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Radiosynovectomy is effective in thumb basal joint arthritis
Annals of Nuclear Medicine, 2021Radiosynovectomy (RSO) describes the internal low-dose radiotherapy of the synovia via intra-articular administration of small radioactive particles. Since the introduction of biologics, the main aetiology of arthritic joints for RSO changed to mostly osteoarthritis with concordant change in typically affected joints.
Knut Liepe, Marcel Baehr
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Monitoring the genotoxic effects of radiosynovectomy with Re-186 in paediatric age group undergoing therapy for haemophilic synovitis [PDF]
Haemophilia, 2007 Purpose: The aim of this study was to investigate the genotoxic effect on the peripheral blood lymphocytes potentially induced by Re-186 in paediatric age group undergoing radiosynovectomy for haemophilic synovitis, by using chromosomal aberration ...
Sanli, Y. +9 more
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Blood Coagulation & Fibrinolysis, 2013
Haemophilic arthropathy occurs due to recurrent bleeding into joints leading to swelling, inflammation, destruction of cartilage and bone, and development of arthritis. Although prophylactic replacement therapy assists in preventing arthropathy, it is not always adequate or affordable. Radiosynovectomy is a minimally invasive intervention for treatment
Angeli G, Rampersad +5 more
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Haemophilic arthropathy occurs due to recurrent bleeding into joints leading to swelling, inflammation, destruction of cartilage and bone, and development of arthritis. Although prophylactic replacement therapy assists in preventing arthropathy, it is not always adequate or affordable. Radiosynovectomy is a minimally invasive intervention for treatment
Angeli G, Rampersad +5 more
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Radiosynovectomy's clinical applications and cost effectiveness: A review
Seminars in Nuclear Medicine, 1997It is apparent that from the work of the authors and many others, including the work of Rivard, Sledge, Zuckerman, among others, that radiosynovectomy has an important role to play in providing effective treatment of affected joints associated with rheumatoid arthritis and other forms of arthritis as well as the hemophiliac joint.
M E, Siegel, H J, Siegel, J V, Luck
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Radiosynovectomy in Children with Congenital Haemostatic Defects
Blood, 2008Abstract Aims: To evaluate the clinical benefits of radiosynovectomy (RS) in children with congenital coagulative disorders, reduce bleeds and improve progression free survival (PFS). Methods: 35 patients aged 7 to 17 yrs, (mean age 12.6 yrs) were included in the study. 29 had haemophilia A, (4 with inhibitor factor VIII),
Michal Matysiak +5 more
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Radiosynovectomy in rheumatology, orthopedics, and hemophilia.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2005Radiosynovectomy (RSV) is a local intraarticular injection of radionuclides in colloidal form for radiotherapy. First used by Fellinger et al. in 1952, the technique has now been applied for more than 50 y for treatment of resistant synovitis of individual joints after failure of long-term systemic pharmacotherapy and intraarticular steroid injections.
Peter, Schneider +2 more
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[Radiosynovectomy with dysprosium-165 iron hydroxide].
Acta medica Austriaca, 1993Treatment of chronic rheumatoid synovitis (RS) is directed to control the inflammatory process causing pain and disability. Radiation synovectomy is suggested to be an alternative to surgical treatment, but its clinical use has been restricted because of significant leakage (> 10%) associated with the use of the standard radionuclide 90-Yttrium (used ...
C, Pirich +8 more
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Phosphate-32 Colloid Radiosynovectomy in Hemophilia
Clinical Orthopaedics and Related Research, 2001Radiosynovectomy offers a potentially effective, minimally invasive option for patients with chronic hemarthrosis and synovitis. The long-term outcome of patients with hemophilia who were treated with phosphate-32 chromic phosphate radiosynovectomy was evaluated. One hundred twenty-five procedures in 81 patients were done.
H J, Siegel +3 more
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Development of 90Y-chitosan as a new agent for radiosynovectomy
Journal of Radioanalytical and Nuclear Chemistry, 2015Radiosynovectomy (RSV) has been applied as an effective treatment to the patients with resistant synovitis for more than 50 years. In this research, 90Y-chitosan complex was developed as a new agent for use in RSV. 90Y was obtained from an electrochemical 90Y/90Sr generator. 90Y-chitosan complex was produced with radiochemical purity of higher than 99 %
Samaneh Zolghadri +4 more
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