Results 51 to 60 of about 14,201 (265)

Inter-observer variability in radiotherapy contouring with the use of autocontouring software: A systematic review

Clinical and Translational Radiation Oncology
Inter-observer variability (IOV) in radiotherapy contouring remains a significant source of uncertainty, especially for complex anatomical regions.
Polly Darby, Emily Kilgour, Chee Kin Then, Andrew Bromiley, John McLellan, Anne E. Kiltie   +5 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Evolution of Radiotherapy: High-precision Radiotherapy [PDF]

, 2008
Technological advances that have been achieved over the last two decades in the area of treatment planning and sophisticated and complicated hardware capabilities, such as computer-controlled treatments, multileaf collimators, and incorporating imaging ...
김용배, 서창옥
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Computerised tomography in radiotherapy planning [PDF]

, 1983
Successful radiotherapy practice depends on the irradiation of tumours such that their destruction follows without unacceptable damage of the surrounding normal tissues. Until recently the accurate acquisition of data concerning the tumour anatomy lagged
Badcock, P.C. (Peter)
core   +1 more source

Radiation Planning Index for dose distribution evaluation in stereotactic radiotherapy

, 2008
AimThe aim of this study was to provide a parameter for treatment plan comparisons in clinical practice.Materials and Methods21 patients with brain tumours were selected for analysis. Two alternative treatment plans were calculated for each patient.
BYSTRZYCKA, Joanna; Department of Radiotherapy and Brachytherapy Planning, Maria Sklodowska Curie, Memorial Cancer Centre and Institute of Oncology, Gliwice Branch, Wybrzee Armii Krajowej 15, 44–101 Gliwice, Poland, GRZĄDZIEL, Aleksandra; Department of Radiotherapy and Brachytherapy Planning, Maria Sklodowska Curie, Memorial Cancer Centre and Institute of Oncology, Gliwice Branch, Wybrzee Armii Krajowej 15, 44–101 Gliwice, Poland, ŚLOSAREK, Krzysztof; Department of Radiotherapy and Brachytherapy Planning, Maria Sklodowska Curie, Memorial Cancer Centre and Institute of Oncology, Gliwice Branch, Wybrzee Armii Krajowej 15, 44–101 Gliwice, Poland, SZLAG, Marta; Department of Radiotherapy and Brachytherapy Planning, Maria Sklodowska Curie, Memorial Cancer Centre and Institute of Oncology, Gliwice Branch, Wybrzee Armii Krajowej 15, 44–101 Gliwice, Poland   +3 more
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Lung cancer. Radiotherapy in lung cancer: Actual methods and future trends

, 2014
This survey is performed to update knowledge about methods and trends in lung cancer radiotherapy. A significant development has been noticed in radiotherapeutic techniques, but also in the identification of clinical prognostic factors.
Maciejczyk, Adam; Radiotherapy Department, Lower Silesian Centre of Oncology, Wrocław, Poland, Skrzypczyńska, Iga; Radiotherapy Department, Lower Silesian Centre of Oncology, Wrocław, Poland, Janiszewska, Marzena; Medical Physics Department, Lower Silesian Centre of Oncology, Wrocław, Poland   +2 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Bridging the proton gap: A proton therapy consultation service for Canadian radiation oncologists

Technical Innovations & Patient Support in Radiation Oncology
Purpose: Canada is the only G7 country without a clinical proton beam therapy (PBT) facility. Patients can access publicly funded PBT through provincial out-of-country approval programs.
Inhwa Kim, Amy Parent, Michael Holwell, Tim Craig, Patricia Lindsay, Hillary Le, Yat Tsang, Perry B. Johnson, Danny J. Indelicato, Fei-Fei Liu, Derek S. Tsang   +10 more
doaj   +1 more source