Results 221 to 230 of about 42,443 (305)

The Evolving Role of Radiation Oncology in the Management of Uterine Cervical Carcinoma: A State-of-the-Art Review for Non-Radiation Oncologists. [PDF]

Life (Basel)
Flores-Balcázar CH, Matsumoto-Palomares SA, Chávez-Zaldívar DI, Marin-Trinidad AI, Castro-Pérez FG, Cetina-Pérez LDC.   +5 more
europepmc   +1 more source

Targeting Ikaros and Aiolos: Next‐Generation Cereblon E3 Ligase Modulators in MM

European Journal of Haematology, EarlyView.
The graphical abstract illustrates the mechanism of action of cereblon E3 ligase modulators (CELMoDs) in multiple myeloma, highlighting cereblon‐mediated degradation of IKZF1 and IKZF3. Compared with classical immunomodulatory drugs (IMiDs), CELMoDs induce deeper IKZF1/3 depletion, leading to more pronounced suppression of the IRF4–MYC survival axis ...
Maria Eugenia Alvaro, Enrica Antonia Martino, Santino Caserta, Mamdouh Skafi, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Improvement of Dosimetry Planning in 3D Conformal Radiotherapy for Breast Cancer With Lymph Nodes Using the High-Tangential Tilted-Supraclavicular Technique. [PDF]

Int J Breast Cancer
Moussallem M.
europepmc   +1 more source

Targeting the Menin–KMT2A Axis in Acute Leukemia: From Epigenetic Dependency to Clinical Translation

European Journal of Haematology, EarlyView.
ABSTRACT Acute leukemias characterized by a shared epigenetic dependency on the menin–KMT2A axis rely on aberrant HOX‐driven transcriptional programs that sustain leukemic self‐renewal and impair differentiation. This dependency is most evident in KMT2A‐rearranged and NPM1‐mutated acute myeloid leukemia (AML), but also extends to other HOX‐dependent ...
Antonella Bruzzese, Ernesto Vigna, Enrica Antonia Martino, Santino Caserta, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Mamdouh Skafi, Nicola Amodio, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Epilepsy in Patients with Cerebral Radiation Necrosis: A Scoping Review. [PDF]

Medicina (Kaunas)
Laman PVQ, Scheepens JCC, Kroon LL, Vos MJ, Brandsma D, Koekkoek JAF.   +5 more
europepmc   +1 more source

An update on the landscape of collagen bioactive fragments

The FEBS Journal, EarlyView.
The remodeling of the extracellular matrix releases collagen bioactive fragments, which exert molecular functions and regulate numerous biological processes via several signaling pathways. Here, we summarize the latest findings describing the roles of major bioactive fragments from collagens I, IV, VI, and XVIII in various physiological and ...
Sylvie Ricard‐Blum, Julie Fradette
wiley   +1 more source

High-precision radiotherapy achieves excellent long-term control and preserves function in pediatric craniopharyngioma-Subset analysis of a randomized trial. [PDF]

Neuro Oncol
Jalali R, Ghosh S, Chatterjee A, Goswami S, Shah N, Dutta D, Krishna U, Gupta T, Goda JS.   +8 more
europepmc   +1 more source

3D virtual histology demonstrates tumour connectivity in spread through air spaces (STAS) of non‐small cell lung cancer

Histopathology, EarlyView.
STAS‐positive lung nodules were analysed using histology, clinical CT, and synchrotron‐based μCT. μCT enables 3D spatial insights of STAS clusters which appear consistently connected to alveolar or vascular structures, suggesting non‐random distribution.
Giulia Saccomano, Francesco Brun, Fulvia Martellani, Cristina Bottin, Stefano Lovadina, Marina Troian, Maria Assunta Cova, Elisa Baratella   +7 more
wiley   +1 more source

Anesthetic Strategy for 30 Radiotherapy Sessions in a Child With Autism Spectrum Disorder (ASD) and Severe Behavioral Dysregulation: A Case Report. [PDF]

Cureus
Imbelloni L, Rivoli A, Lemos Neto SV, Santos MV, SantaRosa AA, Modolo NP.   +5 more
europepmc   +1 more source

Reference Values for Pulse Oximetry Testing in Permanent Teeth: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Pulse oximetry is an accurate diagnostic method for assessing the condition of the dental pulp; however, the normal oxygen saturation levels for each tooth type are yet to be clearly defined. Objectives This systematic review and meta‐analysis aims to answer the question: What are the reference values for pulse oximetry testing in ...
Lilian Tietz, Theodoro Weissheimer, Cassiano Kuchenbecker Rösing, Marcus Vinicius Reis Só   +3 more
wiley   +1 more source