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Intensity modulated radiotherapy
2012Intensity-modulated radiotherapy (IMRT) is a radiation delivery technique that allows “dose sculpting” to improve target coverage while sparing normal tissues. In an IMRT plan, the number of photons delivered (or “fluence”) varies within a field. Such variability can be used to avoid normal structures with lower radiation tolerance than the cancer and ...
Bridget F. Koontz +2 more
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Exploration of tradeoffs in intensity-modulated radiotherapy
Physics in Medicine and Biology, 2005The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and we apply it to explore the tradeoff ...
David, Craft +2 more
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The Implementation of Intensity-modulated Radiotherapy in the UK
Clinical Oncology, 2010Radiotherapy in the UK lags behind that in much of Europe in terms of both the low proportion of cancer patients gaining access to treatment and the long waiting times [1] and [2]. The technical quality of radiotherapy is also a cause for concern.
M V, Williams +5 more
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Intensity-Modulated Radiotherapy for Pancreatic Adenocarcinoma
International Journal of Radiation Oncology*Biology*Physics, 2012To report the outcomes and toxicities in patients treated with intensity-modulated radiotherapy (IMRT) for pancreatic adenocarcinoma.Forty-seven patients with pancreatic adenocarcinoma were treated with IMRT between 2003 and 2008. Of these 47 patients, 29 were treated adjuvantly and 18 definitively.
Jonathan A, Abelson +11 more
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Intensity-modulated radiotherapy for sinonasal teratocarcinosarcoma
Journal of Huazhong University of Science and Technology [Medical Sciences], 2011Surgical excision and postoperative radiotherapy are widely accepted therapeutic modalities for sinonasal teratocarcinosarcoma (SNTCS). Previous studies have shown that intensity-modulated radiation therapy (IMRT) is safe and effective for the treatment of some sinonasal malignancies.
Gang, Peng +5 more
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Intensity-modulated radiotherapy of the female breast
Medical Dosimetry, 2002Current methods for intensity-modulated radiotherapy (IMRT) in breast cancer use forward planning based on equivalent radiological path length to design intensity modulated tangential beams. Compared to conventional tangential techniques, dose reduction of organs at risk is limited using these techniques.
Christoph, Thilmann +10 more
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Practical experience with intensity-modulated radiotherapy
The British Journal of Radiology, 2004At the Ipswich Hospital implementation of intensity-modulated radiotherapy (IMRT) commenced in February 2001 based on an established 3D conformal radiotherapy (3D CRT) service. This paper describes our experiences as we commissioned a fully-integrated IMRT planning and delivery system, and established IMRT within the department.
H V, James, C D, Scrase, A J, Poynter
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Conformal Radiotherapy and Intensity-modulated Radiotherapy: Clinical Data
Acta Oncologica, 2000Conformal radiotherapy (CRT) is based on three hypotheses: (i) a higher rate of local control can improve the survival rate; (ii) dose escalation can increase tumor control; and (iii) CRT allows the delivery of higher doses by decreasing the incidence of late effects. These postulates are now supported by several data.
M, Tubiana, F, Eschwège
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The Technique of Intensity-Modulated Radiotherapy in the Treatment of Cholangiocarcinoma
Tumori Journal, 2007Aims and background Conventional radiotherapy in inoperable cholangiocarcinoma is limited by radiotolerance of the surrounding tissues. The aim of our dosimetric study was an evaluation of intensity-modulated radiotherapy in the treatment of inoperable bile duct carcinoma.
Jiri Petera +5 more
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Intensity modulation methods for proton radiotherapy
Physics in Medicine and Biology, 1999The characteristic Bragg peak of protons or heavy ions provides a good localization of dose in three dimensions. Through their ability to deliver laterally and distally shaped homogenous fields, protons have been shown to be a precise and practical method for delivering highly conformal radiotherapy.
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