Results 51 to 60 of about 6,097,379 (251)

Computer-assisted resection and reconstruction of pelvic tumor sarcoma [PDF]

open access: yes, 2010
Pelvic sarcoma is associated with a relatively poor prognosis, due to the difficulty in obtaining an adequate surgical margin given the complex pelvic anatomy.
Christian Delloye   +8 more
core   +1 more source

Critical assessment of synthetic accessibility scores in computer-assisted synthesis planning. [PDF]

open access: yes, 2022
Modern computer-assisted synthesis planning tools provide strong support for this problem. However, they are still limited by computational complexity.
Mateusz, Kitlas   +3 more
core   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Virtual 3D tumor marking-exact intraoperative coordinate mapping improve post-operative radiotherapy

open access: yesRadiation Oncology, 2011
The quality of the interdisciplinary interface in oncological treatment between surgery, pathology and radiotherapy is mainly dependent on reliable anatomical three-dimensional (3D) allocation of specimen and their context sensitive interpretation which ...
Essig Harald   +9 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Multicentre prospective risk analysis of a fully automated radiotherapy workflow

open access: yesPhysics and Imaging in Radiation Oncology
Background and Purpose: Fully automated workflows (FAWs) for radiotherapy treatment preparation are feasible, but remain underutilized in clinical settings.
Geert De Kerf   +14 more
doaj   +1 more source

Computer Assisted Survey Information Collection

open access: yes
The Subcommittee on Computer Assisted Survey Information Collection investigated the use of computers in collecting survey information. This report covers the different ways in which small computers can be used to improve data collection.
United States. Federal Committee on Statistical Methodology. Subcommittee on Computer Assisted Survey Information Collection
core   +1 more source

09471 Executive Summary – Computer-assisted proofs - tools, methods and applications [PDF]

open access: yes, 2010
From November 15-20, 2009, the Dagstuhl seminar on "Computer-assisted proofs - tools, methods and applications" continued a series of previous successful seminars. Participants from 10 different countries presented recent results in verification methods,
Rump, Siegfried M.   +3 more
core   +1 more source

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

open access: yesFEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao   +23 more
wiley   +1 more source

Spatially Configurable Conformal Sensor Integration on an Ultra‐Fine Metallic Needle for Minimally Invasive Deep‐Tissue Oxygen Monitoring

open access: yesAdvanced Materials Technologies, EarlyView.
A multi‐point oxygen‐sensing ultra‐fine needle (MO‐UFN) is developed by conformally integrating a lithographically patterned flexible electrochemical sensor array onto a clinical acupuncture needle. The platform preserves an approximately 0.3 mm diameter while enabling spatially resolved oxygen profiling along the insertion pathway.
Yeju Seo   +9 more
wiley   +1 more source

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