Results 181 to 190 of about 73,118 (265)

Somatic cell reprogramming for Parkinson's disease treatment

open access: yesIbrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Exposure and impact: highlights from the second scientific conference and recent activities of the International Society of Radiation Epidemiology and Dosimetry (ISoRED). [PDF]

open access: yesJ Radiol Prot
Harbron R   +17 more
europepmc   +1 more source

Piezoelectric Materials in Medical Ultrasound: A Comprehensive Review From Fundamentals to Translational Prospects

open access: yesInformation &Functional Materials, EarlyView.
Piezoelectric materials are reviewed as active platforms for medical ultrasound, bridging electromechanical fundamentals, transducer architectures, and biomedical applications. Material–device co‐design is emphasized as the key to high‐performance diagnosis, therapy, monitoring, wearable ultrasound, and emerging ultrasound‐responsive functions ...
Jianan Li, Qing Wan
wiley   +1 more source

Sizing and concentration analysis of cfDNA using Biabooster technology: Results from a prospective plasma‐based collection of 77 patients with locally advanced unresectable esophageal cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? This study introduces a novel approach for detecting locally advanced esophageal carcinoma using cell‐free DNA (cfDNA) analysis through a highly sensitive fragmentome assay. Unlike traditional sequencing‐based methods that are limited by the absence of specific mutations in esophageal tumors, our method offers an alternative by quantifying ...
Anouchka Modesto   +21 more
wiley   +1 more source

Nutritional prehabilitation in head and neck cancer patients (PreHead) - A randomized controlled trial study protocol. [PDF]

open access: yesPLoS One
Sijbrands D   +9 more
europepmc   +1 more source

Combination of Lenvatinib and Antibiotics: A Potential Approach to Enhance Sensitivity in Differentiated Thyroid Cancer

open access: yesInternational Journal of Cancer, EarlyView.
Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger   +13 more
wiley   +1 more source

Real-time energy measurement of clinical carbon ion beams using a cross-correlation time-of-flight method with parallel-plate chambers. [PDF]

open access: yesMed Phys
Kwon NH   +15 more
europepmc   +1 more source

Risk–Benefit of Phase 2 Monotherapy Trials in Adult Solid Cancers: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Cancer, EarlyView.
The therapeutic status of drug administration in phase 2 cancer trials is ambiguous, as these studies test efficacy without strong evidence of clinical benefit. Nonetheless, patients face meaningful risks. This review compared efficacy and safety of monotherapy drugs in phase 2 and phase 3 trials across six cancer types.
Charlotte Ouimet   +2 more
wiley   +1 more source

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