Results 111 to 120 of about 106,552 (312)

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Assessment the impact of hybrid dose rates intensity modulated radiation therapy planning technique in patients with head and neck cancer

Egyptian Journal of Cancer and Biomedical Research
Background: Head and neck cancer incidence is high with radiotherapy representing integral part of treatment with different advanced techniques emerging along with different adverse events profile for each evolving technique.
ahmed adel, Omneya elemary, Hanady hegazy, Mohamed Abougylah, wahib attia   +4 more
doaj   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

Radiation-induced hypoglossal nerve palsy after definitive radiotherapy for nasopharyngeal carcinoma: Clinical predictors and dose–toxicity relationship

, 2019
Background and purpose: Radiation-induced hypoglossal nerve palsy is a debilitating and irreversible late complication after definitive radiotherapy for nasopharyngeal carcinoma (NPC) and other skull base tumors.
Ngan, KCR, Lee, FKH, Lee, J, Wong, KH, Chow, JCH, Cheung, KM, Leung, AKC, Lee, AWM, Li, KWS, Au, KH, Yiu, HHY, Chan, JCH, Zee, BCY   +12 more
core   +1 more source

An Evaluation of Atlas Selection Methods for Atlas-Based Automatic Segmentation in Radiotherapy Treatment Planning [PDF]

, 2019
Atlas-based automatic segmentation is used in radiotherapy planning to accelerate the delineation of organs at risk (OARs). Atlas selection has been proposed as a way to improve the accuracy and execution time of segmentation, assuming that, the more
van Soest, Johan; id_orcid, Lustberg, T., van Soest, J., Peressutti, D., Peressutti, D, Schipaanboord, Bas, Peressutti, Devis, Lustberg, Tim, Boukerroui, D., van Soest, Johan, van Elmpt, W, Dekker, Andre, Lustberg, T, Boukerroui, D, Schipaanboord, B., Dekker, A.T. (Alexander) den, van Soest, J, Gooding, M.J., van Elmpt, Wouter, Gooding, Mark J., Dekker, AT, Gooding, MJ, Boukerroui, Djamal   +22 more
core   +1 more source

Small Extracellular Vesicles‐Derived Circ6718 Unlocks Stromal Remodeling and Serves as a Biomarker in Gastric Cancer

Advanced Science, EarlyView.
sEVs‐circ6718 serves as a promising serum biomarker for gastric cancer early diagnosis and prognosis, promoting malignant transformation in gastric cancer cells and GC‑MSC differentiation into CAFs. sEVs‑circ6718 holds potential as a biomarker for the early diagnosis and prognostic assessment of gastric cancer.
Fan Zhang, Xueyan Zang, Dongli Wang, Rong Li, Hui Qian, Wenrong Xu, Jiajia Jiang, Yongmin Yan   +7 more
wiley   +1 more source

Repeat CT imaging and adaptive planning during radiotherapy for locally advanced lung cancer

, 2014
Purpose/Objective: Many patients with lung cancer have tumor changes like shrinkage, improvement in atelectasis or mediastinal replacement during radiotherapy.
Omurca, A., Aydemir, Selcen, Yıldırım Altınok, Ayşe, Çağlar, Hale, Sertkaya, Helin, Küçükmorkoç, Esra, Acar, Hilal   +6 more
core  

Dual‐Physical‐Field Nanocatalysis: Injectable Hydrogel Enables Piezo‐Photothermal Synergy for Breast Cancer Therapy

Advanced Science, EarlyView.
ABSTRACT Piezocatalytic therapy (PCT) harnesses mechanical energy to generate tumor‐lethal reactive oxygen species (ROS), but its efficacy is limited by rapid electron‐hole recombination and poor intratumoral retention. To overcome these limitations, we engineered heterostructured BiOCl@CuO nanosheets embedded in an injectable, conductive ...
Can Tian, Shihan Xiao, Xuan Chen, Danni Zhang, Zizhen Liu, Jing Wang, Ning Xie, Wei Li   +7 more
wiley   +1 more source

ADAPTATION OF LINEAR-QUADRATIC MODEL FOR PLANNING NEUTRON THERAPY REGIMENS

Сибирский онкологический журнал, 2016
Based on the fact that the parameters of the linear-quadratic model for neutron therapy were found, the comparison of single therapeutic doses in neutron therapy, calculated using the TDF (time-dose-fractionation) and linear-quadratic (LQ) models were ...
V. A. Lisin, V. V. Velikaya, I. A. Miloichikova   +2 more
doaj  

Benefits and difficulties during brain radiotherapy planning with hippocampus sparing

, 2019
Radiotherapy (RT) is frequently used in the treatment of primary and secondary brain tumours, as well as in prophylactic cranial irradiation (PCI). The hippocampus plays a key function in the process of remembering, relaying information from short-term ...
Wojtukiewicz, Marek Z.; Oncology Clinic, Medical University of Bialystok, Poland, Poland, Konopka-Filippow, Monika; Oncology Clinic, Medical University of Bialystok, Poland, Poland, Sierko, Ewa; Oncology Clinic, Medical University of Bialystok, Poland, Poland; Department of Radiotherapy, Białystok Centre of Oncology, Poland   +2 more
core   +1 more source