Results 101 to 110 of about 128,967 (306)

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

Advanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez, Jose I. Garcia‐Peiro, Jose L. Hueso, Eduardo Caleiras, Laura Notario, Felipe Hornos, Pilar Martin‐Duque, Antonio De la Vieja, Jesus Santamaria   +8 more
wiley   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

Plasmonic Nanomachines: Creating Local Potential Gradients and Motions

Advanced Materials, EarlyView.
Plasmonic nanomachines can generate optical, thermal, and chemical potential gradients to drive directional rectilinear, rotational, and twisting motions at the nanometer scale. The integration of multimodal plasmonic forces with functional materials and programmed structural distortions enables precise spatiotemporal actuation, thereby providing a ...
Yoonhee Kim, Soohyun Ji, Donghyun Choi, Jwa‐Min Nam   +3 more
wiley   +1 more source

Fast and precise dose estimation for very high energy electron radiotherapy with graph neural networks

Frontiers in Physics
IntroductionExternal beam radiotherapy (RT) is one of the most common treatments against cancer, with photon-based RT and particle therapy being commonly employed modalities.
Lorenzo Arsini, Lorenzo Arsini, Barbara Caccia, Andrea Ciardiello, Andrea Ciardiello, Angelica De Gregorio, Angelica De Gregorio, Gaia Franciosini, Gaia Franciosini, Stefano Giagu, Stefano Giagu, Susanna Guatelli, Susanna Guatelli, Annalisa Muscato, Annalisa Muscato, Francesca Nicolanti, Francesca Nicolanti, Jason Paino, Jason Paino, Angelo Schiavi, Carlo Mancini-Terracciano, Carlo Mancini-Terracciano   +21 more
doaj   +1 more source

Nanozymes at the Bio‐Nano Interface: From Synthesis, Defect Engineering, Catalytic Behavior in Biological Microenvironments, and Biosafety Implications

Advanced Materials Interfaces, EarlyView.
Nanozymes (NZs) have emerged as versatile artificial enzymes with tunable catalytic properties driven by atomic coordination, defect engineering, and surface chemistry. This review presents a bio–nano interface framework linking synthesis strategies, structural design, and catalytic behavior within complex biological microenvironments.
Karen Guadalupe Quintero‐Garrido, Aída Jimena Velarde‐Salcedo, Alejandro López‐Amador, Noé Arjona, Citlali Uitz Toalá, Carmen Gonzalez, Beatriz Liliana España‐Sánchez   +6 more
wiley   +1 more source

A Dual-Beam Irradiation Facility for a Novel Hybrid Cancer Therapy

, 2012
In this paper we present the main ideas and discuss both the feasibility and the conceptual design of a novel hybrid technique and equipment for an experimental cancer therapy based on the simultaneous and/or sequential application of two beams, namely a
A Doria, A Rosen, AG Pakhomov, AR Orlando, B Born, BS Jang, C Furse, C Yu, D Satoh, DT Pooley, E Bründermann, E Giovenale, EA Nanni, G Andocs, GJ Hyland, GJ Wilmink, GJ Wilmink, H Frohlich, H Kamada, H Kamada, J Wang, JR Reimers, K Mileva, MR Scarfì, Norio Miyoshi, P Wusta, PH Siegel, R Barth, RF Barth, S Banik, S Sabchevski, S Sabchevski, Shintaro Ishiyama, Svilen Petrov Sabchevski, T Idehara, T Idehara, T Idehara, T Sato, T Tatsukawa, T Tatsukawa, T Tatsukawa, T Tatsukawa, TA Buchholz, Toshiaki Tatsukawa, Toshitaka Idehara, Y Nakagawa   +45 more
core   +1 more source

Advances in Halide Perovskites for Photon Radiation Detectors

Advanced Materials Technologies, EarlyView.
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang, Jieqi Wang, Xiaojun Cui, Carsten Ronning   +3 more
wiley   +1 more source

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

A compact, lightweight, variable-energy cyclotron for conventional and FLASH ion beam radiotherapy

Frontiers in Oncology
IntroductionThe advantage of ion beam radiotherapy for cancer lies in its low dose proximal and distal to the tumor, owed to an energy-dependent depth-dose profile, the Bragg-peak. However, conventional techniques to achieve different energies often rely
D. Winklehner, J. V. Minervini, L. Bromberg, E. Forton, J. Mandrillon, P. C. Michael, A. Radovinsky   +6 more
doaj   +1 more source