Results 191 to 200 of about 36,702 (248)

Engineering antibodies with cancer‐associated binding sites

BMEMat, EarlyView.
This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian, Yumeng Pan, Yingchun Zhang, Fangling Wang, Zejun Wang   +4 more
wiley   +1 more source

Intensity-modulated proton therapy for hippocampal-sparing prophylactic cranial irradiation: a planning comparison with photon therapy. [PDF]

BMC Cancer
Yin X, Lin X, Zhang G, Yin Y, Sun T.
europepmc   +1 more source

X‐ray controlled release strategy in cancer therapy

BMEMat, EarlyView.
A comprehensive review on the design principles and current strategies of X‐ray stimulated release systems in cancer therapy, focusing on the X‐ray responsive functional groups and materials as well as discussing the advantages and current challenges of X‐ray controlled release systems in cancer therapy.
Yiling Ruan, Hongxiang Huang, Huihui Liu, Jinglang Gong, Changjun Li, Xiaolian Sun   +5 more
wiley   +1 more source

Cherenkov light emission in external beam radiation therapy of the larynx. [PDF]

J Biomed Opt
Dubal J, Arce P, South C, Florescu L.
europepmc   +1 more source

Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities

BMEMat, EarlyView.
This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan, Ye Zhu, Zhi Ye, Huayang Zhang, Junxi Wang, Guozhong Yi, Zhiyong Li, Rongyang Xu, Luyao Wang, Zhenzhen Wu, Songtao Qi, Guanglong Huang, Shanqiang Qu   +12 more
wiley   +1 more source

Monte Carlo simulation of a novel medical linac concept for highly conformal x-ray FLASH cancer radiotherapy. [PDF]

Sci Rep
Krim DE, Whelan B, Harkness M, Otto K, Loo BW, Bazalova-Carter M.   +5 more
europepmc   +1 more source

Improving total bone marrow and lymphoid irradiation: feasibility of intensity-modulated proton therapy (IMPT) and dosimetric comparison with helical tomotherapy (HT). [PDF]

Radiat Oncol
Sharma DS, Manikandan A, Singh G, Gayen S, Sundar S, G A, S R, Suhail M, S R, Krishnan G, Raj R, Chilukuri S, Easow J, Jalali R.   +13 more
europepmc   +1 more source

Immunosuppressive JAG2+ tumor‐associated neutrophils hamper PD‐1 blockade response in ovarian cancer by mediating the differentiation of effector regulatory T cells

Cancer Communications, EarlyView.
Abstract Background Tumor‐associated neutrophils (TANs) play a critical role in modulating immune responses and exhibit significant heterogeneity. Our previous study demonstrated that jagged canonical Notch ligand 2 (JAG2)+ TANs were associated with an immunosuppressive microenvironment in high‐grade serous ovarian cancer (HGSOC), but the underlying ...
Chenyang Wang, Moran Yang, Yujing Zhong, Kankan Cao, Xueling Wang, Chen Zhang, Yiying Wang, Mengdi He, Jiaqi Lu, Guodong Zhang, Yan Huang, Haiou Liu   +11 more
wiley   +1 more source

Planning and Dosimetry Study of Dynamic Intensity-Modulated Radiotherapy and Volumetric-Modulated Arc Therapy for Carcinomas of the Pharynx Using 6MV Flattening Filter and Flattening Filter-free Beams. [PDF]

J Med Phys
Rajadurai E, Saravana Kumar A, Govindarajan KN, Pandu B, Jacob S.   +4 more
europepmc   +1 more source

Novel molecular mechanisms of immune evasion in hepatocellular carcinoma: NSUN2‐mediated increase of SOAT2 RNA methylation

Cancer Communications, EarlyView.
Abstract Background Hepatocellular carcinoma (HCC) is a deadly malignancy known for its ability to evade immune surveillance. NOP2/Sun RNA methyltransferase family member 2 (NSUN2), an RNA methyltransferase involved in carcinogenesis, has been associated with immune evasion and energy metabolism reprogramming.
Jinhua Jiang, Feng Liu, Dan Cui, Caixia Xu, Jiachang Chi, Tinghua Yan, Fang Guo   +6 more
wiley   +1 more source