Results 161 to 170 of about 1,093,427 (365)

Mapping Use of Radiotherapy for Patients with Non-small Cell Lung Cancer in the Netherlands between 1997 and 2008

, 2012
Aim After the publication of several reports that the utilisation rate of radiotherapy for patients with non-small cell lung cancer (NSCLC) varies for both medical and non-medical reasons, the utilisation of radiotherapy was studied in four regions in ...
M.J. Aarts, Struikmans, H., J.W.W. Coebergh, C.C.E. Koning, Koning, C. C. E., Burgers, J. A., Janssen-Heijnen, M. L. G., H. Struikmans, Jobsen, J. J., Louwman, W. J., P.M.P. Poortmans, J.A. Burgers, J.J. Jobsen, Coebergh, J. W. W., Visser, O., Lybeert, M. L. M., M.L.G. Janssen-Heijnen, O. Visser, M.L.M. Lybeert, Aarts, M. J., Poortmans, P. M. P., W.J. Louwman   +21 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Early circulating EBV-DNA clearance predicts enhanced short-term treatment response and survival benefit in locally advanced nasopharyngeal carcinoma

BMC Cancer
Background and purpose This study investigates the correlation between the clearance of circulating Epstein-Barr virus DNA (cEBV-DNA) and treatment outcomes in locally advanced nasopharyngeal carcinoma (laNPC) patiePnts.
Xiameng Lu, Liru Zhu, Bibo Tan, Zhuowei Liang, Kaihua Chen, Suning Huang, Ling Li, Xiaodong Zhu   +7 more
doaj   +1 more source

Comparison between free breathing and deep inspiration breath hold in left-sided breast cancer treatment

Reports of Practical Oncology and Radiotherapy
BACKGROUND: This study aimed to compare the treatment plan between free breathing (FB) and deep inspiration breath-hold (DIBH) in patients with left-sided breast cancer. We aimed to investigate the dose to the heart and left lung.
Hideharu Miura, Yoshiko Doi, Soichiro Ishihara, Masahiko Kenjo, Minoru Nakao, Shuichi Ozawa, Masayuki Kagemoto   +6 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Radiotherapy [PDF]

Deutsches Ärzteblatt international, 2018
openaire   +2 more sources

CXCR2 affects sensitization of radioresistant HPV-negative head and neck squamous cell carcinoma cells by ABT-263

Radiation Oncology
Background Radiation-induced senescence strongly contributes to therapy resistance in HPV-negative head and neck squamous cell carcinoma (HNSCC). In particular, the NF- $${\rm{\kappa }}$$ B-dependent arm of the senescence-associated secretory phenotype ...
Sibylla Kohl, Mareike Schaper, José Arteaga Lajarín, Florentine S. B. Subtil, Rita Engenhart-Cabillic, Ekkehard Dikomey, Sebastian Adeberg, Ulrike Theiß   +7 more
doaj   +1 more source

Novel pharmacological perspectives in radiotherapy

, 2018
Radiotherapy is an integral part of oncotherapy, usually used in combination with surgical therapy and/or chemotherapy in order to enhance the overall effect.
Bánffy, Balázs
core  

Short-term preoperative radiotherapy results in down-staging of rectal cancer: a study of 1316 patients

, 1997
BACKGROUND AND PURPOSE: This study was undertaken to investigate down-staging effects after short-term, high-fractionated preoperative radiotherapy. MATERIAL AND METHODS: The relationships between preoperative radiotherapy 25-25.5 Gy given over 5-7 days ...
Dahlberg, M, Holmberg, L, Graf, W, Pählman, L, Glimelius, B,, Osman, MM   +5 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source