Results 211 to 220 of about 36,702 (248)

Targeted intracellular delivery of molecular cargo to hypoxic human breast cancer stem cells

open access: yes
Cancer Communications, EarlyView.
Ashley V. Makela   +7 more
wiley   +1 more source

Gradients and intensity modulated radiotherapy [PDF]

open access: possibleProceedings of the 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (Cat. No.00CH37143), 2002
A consequence of the advent of intensity modulated radiation therapy (IMRT) is the presence of large dose gradients surrounding the tumor, and the regions at risk (RAR's) near the tumor. Unlike standard radiotherapy, these gradients are not the chance result of a few beam choices, but rather they are strategically placed by the optimization software. A
Gustavo H. Olivera   +5 more
openaire   +1 more source

Intensity-Modulated Radiotherapy

The Cancer Journal, 2002
Intensity-modulated radiotherapy represents a recent advancement in conformal radiotherapy. It employs specialized computer-driven technology to generate dose distributions that conform to tumor targets with extremely high precision. Treatment planning is based on inverse planning algorithms and iterative computer-driven optimization to generate ...
C. Clifton Ling   +17 more
openaire   +3 more sources

Intensity modulation methods for proton radiotherapy [PDF]

open access: possiblePhysics in Medicine and Biology, 1999
The characteristic Bragg peak of protons or heavy ions provides a good localization of dose in three dimensions. Through their ability to deliver laterally and distally shaped homogenous fields, protons have been shown to be a precise and practical method for delivering highly conformal radiotherapy.
openaire   +2 more sources

Exploration of tradeoffs in intensity-modulated radiotherapy

Physics in Medicine and Biology, 2005
The purpose of this study is to calculate Pareto surfaces in multi-criteria radiation treatment planning and to analyse the dependency of the Pareto surfaces on the objective functions used for the volumes of interest. We develop a linear approach that allows us to calculate truly Pareto optimal treatment plans, and we apply it to explore the tradeoff ...
David Craft, Thomas Bortfeld, T Halabi
openaire   +3 more sources

The Implementation of Intensity-modulated Radiotherapy in the UK

Clinical Oncology, 2010
Radiotherapy in the UK lags behind that in much of Europe in terms of both the low proportion of cancer patients gaining access to treatment and the long waiting times [1] and [2]. The technical quality of radiotherapy is also a cause for concern.
Ranald I Mackay   +5 more
openaire   +3 more sources

Intensity-modulated radiotherapy of the female breast

Medical Dosimetry, 2002
Current methods for intensity-modulated radiotherapy (IMRT) in breast cancer use forward planning based on equivalent radiological path length to design intensity modulated tangential beams. Compared to conventional tangential techniques, dose reduction of organs at risk is limited using these techniques.
Christoph Thilmann   +10 more
openaire   +3 more sources

Practical experience with intensity-modulated radiotherapy

The British Journal of Radiology, 2004
At the Ipswich Hospital implementation of intensity-modulated radiotherapy (IMRT) commenced in February 2001 based on an established 3D conformal radiotherapy (3D CRT) service. This paper describes our experiences as we commissioned a fully-integrated IMRT planning and delivery system, and established IMRT within the department.
A. Poynter, C D Scrase, H.V. James
openaire   +3 more sources

Intensity-Modulated Radiotherapy for Pancreatic Adenocarcinoma

International Journal of Radiation Oncology*Biology*Physics, 2012
To report the outcomes and toxicities in patients treated with intensity-modulated radiotherapy (IMRT) for pancreatic adenocarcinoma.Forty-seven patients with pancreatic adenocarcinoma were treated with IMRT between 2003 and 2008. Of these 47 patients, 29 were treated adjuvantly and 18 definitively.
Ann Yuriko Minn   +11 more
openaire   +3 more sources

Intensity-Modulated Radiotherapy

2012
Intensity-modulated radiotherapy (IMRT) is a radiation delivery technique that allows “dose sculpting” to improve target coverage while sparing normal tissues. In an IMRT plan, the number of photons delivered (or “fluence”) varies within a field. Such variability can be used to avoid normal structures with lower radiation tolerance than the cancer and ...
Devon J. Godfrey   +2 more
openaire   +2 more sources

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