Results 121 to 130 of about 36,702 (248)

Simultaneous integrated boost intensity-modulated radiotherapy for treatment of bone metastases: analysis of a breast cancer cohort. [PDF]

Acta Oncol
Marazzi F, Masiello V, Fabi A, Manfrida S, Corvari B, Lancellotta V, Mazzarella C, Longo S, De Angeli M, Moschella F, Di Leone A, Orlandi A, Bracci S, Colloca GF, Massaccesi M, Boldrini L, Tagliaferri L, Bria E, Masetti R, Franceschini G, Valentini V, Gambacorta MA, Cellini F.   +22 more
europepmc   +1 more source

Single‐Cell Analysis Clarifies Pathological Heterogeneity in Tenosynovial Giant Cell Tumor and Identifies Biomarkers for Predicting Disease Recurrence

Advanced Science, EarlyView.
MP3 tumor cells, a specific subpopulation of tumor cells in D‐TGCT, regulated the differentiation of CD34+ Fbs into MMP3+ Fbs and APOE+ Fbs through COL6A3 − (ITGAV + ITGB8) interaction. APOE+ Fbs activated IL‐1B+CCL20+ Mφs through the CXCL12/CXCR4 axis. IL‐1B+CCL20+ Mφs and MMP3+ Fbs participated in the local invasion of D‐TGCT.
Yubin Xie, Chen Chen, Fei Wu, Yiman Peng, Jing Su, Yang Zhao, Hongjie Huang, Zhong Alan Li, Yin Pei, Wencui Li, Yi He, Tianchen Xue, Chenxi Cao, Sui Peng, Xin Zhang, Weidong Song   +15 more
wiley   +1 more source

Potential Risk of Cognitive Impairment Due to Irradiation of Neural Structures in Locally Advanced Nasopharyngeal Cancer Treated by Curative Radiotherapy. [PDF]

Medicina (Kaunas)
Mireștean CC, Buzea CG, Zară AD, Iancu RI, Iancu DPT.   +4 more
europepmc   +1 more source

Camouflaged Nanozymes with Oxidation‐Promoting Activities Triggering Ferroptosis for Radio‐Immunotherapy

Advanced Science, EarlyView.
This study develops a cancer cell membrane‐coated nanozyme that enhances radiotherapy and reshapes the immunosuppressive microenvironment by generating oxygen in situ and disrupting tumor antioxidant defenses, offering a new strategy for breast cancer radioimmunotherapy.
Kun Qiao, Yongbiao Huang, Shipeng Ning, Meng Lyu, Jieqiong Xie, Shiyuan Zhang, Xiuxin Lu, Yuan Yu, Wei Jiang, Bo Liu, Kelong Fan, Tong Liu   +11 more
wiley   +1 more source

Impact of Neoadjuvant and Adjuvant Pleural Intensity-Modulated Radiotherapy in Multimodality Treatment for Malignant Pleural Mesothelioma. [PDF]

Thorac Cancer
Mosleh B, Schwarz S, Cho A, Sinn K, Steindl A, Zöchbauer-Müller S, Köstler WJ, Dieckmann K, Heilmann M, Widder J, Gompelmann D, Aigner C, Klikovits T, Hoda MA.   +13 more
europepmc   +1 more source

Targeting PFKFB4 Biomimetic Codelivery System Synergistically Enhances Ferroptosis to Suppress Small Cell Lung Cancer and Augments the Efficacy of Anti‐PD‐L1 Immunotherapy

Advanced Science, EarlyView.
In this study, a targeting PFKFB4 biomimetic codelivery system is developed to improve paclitaxel efficacy by inducing ferroptosis in SCLC. This system enhances immune cell infiltration and cytokine secretion, activating anti‐tumor immunity. Combined with anti‐PD‐L1, it boosts immune responses, offering a novel therapeutic strategy for overcoming ...
Xiang Liu, Jingjun He, Haoxuan Ying, Cuiying Chen, Chongyang Zheng, Peng Luo, Weiliang Zhu, Ting Wei, Bufu Tang, Jian Zhang   +9 more
wiley   +1 more source

Comparative dosimetric assessment of combined treatment modalities in cervical cancer radiotherapy for optimal organ protection. [PDF]

Radiat Environ Biophys
Gazsi I, Marcu LG.
europepmc   +1 more source

PRMT1‐Mediated SWI/SNF Complex Recruitment via SMARCC1 Drives IGF2BP2 Transcription to Enhance Carboplatin Resistance in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu, Wentao Zhang, Weiwei Liu, Zhao Ding, Ruijing Zhang, Yuefeng Han, Zihao Niu, Mengdie Zhang, Hui Li, Dapeng Li, Zixi Wang, Jie Peng, Yu Wu, Yanxun Han, Zihui Xie, Jing Wu, Liang Qin, Zhongdong Hu, Xu Chen, Yunlong Hu, Yehai Liu, Shiyin Ma, Xiaojun Zha   +22 more
wiley   +1 more source

Long-Term Patient-Reported Bowel and Urinary Quality of Life in Patients Treated with Intensity-Modulated Radiotherapy Versus Intensity-Modulated Proton Therapy for Localized Prostate Cancer. [PDF]

Curr Oncol
Gergelis KR, Bai M, Ma J, Routman DM, Stish BJ, Davis BJ, Pisansky TM, Whitaker TJ, Choo R.   +8 more
europepmc   +1 more source

Radio‐Activated Selenium‐Doped Janus Ag/Ag2SexSy Nanoparticles for Precise Cancer NIR‐II Fluorescence Imaging and Radiosensitization Therapy

Advanced Science, EarlyView.
A new kind of selenium‐doped Ag/Ag2S Janus nanoparticles (Ag/Ag2SexSy JNPs) is reported as radio‐responsive probes for specifically hydrogen peroxide (H2O2)‐activated cancer imaging and enhanced radiosensitization, offering a promising approach for precision cancer theranostics.
Kang Zhu, Zhanyuan Li, Jingjing Cao, Yixi Cao, Jimei Wang, Shiyu Wang, Ling Chen, Huiqin Zhou, Wei Huang, Hanxun Zou, Qunsheng Li, Jing Mu, Jibin Song   +12 more
wiley   +1 more source