Results 11 to 20 of about 72,896 (217)

A review of the Best Practice in Radiation Oncology project from 2008 to 2018

open access: yesTechnical Innovations & Patient Support in Radiation Oncology, 2018
The European Society of Radiotherapy and Oncology (ESTRO)/International Atomic Energy Agency (IAEA) Best Practice in Radiation Oncology-a project to train RTT trainers has reached its ten year anniversary and will commence its fifth iteration in 2018 ...
Mary Coffey   +9 more
doaj   +1 more source

New insights on clinical perspectives of FLASH radiotherapy: from low- to very high electron energy

open access: yesFrontiers in Oncology, 2023
Radiotherapy (RT) is performed in approximately 75% of patients with cancer, and its efficacy is often hampered by the low tolerance of the surrounding normal tissues.
Stefano Ursino   +15 more
doaj   +1 more source

Kimura's Disease of the Orbit Successfully Treated with Radiotherapy Alone: A Case Report

open access: yesCase Reports in Ophthalmology, 2014
We performed radiotherapy in a 28-year-old patient with Kimura's disease of the orbit. Irradiation with 21.6 Gy was administered to the tumor bed with a single dose of 1.8 Gy in 5 weekly fractions delivered via a high-energy linear accelerator (6-MV X ...
Yoshio Monzen   +2 more
doaj   +1 more source

Dosimetry for New Radiation Therapy Approaches Using High Energy Electron Accelerators

open access: yesFrontiers in Physics, 2020
We have performed dosimetry studies using electron beams with energies up to 50 MeV, which exceed current clinical energy ranges and approaches the bottom end of the very high energy electron range. 50 MeV electron beams can reach deep-seated tumors.
Karolina Kokurewicz   +9 more
doaj   +1 more source

Electron and Photon Energy Spectra Outside of 6 MV X-ray Small Radiotherapy Field Edges Produced by a Varian iX Linac

open access: yesFrontiers in Physics, 2021
Due to the increase in the survival probability for patients treated with modern radiotherapy techniques to live enough for experimenting the late radiation effect, low dose outside the treatment volume becomes a concern.
Nahum Xicohténcatl-Hernández   +3 more
doaj   +1 more source

Photoneutron production mechanisms, their characteristics, and shielding strategies in high-energy linac environment: A review

open access: yesJournal of Radiation Research and Applied Sciences
Radiotherapy, a mainstay cancer treatment for patients worldwide, utilizes medical linear accelerators (linacs) with photon energies ranging from 4 MV to 25 MV. However, concerns arise at higher energies (>6 MV, particularly >10 MV).
Md Fakhar Uddin   +9 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Hydrogel-based approaches for radiation protection in radiotherapy

open access: yesRadiation Medicine and Protection
As one of the primary modalities for cancer treatment, radiotherapy (RT) utilizes high-energy radiation to eradicate cancer cells or inhibit tumor growth and is widely employed in clinical practice. However, while targeting malignant cells, radiation can
Mingliang Zhu   +4 more
doaj   +1 more source

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