Results 51 to 60 of about 72,896 (217)

Intrinsic Photoactive Star ZnPc–Poly(glutamate) Nanoplatforms for Multimodal Glioblastoma Therapy and Brain‐Targeted Delivery

Advanced Functional Materials, EarlyView.
An intrinsic photoactive star‐shaped zinc phtalocyanine‐poly(L‐glutamic acid) (ZnPc‐PGA) nanoplatform for multimodal glioblastoma (GBM) therapy and brain‐targeted elivery. A ZnPc‐PGA‐based multifunctional theranostic nanocarrier platform enables image‐guided, multimodal GBM therapy. ZnPc‐PGA nanocarriers support the integration of fluorescence imaging,
Amina Benaicha‐Fernández, Teodora Ranđelović, Ana Armiñán, Víctor Sebastián, Manuel Fuentes, Cristián Huck‐Iriart, Esther Masiá, Paula Carrascosa‐Marco, Pablo Juanes‐Velasco, Snežana Đorđević, Clara Bayona, Ignacio Ochoa, Maria Medel, Inmaculada Conejos‐Sánchez, María J. Vicent   +14 more
wiley   +1 more source

Treatment planning for very high energy electrons: Studies that indicate the potential of the modality

Physics and Imaging in Radiation Oncology
Background and purpose: Radiotherapy using Very High Energy Electrons (VHEE) has the potential to reduce dose to organs at risk compared to photons.
James L. Bedford, Uwe Oelfke
doaj   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Selenium‐Doped Nanoheterojunctions for Highly Efficient Cancer Radiosensitization

Advanced Science
Exploring efficient and low‐toxicity radiosensitizers to break through the bottleneck of radiation tolerance, immunosuppression and poor prognosis remains one of the critical developmental challenges in radiotherapy.
Rui Qiao, Zhongwen Yuan, Meijin Yang, Zhiying Tang, Lizhen He, Tianfeng Chen   +5 more
doaj   +1 more source

Proposal and Analysis of "Ternary" Model of Sensitization for Proton Therapy

Zhongguo yiliao qixie zazhi
In order to improve the biological effect of proton therapy, the authors first propose a new method of boron-based proton-enhanced radiotherapy in a " ternary " radiotherapy mode, based on the existing sensitizing effect of proton radiotherapy: i.e ...
Xiaowa WANG, Xufei WANG, Ning DU, Lan WANG   +3 more
doaj   +1 more source

MRI-Guided Radiotherapy for Prostate Cancer: a New Paradigm

Acta Clinica Croatica, 2022
Radiotherapy is one of the key treatment modalities for primary prostate cancer. During the last decade, significant advances were made in radiotherapy technology leading to increasing both physical and biological precision.
Jure Murgić, Marin Gregov, Iva Mrčela, Mirjana Budanec, Marco Krengli, Ana Fröbe, Pierfrancesco Franco   +6 more
doaj  

Advances in Halide Perovskites for Photon Radiation Detectors

Advanced Materials Technologies, EarlyView.
This work highlights recent progress in perovskite‐based photon radiation detectors, covering organic–inorganic hybrid, inorganic, lead‐free double, and vacancy‐ordered halide perovskites. Their detection performance is compared, material‐specific advantages and challenges are examined, and provides insight into current limitations and future ...
Liangling Wang, Jieqi Wang, Xiaojun Cui, Carsten Ronning   +3 more
wiley   +1 more source

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

Advanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin, Jie Yang, Yongcheng Li, Yuepeng Cai, Xiaosong Zhou, Ting Chen, Renfeng Dong   +6 more
wiley   +1 more source

Compact dose delivery of laser-accelerated high-energy electron beams toward radiotherapy applications

Physical Review Accelerators and Beams
The use of very high-energy electron (VHEE) beams for radiotherapy has been actively studied for over two decades due to their advantageous dose distribution, deep penetration depth, and great potential of ultrahigh dose-rate irradiation. Recently, laser-
Bing Zhou, Zhiyuan Guo, Yang Wan, Shuang Liu, Bo Peng, Jianfei Hua, Wei Lu   +6 more
doaj   +1 more source

Impact of Metallic Implants on Dose Distribution in Radiotherapy with Electrons, Photons, Protons, and Very-High-Energy Beams

Applied Sciences
Metallic implants in radiotherapy patients alter dose distributions due to their high density and unique composition, potentially compromising treatment precision.
Nicole Kmec Bedri, Milan Smetana, Ladislav Janousek   +2 more
doaj   +1 more source