyce, Wolfgang Oertel, Njideka Okubadejo, Sarah O'Shea, Rajesh Pahwa, Nicola Pavese, Werner Poewe, Ron Postuma, Giulietta Riboldi, Lauren Ruffrage, Javier Ruiz Martinez, David Russell, Marie H. Saint‐Hilaire, Neil Santos, Wesley Schlett, Ruth Schneider, Holly Shill, David Shprecher, Tanya Simuni, David Standaert, Leonidas Stefanis, Yen Tai, Caroline Tanner, Arjun Tarakad, Eduardo Tolosa, Aleksandar Videnovic, Susan Ainscough, Courtney Blair, Erica Botting, Isabella Chung, Kelly Clark, Ioana Croitoru, Kelly DeLano, Iris Egner, Fahrial Esha, May Eshel, Frank Ferrari, Victoria Kate Foster, Alicia Garrido, Madita Grümmer, Bethzaida Herrera, Ella Hilt, Chloe Huntzinger, Raymond James, Farah Kausar, Christos Koros, Yara Krasowski, Dustin Le, Ying Liu, Taina M. Marques, Helen Mejia Santana, Sherri Mosovsky, Jennifer Mule, Philip Ng, Lauren O'Brien, Abiola Ogunleye, Oluwadamilola Ojo, Obi Onyinanya, Lisbeth Pennente, Romina Perrotti, Michael Pileggi, Ashwini Ramachandran, Deborah Raymond, Jamil Razzaque, Shawna Reddie, Kori Ribb, Kyle Rizer, Janelle Rodriguez, Stephanie Roman, Clarissa Sanchez, Cristina Simonet, Anisha Singh, Elisabeth Sittig, Barbara Sommerfeld, Angela Stovall, Bobbie Stubbeman, Alejandra Valenzuela, Catherine Wandell, Diana Willeke, Karen Williams, Dilinuer Wubuli +205 morewiley +1 more sourceRepeat Expansions with Small TTTCA Insertions in MARCHF6 Cause Familial Myoclonus without Epilepsy
Movement Disorders, Volume 40, Issue 7, Page 1401-1408, July 2025.Abstract Background
Familial adult myoclonus epilepsy (FAME) is a rare autosomal dominant disorder caused by the same intronic TTTTA/TTTCA repeat expansion in seven distinct genes. TTTTA‐only expansions are benign, whereas those containing TTTCA insertions are pathogenic.Theresa Kühnel, Elsa Leitão, Renate Lunzer, Fabian Kilpert, Sabine Kaya, Claudia Del Gamba, Kelly Astudillo, Steven Frucht, Marion Simonetta‐Moreau, Eric Bieth, Iris Unterberger, Giulietta Maria Riboldi, Christel Depienne +12 morewiley +1 more source
