Results 71 to 80 of about 164,482 (307)

Incidence of radiation toxicity in cervical cancer and endometrial cancer patients treated with radiotherapy alone versus adjuvant radiotherapy

, 2012
AimThe study was made to evaluate early and late toxicity in a diversified group of patients receiving definitive or adjuvant radiotherapy in terms of clinical diagnosis and treatment methods.BackgroundRadiotherapy is a standard way of treatment in ...
Wareńczak-Florczak, Żaneta; Greater Poland Cancer Centre, Department of Gynaecological Radiotherapy and Oncology, Garbary Street 15, 61-866 Poznan, Poland, Roszak, Andrzej; Greater Poland Cancer Centre, Department of Gynaecological Radiotherapy and Oncology, Garbary Street 15, 61-866 Poznan, Poland; Department of Electroradiology, University of Medical Sciences, Poznan, Poland, Bratos, Krystyna; Greater Poland Cancer Centre, Department of Gynaecological Radiotherapy and Oncology, Garbary Street 15, 61-866 Poznan, Poland, Milecki, Piotr; Department of Electroradiology, University of Medical Sciences, Poznan, Poland; Greater Poland Cancer Centre, Department of Radiation Oncology, Garbary Street 15, 61-866 Poznan, Poland   +3 more
core   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Subgroup analysis of OS stratified by adjuvant radiotherapy and chemoradiotherapy.

, 2020
A, adjuvant radiotherapy; B, adjuvant chemoradiotherapy.
Lei Wang (6656), Nanping Lin (8478612), Manjun Deng (8478615), Qiao Ke (8478609), Jingfeng Liu (1392460), Yongyi Zeng (1392457)   +5 more
core   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Adjuvant radiotherapy for locally advanced upper tract urothelial carcinoma [PDF]

, 2016
There is relatively little literature on adjuvant radiotherapy after radical nephroureterectomy with bladder cuff excision (RNU) for patients with upper tract urothelial carcinoma (UTUC).
Chang, Ying-Hsu, Shindel, Alan W, Lai, Chia-Hsuan, Huang, Yun-Ching, Chiu, Kuo-Hsiung   +4 more
core   +1 more source

The outcomes and quality of life of young patients undergoing adjuvant radiotherapy versus non-radiotherapy following surgery treating early FIGO stage cervical squamous cell cancer in southwestern China

Scientific Reports, 2020
Background: The incidence of cervical cancer in young women is rising, and squamous cell carcinoma makes up a great percentage of the histological types.
Lingyun Yang, Jialing Yuan, Xi Zeng, Mingrong Xi, Hongjing Wang   +4 more
doaj   +1 more source

The results of adjuvant radiotherapy in endometrial carcinoma

Gynecological Endocrinology, 2009
To examine the clinical characteristics and treatment outcomes in patients with endometrial cancer receiving adjuvant radiotherapy.A total of 157 patients who received postoperative radiotherapy (RT) between 1999 and 2008 were evaluated, retrospectively. The mean age was 59 years (34-82). All patients received RT following surgery.
Aylin Fidan, Korcum, Evrim, Duman, Gamze, Aksu   +2 more
openaire   +2 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Adjuvant radiotherapy in patients with vulvar cancer and one intra capsular lymph node metastasis is not beneficial

, 2009
Aim of the study. The aim of the study was to analyze the benefit from adjuvant radiotherapy in patients with vulvar cancer and a single positive node without extra capsular spread. Materials and methods.
van der Zee, A. G. J., Stalpers, L. J. A., Groenen, S. M. A., van der Velden, J., Oonk, M. H. M., Burger, M. P. M., Ansink, A. C., Fons, G.   +7 more
core   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source