Preparation of 191Os–phytate, an in-vivo radionuclide generator, for radiosynovectomy application [PDF]
191Os is a parent radionuclide with a 15.4 d half-life. It decays by beta emission to 191mIr, which is a radionuclidewith a 4.96s half-life. It decays by the isomeric transition to stable 191Ir, emitting a 129-keV gamma photon.
Leila Moghaddam-Banaem +3 more
doaj +3 more sources
Efficacy of radiation synovectomy (radiosynovectomy or radiosynoviorthesis) with yttrium-90 in exudative inflammation of synovial membrane of knee joints in patients with rheumatic diseases – preliminary report [PDF]
Objectives : Hypertrophic and exudative synovitis of the knee is one of the earliest symptoms in rheumatic diseases. In the case of pharmacotherapy failure, other methods which directly remove the inflamed synovial membrane are used – synovectomies ...
Joanna Zalewska +5 more
doaj +2 more sources
Radiosynovectomy of ankle joint synovitis in juvenile rheumatoid arthritis treated with rhenium-188 tin colloid and imaging with SPECT/CT [PDF]
Rheumatoid arthritis is a chronic disease that is mainly characterized by asymmetric erosive synovitis, particularly affecting peripheral joints. Radiation synovectomy, or radiosynovectomy, was first described in 1950s as an adjuvant treatment for ...
Koramadai K Kamaleshwaran +5 more
doaj +2 more sources
Radionuclide synovectomy – essentials for rheumatologists [PDF]
Radionuclide synovectomy is a minimally invasive method of treating persistent joint inflammation. It involves intra-articular injection of radioactive colloids which induce necrosis and fibrosis of hypertrophic synovial membrane.
Marek M. Chojnowski +2 more
doaj +2 more sources
Radiosynovectomy of Proximal Interphalangeal Joint Synovitis in Rheumatoid Arthritis Treated with Rhenium-188 Labeled Tin-colloid and Imaging with Single-photon Emission Computerized Tomography/Computed Tomography: A First Case Report [PDF]
Rheumatoid arthritis (RA) is a chronic disease that is mainly characterized by the asymmetric erosive synovitis, particularly affecting peripheral joints.
Koramadai Kamaleshwaran +6 more
doaj +2 more sources
The use of radiosynovectomy in patients with juvenile idiopathic arthritis. Assessment of treatment efficacy and safety [PDF]
Agnieszka Gazda +6 more
doaj +2 more sources
Development of 166Ho-phytate Complex for Radiosynovectomy [PDF]
(66)Ho-chloride was obtained by bombardment of natural Ho(NO3)3 dissolved in acidic media using thermal neutron flux (4-5 × 10(13) n.cm(-2).s(-1)).(166)Ho-holmium chloride (185 MBq) was used successfully for preparation of (166)Ho-phytate complex with high radiochemical purity (>99.9 %, ITLC, MeOH: H2O: acetic acid, 4: 4: 2, as mobile phase).
Amir R, Jalilian +4 more
openaire +4 more sources
Treatment response evaluation using Yttrium-90 in patients with rheumatoid arthritis of knee joint
For radiosynovectomy, we have measured the retention time of yttrium-90 (90Y) hydroxyapatite (particle size 1–10 μm) within the knee joint space and evaluated the treatment responses in knees with rheumatoid arthritis.
Jong Kim, Wi Kim, Yong Pak
doaj +2 more sources
Radiosynovectomy for the Treatment of Chronic Hemophilic Synovitis: An Old Technique, but Still Very Effective. [PDF]
A radiosynovectomy (RS) should be indicated when recurrent articular bleeds related to chronic hemophilia synovitis (CHS) exist, established by clinical examination, and confirmed by imaging techniques that cannot be constrained with hematological ...
Rodriguez-Merchan EC +4 more
europepmc +2 more sources
A Novel Activatable Nanoradiosensitizer for Second Near-Infrared Fluorescence Imaging-Guided Safe-Dose Synergetic Chemo-Radiotherapy of Rheumatoid Arthritis. [PDF]
In this work, a novel activatable nanoradiosensitizer (IRnR‐40) is developed, based on encapsulating the clinically approved drugs of cisplatin and indocyanine green in gelatin to achieve precisely responsive second near‐infrared fluorescence imaging‐guided safe chemo‐radiosynovectomy for the advanced stage of RA, which provides a new paradigm for ...
Jin Y +11 more
europepmc +2 more sources

